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This paper reports the results of a qualitative study on the process of learning complex concepts in chemistry by four students
as they worked with FLiPS (Flexible Learning in the Periodic System), a cognitive flexibility multi-media hypertext for learning
about the periodic system of elements. A wide range of probes (think-alouds; navigation logs; observational notes, interviews;
pre- and post-tests; epistemic beliefs survey; and background questionnaire) produced a rich data set for analysis. This data
was analyzed to construct rich narrative case- and cross-case narratives of the participants' process of working and learning
in this complex hypertext environment. This multi-level analysis offers insight both into the fine-grained process of use
as well as the larger issues of the pedagogical significance of FLiPS. Our analysis reveals a complex relationship between
epistemic beliefs, student motivation, prior knowledge, and process of learning from hypertext. We offer implications for
future research, design and the application of pedagogical hypertexts.
Requests for reprints should be sent to Punya Mishra, Learning, Technology, and Culture Program, Michigan State University,
509A Erickson Hall, East Lansing, MI 48824. E-mail: punya@msu.edu 相似文献
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K. K. Mishra H. P. Pandey R. H. Singh 《Indian journal of clinical biochemistry : IJCB》2007,22(2):41-43
Present clinical study involved two groups of psychosomatic disorders, bronchial asthma and rheumatoid arthritis. In the study,
the levels of plasma cortisol, blood glucose, total cholesterol and triglycerides were estimated in 125 clinical subjects,
(50 normal controls, and 40 having bronchial asthma and 35 suffering from rheumatoid arthritis. The results showed a significant
change in the levels of plasma cortisol and blood glucose in both the stressed clinical groups' vis-à-vis normal controls.
The levels of atherogenic lipids (total cholesterol and triglycerides) were found quite elevated in both the diseased groups.
However, in rheumatoid arthritis, the physiological changes were relatively more pronounced. The findings of this study indicate
that rheumatoid arthritis is a relatively more chronic and late onset disorder as the functional performance of hypothalamopituitary-adrenocortical
axis gradually declines with passage of time and the ability of the adrenocortical response to return to normalcy becomes
impaired. 相似文献
147.
Sarita Chavan Laxmayya Sava Vishal Saxena Sandhya Pillai Alka Sontakke Digamber Ingole 《Indian journal of clinical biochemistry : IJCB》2005,20(1):150-152
Glutathione, the dominant intracellular thiol, plays an important protective role against oxidative stress. The accidental
findings of increased reduced glutathione level postprandially as compared to post absorptive level prompted the design of
present study. Reduced Glutathione levels were estimated in 50 healthy individuals in post absorptive and postprandial phase
by taking whole blood in ACD bulb. Mean postprandial reduced Glutathione (9.60±3.39 μmole/gm of Hb) is significantly increased
than mean postabsorptive level (5.53±0.88 μmole/gm of Hb; p<0.001). It also shows positive correlation (r=0.65) between these
two GSH levels. So present study suggests that post absorptive specimen collection is preferable over random or postprandial
as the former reflects the true basal level of reduced glutathione. 相似文献
148.
S. K. Mathur Piyush Chandra Sandhya Mishra Peeyush Ajmera Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2007,22(2):70-73
Asian Indians are known to be at a higher risk of developing T2DM, but the underlying genetic factor in this population is
still not well understood. T2DM is a complex genetic trait and assessment of disease related intermediate phenotypic traits
is an important initial step towards any systematic genomic study. Therefore, in the present study we have assessed diabetes
related intermediate phenotypic traits of insulin secretion and insulin resistance in the patients belonging to this population.
The study included 157 T2DM patients of either sex ranging in age from 45–80 years and 84 non-diabetic subjects with no family
history of diabetes, ranging in age from 45 to 75 years served as controls. Intermediate phenotypic traits studied were BMI,
W: H ratio, fasting free fatty acid level and Insulin resistance and secretion. Diabetics were found to have significantly
higher W: H ratio (p<0.001), FFA (p<0.001) and HOMA-R (p<0.001) as compared to non-diabetics. However, there was no significant
difference in their BMI and HOMA-β. There was a positive correlation between FFA level and HOMA-R among diabetics, but not
among controls. These findings suggest that in abdominal obesity FFA mediated insulin resistance is an important causative
factor underlying T2DM in this population. Moreover, comparable HOMA-β in diabetics reflects compensatory insulin hyper secretion
in these subjects. There is a need to examine relative contribution and precise nature of genetic factor in their tendency
for central obesity, free fatty acidemia and insulin resistance. 相似文献
149.
This study was carried out to estimate the levels of glutathione peroxidase and selenium in blood of abortion cases. Glutathione
peroxidase and selenium were determined in 52 abortion cases (22 in 1st trimester, 30 in second trimester), 45 normal pregnant cases and 25 nonpregnant control cases. The selenium concentration
in whole blood and plasma in abortion cases was almost the same as in normal pregnant women but significantly low when compared
with the control non-pregnant group. The glutathione levels was higher in abortion cases when compared with normal pregnant
and non-pregnant control groups. Red cell and plasma glutathione peroxidase activities of women who had abortion were significantly
lower compared with both non-pregnant control group and normal pregnancies. 相似文献
150.
ABSTRACTExtracurricular student–staff partnership activities are increasingly common in higher education institutions, but concerns have been expressed about their relative inclusivity. In order to contribute to understanding of why students do and do not take part in such initiatives, this study draws on data from a survey of students at four institutions, in three different countries, with established extracurricular partnership programs. Though the findings indicate some preliminary differences between participants at the four institutions, they also demonstrate a number of shared perceptions, including similar understandings of key features of partnership and shared perceptions of barriers to participation. Implications for partnership practice and research are discussed. 相似文献