安体舒通对慢性心力衰竭的疗效价值     

孙恕  左剑锋  幸志强  邱丽红  易祥武  陈芳明 《宜春学院学报》2011,33(4)

目的:探讨小剂量安体舒通治疗慢性心力衰竭的疗效.方法:入选慢性心力衰竭患者76例,随机分为安体舒通(A组)和对照组(B组),均予标准三联抗心衰治疗,A组联用安体舒通(20-40mg/d)B组不加安体舒通.治疗前和治疗后6周分别进行心功能(NYHA)分级评估,超声心动图、6分钟步行距离为客观指标,借以评价心功能改善程度.结果:治疗6周后A、B两组心功能分级、左室收缩末期内径(mm)、6分钟步行距离均显著改善(P＜0.05);与B组比较,A组改善更显著(P＜0.05)结论:应用小剂量安体舒通治疗CHF疗效肯定.  相似文献   

走开,我想一个人静静     

大J 《家教世界》2019,(1)

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祸起『不走心的夸奖』 孩子输不起?     

大J 《家教世界》2019,(11)

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Complacent and conflicting scientific expertise in British and American drug regulation: clinical risk assessment of triazolam     

Abraham J  Sheppard J 《Social studies of science》1999,29(6):803-843

This paper presents a case study in the production and interpretation of regulatory science, focusing on the conflicting British and American clinical risk assessments of triazolam (Halcion) - the most controversial sleeping pill in the world. The regulation of triazolam is shown to be more permissive in the USA than in the UK. Six principal socio-political factors are put forward to explain this; differential regulatory trust; regulators' socio-technical data selections; medico-scientific disciplinary influences; organizational and professional interests; conflicts of interest of expert advisers; and the growth of the neo-liberal regulatory state. The risk assessments of both the British and American regulatory agencies are shown to be complacent relative to technical standards which the agencies themselves later accepted. It is suggested that, when the interests of pharmaceutical manufacturers and patients diverge, regulatory assessments are crucially affected by whether regulators are predisposed to award the benefit of the scientific doubts to the manufacturers or patients, and by the balance of such predispositions both within and between regulatory institutions of scientific expertise. The triazolam case indicates that the amount of trust placed in the pharmaceutical industry by the British American regulatory systems may hamper detection of flaws in manufacturers' medical data in a timely manner and, as a consequence, compromise patients' interests. Some policy implications for drug regulation are sketched.  相似文献   

The effect of submaximal exercise on recovery hemodynamics and thermoregulation in men and women     

Fisher M  Paolone V  Rosene J  Drury D  Van Dyke A  Moroney D 《Research quarterly for exercise and sport》1999,70(4):361-368

Five women and 5 men were studied to examine the effects of submaximal exercise on thermoregulatory and hemodynamic variables during recovery in two environments: (a) control (C), 22 degrees C, 33% rh; and (b) hot humid (H), 32 degrees C. The participants exercised on a cycle ergometer at 60% of peak oxygen consumption for 35 min prior to 90 min of seated recovery. Sessions were identical, except for environment. Variables evaluated (p < .05) were: core temperature (TR), mean skin temperature (Ts), sweat rate (SR), heart rate (HR), stroke index (SI), cardiac index (CI), forearm blood flow (FBF), systolic blood pressure (SBP), and diastolic blood pressure (DBP). Men and women exhibited similar patterns of TR, Ts, and SR in both environments. Ts and SR (collapsed means for gender) were higher in the H than in the C. DBP was higher in men than in women throughout recovery in both environments. With combined means for gender, HR was higher in the H than in the C. CI, SI, FBF, and SBP were similar in both environments and returned to baseline within 15 min into recovery. These data suggest that heat dissipation during extended recovery was accomplished with similar contributions of cutaneous vasodilation and sweating in M and F. Furthermore, the moderate exercise level did not influence hemodynamics beyond 15 min of recovery in either environment.  相似文献   

刍议大众体育健身市场     

曹中江  左新荣 《四川体育科学》1999,(1):6-8

我国大众体育健身,在市场商业化的运作过程中对象的显贵性,消费的超前性、奢侈性,使大众体育健身市场所指对的全民健康和精神文明的建设,形成了某种非美状态的不平衡、不和谐。本文在表述我国社会主义初级阶段现状与特征的基础上,提出了我国大众体育健身场所作为卖方市场,应时刻注视大众工薪群体可以接受的健身消费程度以及立足现实,把体育健身市场的社会目标定在为建设我国现代化强国而造就人、美化人的境界上。  相似文献   

Global Policy and National Research: The International Shaping of Climate Research in Four European Union Countries     

Nolin J 《Minerva》1999,37(2):125-140

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GaIN (Georgia Interactive Network for Medical Information) study on health professionals' search requests and continuing education needs     

LaBeause J  Van de Water N  Carey P  Fielder M  Sorrow B  Woolbright C 《Medical reference services quarterly》1999,18(2):81-89

Health sciences librarians are being called upon to be more proactive in their institutions' continuing education efforts. In an effort to identify whether search requests indicated CE needs, a study was conducted by a group of members of GaIN (Georgia Interactive Network for Medical Information). MEDLINE requests from health care professionals for subject specific clinical topics were collected during a six-month period via a standard search request form created for the study. Copies of all completed requests were collected and broad ICD-9 codes assigned to the search topics. Institutional reports were generated for each participating library to share with hospital CE coordinators. They were also compiled for the group as a whole, and reflected the "hottest" topics requested during the study period for physicians and for non-physicians (nurses, allied health, administrators). A survey to hospital librarians and CE educators showed some value in the reports, but greater potential for further collaboration between librarians and CE coordinators.  相似文献   

Tracing the evolution of critical evaluation skills in students' use of the Internet     

Blumberg P  Sparks J 《Bulletin of the Medical Library Association》1999,87(2):200-205

This paper documents the evolving uses of the Internet made by public health graduate students and traces the development of their search methods and critical evaluative criteria. Early in the first semester and again six months later, twenty-four graduate students in a problem-based learning curriculum, which emphasizes evidence-based critical thinking skills, were required to describe their most helpful resources and to evaluate these resources critically. The answers were coded for the types of resources the students used, how frequently they were used, and why they were used. Student perception of the usefulness of resources, especially the Internet, and ability to evaluate these resources critically changed greatly. Initially, 96% of the students stated that the Internet was their most helpful resource. Six months later, these students continued to use the Internet; however, it was not their most useful source. At the later point, students had very specific uses for the Internet. Their most frequently used evaluation criterion was the reliability and objectivity of the source of the information. By the end of the first year of study, the majority of the students demonstrated an understanding of the principles of evidence-based practice and applied them to their research and analysis of information resources.  相似文献   

Characteristics of peer reviewed clinical medicine journals     

Eldredge J 《Medical reference services quarterly》1999,18(2):13-26

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