排序方式： 共有66条查询结果，搜索用时 15 毫秒
61.
Rachna Agarwal Sangeeta Sharma Neelam Chhillar Kiran Bala Neeraj Singh C. B. Tripathi 《Indian journal of clinical biochemistry : IJCB》2009,24(4):366-369
The present study was conducted to assess correlation of ammonia levels with valproate levels in epileptic patients presenting
with valproate toxicity and also whether liver enzymes and ammonia levels could serve as biochemical marker of valproate toxicity.
100 patients with epilepsy who had received valproate therapy for more than 12 months and had presented with valproate toxicity
and 100 controls were included in the study. The serum valproate, ammonia and liver enzymes were measured in these subjects.
In patients with valproate toxicity, the mean level of serum valproate was 110.91 ± 28.68 mg/dL (therapeutic range 50–100
mg/dL). Serum ammonia was higher (86.37 ± 39.90 μg/dL) in patients with valproate toxicity compared to controls (68.73 ± 30.07
μg/dL). Out of 100 patients, only 37 patients had serum valproate level > 120 mg/dL and 22 patients had raised levels of valproate
as well as ammonia. Age < 30 years and serum ammonia > 69 μg/dL is risk factors for valproate toxicity. Serum ammonia, liver
enzymes should be regularly investigated in patients on valproate therapy for early diagnosis of valproate toxicity. 相似文献
62.
A. Dasgupta J. K. Agarwal S. S. Dubey 《Indian journal of clinical biochemistry : IJCB》1992,7(1):33-36
The aim of the present study was to evaluate the serum levels of lecithin cholesterol acyl transferase and lipoprotein cholesterol in hyperthyroid patients. The serum levels of total cholesterol and triacylglycerols were also determined in order to assess the lipid status of these patients. It was observed that serum content of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density liproprotein cholesterol (HDL-C) were significantly lower (P<0.001) in these patients whereas serum triacylglycerols (Tg.) and very low density lipoprotein cholesterol (VLDL-C) (P>0.05) did not show any significant change as compared to control values. However, the serum level of lecithin cholesterol acyl transferase (LCAT) was significantly higher (P<0.001) in these patients. It is concluded that an increased LCAT activity plays a significant role in regulating lipoprotein cholesterol levels in hyperthyroid patients. 相似文献
63.
Mirna E. Turcios Naresh Kumar Agarwal Linda Watkins 《The Journal of Academic Librarianship》2014,40(5):473-479
There is an extensive amount of Library and Information Science (LIS) writing produced each year. While there is general awareness regarding the variety of journal literature, there is no certainty on the percentage of the collection that we can call research. This project is an important first step in answering the question. A content analysis of the LIS academic/scholarly journals at the Simmons College Library was conducted. The research level collection of LIS literature makes the library an ideal candidate for this study. The latest issue of each journal subscribed to for fiscal year 2012–2013 containing academic/scholarly content was analyzed. Each article was analyzed to determine: 1) if it was research or non-research, 2) the method used to collect data for the study in the article, and 3) the subject terms or keywords associated with the article. 105 journal titles were identified out of 177 periodicals. In the 1880 articles analyzed from these, 16% qualified as research. Surveys were found to be the most popular research method used. This study will benefit students, faculty, and staff with research requirements as well as librarians who guide patrons through a search for research literature. 相似文献
64.
In this paper, within the framework of ordinary differential equation and eutrophication ecological theory, long-run sustainability of an impulsive switched eutrophication controlling system based upon the Zeya reservoir is studied analytically and numerically. A key advantage of the impulsive switched eutrophication controlling system is that it can be quite accurate to better describe the influence mechanism of some key factors during eutrophication controlling process, which enables a systematic and logical procedure for fitting eutrophication system to real monitoring data. Mathematical theoretical works have been pursuing the investigation of some conditions for all species persistence, which can deduce a standard parameter control relationship and in turn can provide a theoretical basis for the numerical simulation. Numerical analysis indicates that the theoretical results are correct and the long-run substainability of the impulsive switched eutrophication controlling system mainly depends on some critical parameters. It should also be stressed that the values of some critical parameter can be determined by a standard parameter control relationship. In addition, it is successful to show that the standard parameter control relationship maybe be used as an explicit threshold function to judge the long-run sustainability of eutrophication controlling process for the Zeya reservoir. Finally, all these results are expected to be of use in the study of the dynamic complexity of eutrophication ecosystems. 相似文献
65.
Rashmi G. Shukla Anuja Agarwal Vidhu Shekhar 《The Journal of High Technology Management Research》2021,32(2):100415
Indian Healthcare system is a complex and distinguished structure due to variety of factors viz. population size it serves, presence of organized and unorganized services of healthcare, economic disparity and governance structure among others. Extant research emphasizes on the aspects like transparency, trust, disintermediation, non-repudiation, benchmarking of processes and practices, traceability and data integrity among others to stimulate the Indian Healthcare system for an improvised and more effective format. Blockchain Technology is recent innovation that offers many of these aforementioned aspects as a feature to the host systems. However, it is critical to understand and articulate the utility of Blockchain Technology specific to the Indian Healthcare system. Further, it is important to gauge the requirement elicitation of key stakeholders for Blockchain Technology adoption in Indian Healthcare system w.r.t any attribute prioritization/customization or design considerations (Consensus mechanism, type of blockchain, smart contracts etc.). There have been some research works on aspects of Blockchain applications in Indian Healthcare but lack a strong perspective of stakeholder requirements. We use Value-Focused Thinking framework based on discussions with the stakeholders to address the above mentioned research premise. We identify Fundamental Objectives and Strategic Objectives from the stakeholder interactions that contribute to the strategic goal. This is a niche work with a significant analytical contribution from the information systems perspective of Blockchain Technology adoption in the Indian Healthcare ecosystem given the light of premises from realms of human agents, behavioural and applications requirement from a stakeholder viewpoint. 相似文献
66.
Ashish Agarwal Anupama Hegde Charu Yadav Afzal Ahmad Poornima Ajay Manjrekar Rukmini Mysore Srikantiah 《Indian journal of clinical biochemistry : IJCB》2017,32(1):33-38
Impaired fasting glucose (IFG) is a high risk subclinical condition for the progression of type 2 diabetes mellitus and the hyperglycemia seen in this condition is because of the development of insulin resistance (IR). Obesity, inflammation, oxidative stress and many other factors have been implicated in development of IR in type 2 diabetes mellitus and its successive complications. Current study was aimed to ascertain the correlation of inflammation and oxidative stress markers [interleukin-6 (IL-6) and myeloperoxidase (MPO)] with IR in subjects with IFG. In this study, 80 subjects (40 IFG, 40 healthy controls) aged 25–45 years were selected based on their fasting plasma glucose (FPG) values and clinical history. Serum insulin, IL-6 and MPO were estimated by ELISA method and IR was calculated using Homeostatic Model Assessment Index 2 (HOMA 2) calculator. Pearson’s correlation coefficient and independent sample ‘t’ test were used for statistical analysis. IL-6 and MPO were found to be significantly elevated in IFG group and both correlates significantly with IR (r 0.413, r 0.645). Only MPO had significant correlation with FPG (r 0.388). In conclusion, the association of altered levels of IL-6 and MPO with IR are suggestive of a role of inflammation and oxidative stress in the initiation and progression of IR in individuals with IFG. 相似文献