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11.
Resource-sharing normally follows a network of libraries with decent rules and regulations and provides a common platform for libraries and library staffs to come together, communicate, and extend help to enhance access to information and fulfill the unexpected demands of users. This article studies the use of interlibrary loan and document delivery service at the Information and Library Network Centre under the UGC-Infonet Digital Library Consortium program. Universities that come under the purview of the University Grants Commission (UGC), Government of India, become members of UGC-Infonet Digital Library Consortium. The article discusses the recent literature on resource-sharing through interlibrary loan and document delivery service practice in the Indian context. This article suggests improvement of J-Gate Plus discovery and resource-sharing service to enhance access to information resources and for better document delivery.  相似文献   
12.
A 50 year old male was admitted in our hospital with anemia and impaired renal function. He was subsequently found to have extremely elevated serum phosphate level (24 mg/dL, reference interval: 2.5–4.5 mg/dL) with normal serum calcium when assayed on a Beckman Coulter AU 480® analyser. Clinico-biochemical discrepancy led to the suspicion of spurious hyperphosphatemia. Serum total protein was grossly elevated with gross reversal of albumin to globulin ratio. Serum electrophoresis revealed a large M band and was confirmed as Ig G-Kappa type on immunofixation. Subsequently a bone marrow aspiration biopsy confirmed the diagnosis of multiple myeloma. The patient serum was then reassayed for phosphate on a Vitros® 250 Dry Chemistry platform and the result was within normal reference interval. Paraproteinemias are a common cause of analytical interference in clinical biochemistry laboratories and as multilayered film technology platforms like Vitros® assay most routine analytes on a protein free filtrate they are unaffected by paraprotein interference. Clinically discordant patient results should always be interpreted keeping such interferences in mind.  相似文献   
13.
Hyperglycemia and dyslipidemia in diabetes mellitus induce increased lipid peroxidation and peroxyl radical formation, an important mechanism in genesis of microangiopathy. We took up a study on oxidative stress, measured by plasma MDA and antioxidant vitamin status in type − 2 DM patients with and without retinopathy and compared them with a control non-diabetic group. Lipid peroxidation marker MDA was significantly elevated (p < 0.001) in both the diabetic groups whereas, serum vitamin E and vitamin C registered a significant fall (p<0.001) as compared to controls. Our correlation study revealed a significant positive association between plasma MDA with both fasting and 2hr post prandial plasma glucose (r=0.81, p < 0.001, r=0.92, p <0.001) suggesting the role of hyperglycemia in free radical production. Plasma MDA also depicted significant positive relation (p< 0.001) with all lipid parameters except serum HDLc pointing the role of dyslipidemia towards lipid peroxidation. Plasma MDA level was also found to be negatively correlated with both the vitamins (p<0.001, p<0.001) in the study group explaining their protective consumption in the oxidative process prevailing in diabetic retinopathy.  相似文献   
14.
本文主要阐述了当代远程学习的变化特征,其中包括学习的情境化、学习共同体与实践者共同体的结合、混合培训的运用等;同时,本文还对传统远程学习和现代在线学习环境下的课程设计和开发的各种模式进行了介绍.本案例中,学习资源的设计主要分为三个模块,即存在的技能、持续性的更新,以及全球化技能的发展.结合中小企业本身特点以及上述所提及的方面,为我们发展和清晰地表达一个中小企业持续性专业发展的框架奠定了基础.通过这个框架,在线学习共同体与离线的实践者共同体相结合,可以促进在某一特定文化背景下人们专业认同度和实践水平的提高.  相似文献   
15.
Following initial scepticism, the growth and developments within distance education in India have been tremendous. This paper records those developments in one of the largest distance education systems in the world with regard to its contribution to national development. The paper also examines curricular programmes, access and equity, media and technology, funding and costing, quality and accreditation, collaboration and networking, internationalization, and outcomes and benefits. The paper argues that higher education at a distance has significantly contributed to Indian national development on various counts, including innovative programmes for niche markets as well as community development; nation‐wide training programmes for the workforce and community and the empowerment of women; information and communications technology (ICT) networking and sharing of resources; massive human resource development for IT; management; school teaching; and development in new sectors of the workforce. Nevertheless, the areas of quality of instructional processes, access and equity, and effective deployment and use of ICT have been highlighted as accelerators to the system in its future expansion.  相似文献   
16.
