Engaging Actively with Issues in the Responsible Conduct of Science: Lessons from International Efforts Are Relevant for Undergraduate Education in the United States     

John D. Clements  Nancy D. Connell  Clarissa Dirks  Mohamed El-Faham  Alastair Hay  Elizabeth Heitman  James H. Stith  Enriqueta C. Bond  Rita R. Colwell  Lida Anestidou  Jo L. Husbands  Jay B. Labov 《CBE life sciences education》2013,12(4):596-603

Numerous studies are demonstrating that engaging undergraduate students in original research can improve their achievement in the science, technology, engineering, and mathematics (STEM) fields and increase the likelihood that some of them will decide to pursue careers in these disciplines. Associated with this increased prominence of research in the undergraduate curriculum are greater expectations from funders, colleges, and universities that faculty mentors will help those students, along with their graduate students and postdoctoral fellows, develop an understanding and sense of personal and collective obligation for responsible conduct of science (RCS). This Feature describes an ongoing National Research Council (NRC) project and a recent report about educating faculty members in culturally diverse settings (Middle East/North Africa and Asia) to employ active-learning strategies to engage their students and colleagues deeply in issues related to RCS. The NRC report describes the first phase of this project, which took place in Aqaba and Amman, Jordan, in September 2012 and April 2013, respectively. Here we highlight the findings from that report and our subsequent experience with a similar interactive institute in Kuala Lumpur, Malaysia. Our work provides insights and perspectives for faculty members in the United States as they engage undergraduate and graduate students, as well as postdoctoral fellows, to help them better understand the intricacies of and connections among various components of RCS. Further, our experiences can provide insights for those who may wish to establish “train-the-trainer” programs at their home institutions.  相似文献   

Optimizing Instructional Video for Preservice Teachers in an Online Technology Integration Course     

Mohamed Ibrahim  Rebecca Callaway  David Bell 《The American journal of distance education》2013,27(3):160-169

This study assessed the effect of design instructional video based on the Cognitive Theory of Multimedia Learning by applying segmentation and signaling on the learning outcome of students in an online technology integration course. The study assessed the correlation between students’ personal preferences (preferred learning styles and area of specialization) and their learning outcomes. A three-group pretest–posttest design was employed to assess whether there were significant differences in students’ test scores after they watched an instructional video. The results of the analysis of covariance (ANCOVA) analysis indicate that instructional design had a significant effect on students’ learning outcome. This effect was demonstrated by the statistically significant differences in students’ learning outcomes, with the highest scores achieved by students in the segmented and signaled video group and the lowest scores in the no-segmentation and no-signaling group. Moreover, results indicate that students’ learning preferences and area of specialization related significantly and positively to their learning outcomes. These findings suggest that the use of educational video in online courses has the potential to effectively improve students’ learning outcome; however, it requires design manipulation. The results also emphasize the importance of rethinking the one-size-fits-all approach in developing online course content and include consideration of the students’ learning preferences and area of specialization to optimize their learning.  相似文献   

Study on Urinary Candidate Metabolome for the Early Detection of Breast Cancer     

Faten Zahran  Ramzy Rashed  Mohamed Omran  Hossam Darwish  Arafa Belal 《Indian journal of clinical biochemistry : IJCB》2021,36(3):319

A metabolomic study for determination of certain urinary metabolomes, 1-methyladenosine (1-MA), 1-methylguanosine (1-MG), and 8-hydroxy-2′ deoxyguanosine (8-OHdG) in urine specimens of breast cancer patients. The accuracy of these metabolites and their combined score with cancer antigen 15-3 (CA15-3) was developed to improve the early detection of breast cancer. This study recruited 52 healthy individuals, 47 benign breast tumors, and 167 malignant breast tumor patients. Urine samples were handled to adjust the creatinine concentrations to 8 mg/dL (0.7 mmol/L) and analyzed using GC–MS to detect and quantify the selected urinary metabolomes in urine samples of all participants. The accuracy of individual urinary metabolomes and their combination with CA15-3 were evaluated using multivariate statistical analysis. The cutoff value of CA15-3 was 32.5 U/mL. Cutoff values of 1-MA, 1-MG, and 8-OHdG were 2.19, 2.1, and 7.3 µmol/mmol creatinine, respectively. The concentrations of 1-MA, 1-MG, and 8-OHdG were significantly higher in breast cancer patients, especially in the early-stage. The combination of three urinary metabolomes with CA15-3 improves the diagnostic sensitivity of breast cancer. For the combined score, the area under the curve (AUC) value of combined score ranged from 0.820 to 0.950, with high accuracy, ranged from 77.0 to 95.5%. The most significant AUC (0.973), sensitivity (90.1%), selectivity (94.0%) was recorded at comparing the healthy control with the early-stage of malignant breast cancer. In conclusion, the combination of three urinary metabolomes with serum CA15-3 improves the diagnostic sensitivity of breast cancer.  相似文献   

Evaluation of Apoptotic Marker Bcl2, CD4+, Human Hepatocyte Growth Factor and Metalloproteinase-9 as Tumor Markers for Patients with Hepatocellular Carcinoma     

Eman R. Youness  Mohamed El Nemr  F. S. Oraby  Nadia M. Ahmed  Mohamed A. Moghni  Hanan F. Aly  Hanaa H. Ahmed 《Indian journal of clinical biochemistry : IJCB》2014,29(3):351-356

