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Ricardo Colomo-Palacios Cristina Casado-Lumbreras Pedro Soto-Acosta Sanjay Misra 《Interactive Learning Environments》2014,22(2):221-240
The use of Web 2.0 technologies for knowledge management is invading the corporate sphere. The Web 2.0 is the most adopted knowledge transfer tool within knowledge intensive firms and is starting to be used for mentoring. This paper presents IM-TAG, a Web 2.0 tool, based on semantic technologies, for informal mentoring. The tool offers recommendations of mentoring contents built upon personal competencies of the mentee, combined with content and opinion tagging. To validate the tool, a case study comparing recommendations from the IM-TAG and a group of experts was conducted. Results show that the accuracy of IM-TAG's recommendations is notable and satisfactory. The main conclusions of this research may be valuable to organizations immersed in mentoring programs. 相似文献
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R. Kapoor D. B. Gundpatil B. L. Somani T. K. Saha S. Bandyopadhyay P. Misra 《Indian journal of clinical biochemistry : IJCB》2014,29(2):213-220
Cancer cells generally exhibit increased glycolysis for ATP generation (the Warburg effect). Compounds that inhibit glycolysis have potential applications in cancer treatment. dl-glyceraldehyde (DLG) and 2-Deoxyglucose (2-DG) have been proven effective in the inhibition of glucose metabolism. Ehrlich ascites carcinoma (EAC) cells were injected intraperitoneally (i.p) in 10–12 weeks old Swiss albino mice, weighing between 20 and 30 g. The anticancer activity of DLG and 2-DG were determined by tumor volume, tumor weight, viable and nonviable tumor cell count, average survival time, percentage increase in life span and tumor inhibition ratio. The blood samples were obtained for biochemical analysis after 9 days of treatment to study the effect on liver, kidney and haematological parameters. Histopathological examination of liver and kidney was also performed. One-way ANOVA test and Dunnett’s test were used for comparisons of parameters in study groups. Both DLG and 2-DG individually decreased the tumor weight, tumor volume, viable tumor cell count and significantly increased the life span of treated mice, however the combination was found to be better. The biochemical parameters of liver and kidney functions and haematological parameters were restored close to control group as compared with the EAC bearing mice. Histopathological examination of liver and kidney in EAC control group showed large areas of necrosis, congestion and mononuclear cell infiltration but such changes were not observed in liver and kidney sections observed after i.p injection of DLG and 2-DG for 9 days. Improvement was much better in the group where combination of these two drugs were used. 相似文献
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Michelle Rodrigues Nina Sokolovic Sheri Madigan Yiqi Luo Victoria Silva Shruti Misra Jennifer Jenkins 《Child development》2021,92(2):554-577
In a series of meta-analyses, paternal sensitivity was associated with children’s (age range: 7 months–9 years) overall cognitive functioning (N = 3,193; k = 23; r = .19), including language skills (k = 9; r = .21), cognitive ability (k = 9; r = .18), and executive function (k = 8; r = .19). Paternal sensitivity was not associated with children’s overall socioemotional functioning (N = 2,924; k = 24; r = −.03) or internalizing problems, but it was associated with children’s emotion regulation (k = 7; r = .22) and externalizing problems (k = 19; r = −.08). In the broad cognitive functioning, executive function, broad socioemotional functioning, and externalizing problems meta-analyses, child age was a significant moderator. 相似文献
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Colloids play an important role in our modern lives. In this article, we briefly discuss various forces that are known to operate between colloidal particles and then take the reader through the discovery of a new, strong and long ranged force operating between hydrophobic particles/surfaces. Characteristics of the new force and some promising theories proposed in the literature to explain its origin are also discussed; the origin of the new force is not yet resolved, however. 相似文献
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P.K. Misra 《Educational Media International》2013,50(2):109-122
The changing landscape of learning is helping Asian countries to emerge as technology-driven knowledge-based societies. The success of these societies depends on promoting the acquisition of key competences and broadening opportunities for innovative and more flexible forms of learning for every citizen. Considering that in Asia almost everyone has a mobile phone or will have a mobile phone soon, the author argues that Asian countries can establish and use mobile networks for lifelong learning. The researcher proposes each-one-teach-one mobile networks as an innovative knowledge-access strategy, particularly for Asian countries and in general for all the countries across the globe. The proposed mobile networks will work on the principle that those who want to teach and those who want to learn must have a free and open service to get connected for knowledge sharing. 相似文献
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Manorama Swain Preetam Nath Prasant Kumar Parida Jimmy Narayan Pradeep Kumar Padhi Girish Kumar Pati Ayaskanta Singh Bijay Misra Debasis Misra Sanjib Kumar Kar Manas Kumar Panigrahi Chudamani Meher Omprakash Agrawal Niranjan Rout Kaumudee Pattnaik Pallavi Bhuyan Pramila Kumari Mishra Shivaram Prasad Singh 《Indian journal of clinical biochemistry : IJCB》2017,32(3):306-314
Aminotransferase assay is often used as a screening test as well as an endpoint for resolution of disease in nonalcoholic fatty liver disease (NAFLD). Aim of the study was to evaluate the relationship of transaminase level with metabolic variables and histology in NAFLD. Single center observational study was conducted in a gastroenterology clinic at Cuttack in coastal Odisha. Subjects were consecutive patients presenting with functional bowel disease and undergoing abdominal sonography. All participants were evaluated for the presence of metabolic syndrome (MS), insulin resistance, liver function test and lipid profile. Various parameters were compared between NAFLD subjects and controls. 53.5 % of NAFLD had normal serum transaminases, whereas 20.8 % of healthy controls had transaminitis. NAFLD patients had significantly higher BMI, fasting plasma glucose, serum transaminases, serum triglycerides, serum insulin and homeostatic model assessment (HOMA) IR than controls. NAFLD patients who had transaminitis had significantly higher incidence of MS and higher mean HOMA IR than those without. There was no significant difference in histopathological features between NAFLD with and without transaminitis. To conclude, over half of NAFLD subjects do not have transaminitis while transaminitis is present in a fifth of healthy people without fatty liver. Hence serum transaminase should not be used as screening test for NAFLD. NAFLD patients with transaminitis had a higher incidence of MS and insulin resistance than those without. However, there was no significant difference in histopathological features between these two groups. 相似文献
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Chetna Bhatt Zarangis Misra Neelam Goyel 《Indian journal of clinical biochemistry : IJCB》2008,23(1):10-16
Mental Retardation is a condition where complex interactions of intrinsic and extrinsic factors hamper mental and sometimes
physical growth of the child during developmental period. This study was carried out to detect cause of Mental Retardation
in 2000 cases of developmental delay by a multidisciplinary team comprising of a Pediatrician, Cytogeneticist, Biochemist,
Psychologist and Speech and Occupational therapists. The causes for developmental delay are broadly divided into Genetic,
Environmental and Idiopathic (no specific cause found) factors. The complete diagnosis was possible in 1192(60%) cases. Genetic
factors were found in 477(23.8%) cases and environmental factors covered 692(34.6%) cases as a cause of retardation. The most
common genetic cause is chromosomal abnormalities which were found in 355 (17.75%) cases. Another major group comprising of
122 (6.1%) cases was that of the disorders which follow Mendelian inheritance. Autosomal recessive conditions, which covers
majority of metabolic disorders, are detected in 48(2.4%) cases. During this screening the most common inherited metabolic
condition detected is Mucopolysaccharidosis, a Lysosomal Storage Disorder followed by Amino acid abnormalities like Phenylketonuria,
Alkaptonuria and Tyrosinuria. 相似文献
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