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Zhao YE Peng Y Wang XL Wu LP Wang M Yan HL Xiao SX 《Journal of Zhejiang University. Science. B》2011,12(12):1008-1015
Demodex has been considered to be related with multiple skin disorders, but controversy persists. In this case-control study, a survey
was conducted with 860 dermatosis patients aged 12 to 84 years in Xi’an, China to identify the association between facial
dermatosis and Demodex. Amongst the patients, 539 suffered from facial dermatosis and 321 suffered from non-facial dermatosis. Demodex mites were sampled and examined using the skin pressurization method. Multivariate regression analysis was applied to analyze
the association between facial dermatosis and Demodex infestation, and to identify the risk factors of Demodex infestation. The results showed that total detection rate of Demodex was 43.0%. Patients aged above 30 years had higher odds of Demodex infestation than those under 30 years. Compared to patients with neutral skin, patients with mixed, oily, or dry skin were
more likely to be infested with Demodex (odds ratios (ORs) were 2.5, 2.4, and 1.6, respectively). Moreover, Demodex infestation was found to be statistically associated with rosacea (OR=8.1), steroid-induced dermatitis (OR=2.7), seborrheic
dermatitis (OR=2.2), and primary irritation dermatitis (OR=2.1). In particular, ORs calculated from the severe infestation
(≥5 mites/cm2) rate were significantly higher than those of the total rate. Therefore, we concluded that Demodex is associated with rosacea, steroid-induced dermatitis, seborrheic dermatitis, and primary irritation dermatitis. The rate
of severe infestation is found to be more correlated with various dermatosis than the total infestation rate. The risk factors
of Demodex infestation, age, and skin types were identified. Our study also suggested that good hygiene practice might reduce the chances
of demodicosis and Demodex infestation. 相似文献
42.
Liao F Zhu XY Wang YM Zhao YS Zhu LP Zuo YP 《Journal of Zhejiang University. Science. B》2007,8(4):237-241
The correlation of serum arylesterase (PON1) activity on phenylacetate determined by an integrated method to classical biochemical indexes of liver damage was investigated for the use of PON1 activity to evaluate liver damage. PON1 reaction curve as absorbance at 270 nm for 0.20 mmol/L phenylacetate hydrolysis was analyzed by the integrated method to determine maximal PON1 reaction rate. Classical biochemical indexes of liver damage were determined routinely. The 95% confidence threshold of PON1 activity in sera from healthy individuals was 2.12 mkat/L [(4.73±1.31) mkat/L, n=105]. PON1 activity in clinical sera was closely correlated to serum albumin, total protein and the ratio of albumin to globulins, but was weakly correlated to both direct and total bilirubin in serum. There were no correlations of PON1 activity to γ-glutamyltransferase, alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase. Among 127 clinical sera with PON1 activity＞2.12 mkat/L, there were 92% healthy individuals examined by albumin, 90% healthy individuals examined by total protein, 88% healthy individuals examined by total bilirubin, 86% healthy individuals examined by direct bilirubin and 64% healthy individuals examined by the ratio of albumin to globulins, respectively. In each group of healthy individuals judged by classical biochemical indexes of close correlation to PON1 activity, percentage of healthy individuals examined by PON1 activity was always ＞80%. These results suggested PON1 activity on phenylacetate estimated by the integrated method was also suitable for the evaluation of liver damage. 相似文献
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初中阶段的学生已经具备一定的自主管理意识和能力,班主任在落实班级管理过程中可以将学生的自主管理作为基础,鼓励并且引导学生参与到班级管理中,创新管理措施,激发学生的自我管理能动意识,同时通过观察学生及班级整体氛围的变化来调整管理思路和方法,在实践中验证管理措施的可行性,进而在完成班级管理任务和实现管理目标的基础上,全面培养学生的团队精神、综合素质、责任意识,并且通过良好的自主管理氛围提升学生对班级的认同感以及归属感。 相似文献