An Interesting Case of Polyuria in a Child     

Arabinda Mohan Bhattarai  Arun Sharma  Sulochana Parajuli  Suju Mool 《Indian journal of clinical biochemistry : IJCB》2018,33(3):365-367

A 1 year old male child with increased frequency of urine associated with increased thirst was found to have some developmental delays. Laboratory investigations showed increased serum sodium level and serum osmolality with decreased urine osmolality. An empty sella turcica was seen in contrast brain MRI; however focal demyelinating lesion was not present. He was managed with intranasal desmopressin therapy. Developmental delays in such cases can be prevented by early referral to a tertiary health care center where laboratory and imaging facilities are available.  相似文献   

Synergetic Interaction of HLA-DRB1*07 Allele and TNF-Alpha − 863 C/A Single Nucleotide Polymorphism in the Susceptibility to Systemic Lupus Erythematosus     

Shiva Krishna Katkam  Liza Rajasekhar  Fathima S. D. Tasneem  Vijay Kumar Kutala 《Indian journal of clinical biochemistry : IJCB》2021,36(1):59

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease which is characterized by dysregulation of various cytokines propagating the inflammatory processes that is responsible for tissue damage. Tumor necrosis factor alpha (TNF-α) is one of the most important immunoregulatory cytokines that has been implicated in the different autoimmune diseases including SLE. Two hundred and two patients with SLE and 318 controls were included in the study. The TNF-α gene promoter region (from − 250 to − 1000 base pairs) was analyzed by direct Sanger’s DNA sequencing method to find promoter variants associated with South Indian SLE patients. We have analyzed six TNF-α genetic polymorphisms including, − 863C/A (rs1800630), − 857C/T (rs1799724), − 806C/T (rs4248158), − 646G/A (rs4248160), − 572A/C (rs4248161) and − 308G/A (rs1800629) in both SLE patients and controls. We did not find association of TNF-α gene promoter SNPs with SLE patients. However, the − 863A (rs1800630) allele showed association with lupus nephritis phenotype in patients with SLE (OR: 1.62, 95%CI 1.04–2.53, P = 0.034). We found serum TNF-α level was significantly elevated in SLE cases as compared to control and found no association with any of the polymorphisms. The haplotype analysis revealed a significant protective association between the wild TNF-α alleles at positions − 863C, − 857C, − 806C, − 646G, − 572A and − 308G (CCCGAG) haplotype with lupus nephritis phenotype (OR 0.53, 95% CI 0.35–0.82, P = 0.004). Additionally, the TNF-α − 863 C/A (rs1800630) polymorphism and HLA-DRB1*07 haplotype showed significant differences between SLE patients and controls (OR 4.79, 95% CI 1.73–13.29, P = 0.0009). In conclusion, TNF-α − 863A allele (rs1800630) polymorphism is associated with increased risk of nephritis in South Indian SLE patients. We also found an interaction between HLA-DRB1*07 allele with TNF-α − 863 C/A promoter polymorphism giving supportive evidence for the tight linkage disequilibrium between TNF-α promoter SNPs and MHC class II DRB1 alleles.  相似文献   

‘Communication sovereignty’ as resistance: strategies adopted by women farmers amid the agrarian crisis in India     

Mohan Jyoti Dutta  Jagadish Thaker 《Journal of Applied Communication Research》2019,47(1):24-46

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National initiative on undergraduate science
Calling scientists to visit HBCSE     

B. N. Dwivedi  A. Mohan 《Resonance》2005,10(1):16

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Acknowledgements     

Mohan Delampady 《Resonance》1999,4(6):i-i

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MEDIA STUDIES AND VOCATIONALISM     

Terence Mohan 《Learning, Media and Technology》1976,2(2):57-59

University arts faculties have traditionally been reluctant to admit a vocational component into arts courses. The author's experience in teaching media at the New South Wales Institute of Technology suggests that the fears underlying this reluctance, while not completely irrational, arise from problems between academics and professionals who cannot work well together: they can be overcome if those involved behave with tact and flexibility. The approach to media studies in Australia is described.  相似文献   

Cross-Sectoral Differences in Intellectual Property Enforcement in Developing Countries: The Role of State-Industry Linkages     

Krishna P. Jayakar 《The Information Society》2013,29(2):155-169

Leading developing countries have recently introduced some reforms in their national intellectual property regimes to harmonize them with international treaties and agreements. However, major differences remain in how these laws are applied to different information industries, and how they are enforced on the ground. While intellectual property law applies to a host of information products ranging from music to computer programs, governments have selectively enforced the law in some information industries, while neglecting to extend the same protection to others. Based on the comparative institutionalist approach, this article identifies two variables--state-industry linkages and level of innovative activity--that may explain the selective enforcement of intellectual property law. Intellectual property rights were expected to be better protected in information industries with strong state-industry linkages and higher levels of domestic innovation. This expectation was tested through a comparative study of four intellectual property industries from the Asian region. The results confirmed the expectation, but also demonstrated that strong state-industry linkages may independently correlate with high levels of intellectual property protection, even in industries where the current levels of innovative activity are low.  相似文献   

Interrelationship Between Procalcitonin and Organ Failure in Sepsis     

Dimple Anand  Sabari Das  Sumit Ray  Seema Bhargava  Lalit Mohan Srivastava 《Indian journal of clinical biochemistry : IJCB》2014,29(1):93-96

Sepsis suffers from lack of specific clinical symptoms which contribute to one of the major causes of mortality. In the present study, our aim was to evaluate the role of a recent biomarker Procalcitonin (PCT) in predicting organ dysfunction. 71 patients admitted with sepsis were included in the study. PCT levels were measured at 0, 24, 72 h and 7th day and sequential organ failure assessment score (SOFA) scores were calculated. PCT levels significantly decreased (p < 0.001) in 89.3 % of surviving patients, whereas, in 60 % non surviving patients the PCT level increased significantly (p < 0.001). A significant positive correlation between PCT and SOFA score was observed in survivors at each hour. These observations indicate that PCT concentration is significantly associated with severity of multi organ dysfunction and also helps in determining the prognosis of septic patients.  相似文献   

Self presentation in online environments: a study of Indian Muslim matrimonial profiles     

Smeeta Mishra  Mathukutty M. Monippally  Krishna P. Jayakar 《亚洲交流杂志》2013,23(1):38-53

This study examines the self presentation practices of Indian Muslim men and women in online matrimonial advertisements. Findings indicate that while Indian Muslims are using the new medium to adhere to traditional cultural and religious values, they are also making critical adjustments to adapt to the medium itself. While Muslim men and women claimed to possess different attributes in their profiles drawing upon gender role expectations in Indian society, they were identical in their preference for light skin or what is termed as ‘fair complexion’ in Indian English. An overwhelming majority of advertisers claimed to possess desirable skin tones and body types. Few Indian Muslim profiles highlighted external manifestations of religiosity, such as praying five times a day, wearing a hijab or burqa, and observing Ramadan. Further, results of this study also illuminate the influence of South Asian culture on Islamic practice, which is evident in the mention of caste identifications in the online matrimonial profiles.  相似文献   

Affirmative action in higher education in India: targeting,catch up,and mismatch     

Veronica Frisancho  Kala Krishna 《Higher Education》2016,71(5):611-649

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