To examine the possible involvement of human B cell leukemia/lymphoma 2 (Bcl-2), CD4+ cells, hepatocyte growth factor (HGF), and metalloproteinase-9 (MMP-9), as biomarkers in early diagnosis of hepatocellular carcinoma (HCC), activities of these biomarkers in serum were demonstrated by the method of Enzyme Linked Immunosorbant Assay. Two groups of subjects (60 for each), were examined in this study; healthy controls and patients with HCC. The present results declare that, significant decrease in Bcl-2 (p ≤ 0.0001), and CD 4+ (p ≤ 0.001), while significant increase in HGF and MMP-9 (p ≤ 0.05). These findings imply an influence of these biomarkers by the existence of hepatic carcinoma that might reflect the progression of disease and a distinction between the pathological mechanisms involved in hepatic carcinoma. Since, the serum MMP-9 activity was significantly varied between each stage of HCC. An individual profile of the present investigated parameters was detected that might serve as an easy accessing serum marker to monitor the progression of hepatic cell disorders.  相似文献   

Modalités de prise de décision chez les filles et les garçons en la présence ou en l’absence de l’enseignant     

Makram Zghibi  Hajer Sahli  Mohamed Jabri  Samira Ouelhezi  Noomen Guelmemi  Nathalie Wallian 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》2013,59(6):751-769

How girls and boys take decisions in the presence and absence of a teacher – This work is part of an innovative approach to physical and sports education in Tunisia, and team sports in particular. It uses language studies carried out within the framework of this teaching both to generate a reflective attitude on the part of students, and to identify the effect of gender as a variable in the ways in which they make decisions. Discourse analysis highlights the importance of language output by girls and boys in football teaching when a teacher is present or absent. The teacher is an institutional authority who imposes specific uses of language, and when he/she is absent, emotional tensions predominate and may reflect the repression of ideas that occurs when the teacher is present. Although girls appear to take part in the discussion, their utterances are fewer in number, and their analytical statements less effective than those of boys. Girls never gain the upper hand over boys. The study also suggests a redefinition of social role divisions on the basis of gender – masculinity and femininity.  相似文献   

Modeling, simulation, and applied optimization     

Mohamed El-Tarhuni  Jamal A. Abdalla  Ibrahim Sadek  Ismail Kucuk  Mahmoud Anabtawi  Mohammad Al-Jarrah 《Journal of The Franklin Institute》2011,348(7):1161-1162

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Designing e-assessment activities appropriate to learner's competency levels: Hybrid pedagogical framework and authoring tool     

El Asame  Maryam  Wakrim  Mohamed  battou  Amal 《Education and Information Technologies》2022,27(2):2543-2567

Education and Information Technologies - E-Assessment, which is a key element in the instructional design process, plays a major role in supporting and enhancing learning. However, the current...  相似文献   

Trends in the use of affective computing in e-learning environments     

Mejbri  Nesreen  Essalmi  Fathi  Jemni  Mohamed  Alyoubi  Bader A. 《Education and Information Technologies》2022,27(3):3867-3889

Education and Information Technologies - Considering that emotions have a great impact on motivation, reasoning, and decision making, affective computing methods, that were designed to attempt to...  相似文献   

Relationship between split-step timing and leg stiffness in world-class tennis players when returning fast serves     

Sami Mecheri  Guillaume Laffaye  Céline Triolet  David Leroy  Matt Dicks  Mohamed A. Choukou 《Journal of sports sciences》2013,31(17):1962-1971

ABSTRACT

This study investigated split-step timing when returning serves and whether this timing is related to neuromechanical capabilities in world-class tennis players. In Experiment 1, the split-step timing of four groups of world-class players (male and female ATP/WTA seniors, and ITF juniors) was measured on court when returning serves of the same level players. The four groups initiated the split-step at a similar time, starting around the time ball-racket contact in the serve stroke and landed when early ball-flight information was available. In Experiment 2, the neuromechanical capabilities (leg stiffness and vertical jump performance) of a group of world-class players and three groups of less-skilled tennis players were examined. The results showed an increase in leg stiffness with an increase in the level of expertise. A cross-experiment analysis in world-class male players (ATP/ITF, n = 10) revealed that the timing of initial foot movement was significantly correlated with the leg stiffness (r² = 0.54), with later lateral step after the serve in the players who had higher stiffness. The findings support the hypothesis that world-class tennis players adapt perceptual-motor control on the basis of their neuromechanical capabilities and maximise the time before initiating their interceptive action to rely on more reliable information.  相似文献   

Effects of plyometric jump training on the physical fitness of young male soccer players: Modulation of response by inter-set recovery interval and maturation status     

Rodrigo Ramirez-Campillo  Cristian Alvarez  Javier Sanchez-Sanchez  Maamer Slimani  Paulo Gentil  Mohamed Souhaiel Chelly 《Journal of sports sciences》2013,31(23):2645-2652

ABSTRACT

The effects of plyometric jump training on the physical fitness of male youth (age = 10–17 years) soccer players was examined in relation to inter-set recovery intervals and the maturity of the players in a single-blind, randomized-and controlled crossover trial. Jumping tests and kicking velocities were measured before (T₀), after a 6 week control period (T₁), after 6 weeks of plyometrics (T₂), after 6 weeks of wash-out (T₃), and after a further 6 weeks of plyometrics (T₄). Subjects were divided into pre- and post- peak-height-velocity (PHV) groups, and were randomly assigned to 30 s or 120 s inter-set intervals during periods T₂ and T₄. Any changes in jumping and maximum kicking velocities during T₁ and T_3, had trivial effect sizes (0.01–0.15), but small to moderate improvements (effect size = 0.20–0.99) were observed in both groups during T₂ and T₄. Gains in pre-PHV players were similar for the two inter-set intervals, but gains in post-PHV players were greater (p < 0.05) with an inter-set recovery of 120 s than with a 30 s recovery. We conclude that plyometric jump training improves the physical fitness of adolescents, irrespective of their maturity, but that in older individuals gains are greater with a longer inter-set recovery interval.  相似文献