An investigation was undertaken to study the composite effect of a package of certain curricular strategies on some cognitive and non‐cognitive characteristics of rural primary school students. The present article lists the results pertaining to one variable, i.e. study habits. The sample consisted of three groups of class V students. One group was taught using the package programme while the other two were given instruction through their regular teachers found to teach without the effective use of selected curricular strategies. The results indicated that the experimental group exhibited a significantly increased level of study habits in comparison to control group I and control group II while the two control groups exhibited an equal level of study habits. Further, the experimental and control group I exhibited a significantly increased level of study habits at the end of the academic session as compared to the beginning of the session whereas there was no significant change in the level of study habits of control group II.  相似文献   
17.
This work was undertaken to investigate correlation between oxidative stress and initiation of pathogenesis of pregnancy induced hypertension (PIH). Fifty primigravidae in age group of 20–35 years and gestational age 28–42 weeks with PIH were taken as cases. Twenty healthy primigravidae with no medical and surgical complications of pregnancy and with blood pressure ≤140/90 mm Hg served as controls. The cases were again subgrouped as severe preeclampsia (12 in number) and mild pre-eclampsia (38 in number). All of them were evaluated for serum malondialdehyde (MDA), Serum vitamin E and plasma vitamin C levels. The serum MDA levels were raised significantly in women with mild preeclampsia (P<0.01) and in women with severe preeclampsia (P<0.01) in comparison to normal primi gravida. The serum vitamin E levels were decreased in primi gravida with mild preeclampsia (p<0.1) and in primi with severe pre eclampsia (P<0.1) in comparison to normal primi gravida but the fall was not statistically significant. There was a significant fall (P<0.05) in the vitamin C levels in primi with mild preeclampsia than in the normal primi. The vitamin C levels in severe preeclamptic patients were lower than the normal primi but the fall was not statistically significant (P=0.10). The serum MDA and vitamin E showed a negative correlation in all the cases. The serum MDA and plasma vitamin C also showed a negative correlation in the control and study group. This observation suggests that in hypertensive disorders of pregnancy there is an imbalance between lipid peroxidation and antioxidant vitamin status because of oxidative stress. The decreased serum concentrations of the antioxidant vitamins supports the hypothesis that lipid peroxidation is an important causative factor in the pathogenesis of preeclampsia. The rise in antioxidants is probably to compensate the increased peroxide load in severe preeclampsia.  相似文献   
18.
Serum malondialdehyde was measured in sixty-one falciparum malaria cases, which include thirty uncomplicated, and thirty-one complicated with acute renal failure. Twenty-six healthy individuals were also studied as controls. Serum malondialdehyde level was found to be significantly elevated in falciparum malaria induced acute renal failure cases when compared with uncomplicated falciparum malaria (p<0.001) and healthy controls (p<0.001). A positive correlation with the raised urea, creatinine and bilirubin levels were significant (r=0.62, p<0.025; r=0.65, p<0.05 and r=0.72, p<0.001 respectively) indicating the severity of complication with rise of lipid peroxides in falciparum malaria induced acute renal failure cases.  相似文献   
19.
The optimal location of a static synchronous compensator (STATCOM) and its coordinated design with power system stabilizers (PSSs) for power system stability improvement are presented in this paper. First, the location of STATCOM to improve transient stability is formulated as an optimization problem and particle swarm optimization (PSO) is employed to search for its optimal location. Then, coordinated design problem of STATCOM-based controller with multiple PSS is formulated as an optimization problem and optimal controller parameters are obtained using PSO. A two-area test system is used to show the effectiveness of the proposed approach for determining the optimal location and controller parameters for power system stability improvement. The nonlinear simulation results show that optimally located STATCOM improves the transient stability and coordinated design of STATCOM-based controller and PSSs improve greatly the system damping. Finally, the coordinated design problem is extended to a four-machine two-area system and the results show that the inter-area and local modes of oscillations are well damped with the proposed PSO-optimized controllers.  相似文献   
20.
Power-system stability improvement by a static synchronous series compensator (SSSC)-based damping controller is thoroughly investigated in this paper. Both local and remote signals with associated time delays are considered in the present study. The design problem of the proposed controller is formulated as an optimization problem, and differential evolution (DE) algorithm is employed to search for the optimal controller parameters. The performances of the proposed controllers are evaluated under different disturbances for both single-machine infinite-bus power system and multi-machine power system. The performance of the proposed controllers with variations in the signal transmission delays has also been investigated. Simulation results are presented and compared with a recently published modern heuristic optimization technique under various disturbances to show the effectiveness and robustness of the proposed approach. The performances of the proposed controllers are also evaluated under N−2 contingency situation.  相似文献   
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