Gene Editing in Clinical Practice     

Rama Devi Mittal 《Indian journal of clinical biochemistry : IJCB》2018,33(1):1-4

  相似文献   

Influence of learning techniques on information processing     

Cittoor Girija Navaneedhan K. Saraladevi Devi 《美中教育评论》2009,6(1):24-35

The present study establishes the fact that effective information processing is dependent on the learning techniques one adopts. A sample of 100 students in the age group from 13 to 17 including boys and girls were chosen. They were divided into two groups of control and experimental. To the experimental group, certain specific learning techniques were taught for a period of six months. The same group was tested taking blood samples to study the neuro transmitter serotonin levelshenme before and after adopting learning techniques. Results of the study proved that there is significant relationship between learning techniques and the information processing ability of an individual.  相似文献   

Genetic Variation in <Emphasis Type="Italic">CD166</Emphasis> Gene and Its Association with Bladder Cancer Risk in North Indian Population     

Archana Verma  Rakesh Kapoor  Rama Devi Mittal 《Indian journal of clinical biochemistry : IJCB》2017,32(3):292-300

Adhesion molecules play a key role in cancer progression and tumorigenesis. Genetic polymorphism of adhesion molecules may alter the normal functioning thereby leading to bladder cancer susceptibility. Hence we aimed to evaluate three SNPs of CD166 gene (CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G) in bladder cancer patients and normal controls of North Indian population. A total of 270 healthy controls and 240 confirmed bladder cancer patients were recruited for this study. Three SNPs of CD166 gene viz. CD166rs6437585 C/T, CD166rs10511244 C/T, and CD166rs1157 A/G were selected for this study. CD166rs6437585 C/T and CD166rs10511244 C/T were genotyped by Taqman allelic discrimination assay and CD166rs1157 A/G was genotyped by PCR–RFLP. The statistical analysis was done using the SPSS software, version 16.0 (SPSS, Chicago, IL), and p < 0.05 was considered statistically significant. Haplotypic analysis was done by using SNP analyzer version 1.2A. CD166rs6437585 C/T and CD166rs10511244 C/T showed significant association with reduced risk in bladder cancer while CD166rs1157 A/G showed significant high risk along with association at genotypic and allelic levels. Haplotypic analysis showed 1.8-folds risk in CCG combination, whereas CTA and TCG showed significant association with reduced risk. Further stratification on the basis of smoking, tumor grade/stage and BGC therapy revealed no association of these three polymorphic sites of CD166. Our study suggests that CD166rs6437585 C/T and CD166rs10511244 C/T are predictive for the reduced risk of bladder cancer, whereas CD166rs1157 A/G had shown significant association with high risk of bladder cancer in North Indians. This somehow suggests that CD166rs1157 A/G can be used as a marker for risk prediction of bladder cancer.  相似文献   

Aflatoxins: Implications on Health     

Usha P. Sarma  Preetida J. Bhetaria  Prameela Devi  Anupam Varma 《Indian journal of clinical biochemistry : IJCB》2017,32(2):124-133

Environmental occurrence of Aspergillus and other fungal spores are hazardous to humans and animals. They cause a broad spectrum of clinical complications. Contamination of aflatoxins in agri-food and feed due to A. flavus and A. parasiticus result in toxicity in humans and animals. Recent advances in aspergillus genomics and aflatoxin management practices are encouraging to tackle the challenges posed by important aspergillus species.  相似文献   

Writing retreats as a milestone in the development of PhD students’ sense of self as academic writers     

Uta Papen  Virginie Thériault 《Studies in Continuing Education》2018,40(2):166-180

Writing retreats are structured events during which a group of people write in the same room over several days. In this paper, we report on findings from a study exploring the impact of writing retreats on PhD students’ writing and their sense of self as academic writers. A second aim of the study was to contribute to the search for appropriate pedagogies to support writing at the PhD level. The data consist of interviews with 19 PhD students who had taken part in writing retreats as well as evaluations and pre- and post-retreat reflections by these students. In the interviews, we discussed the role of writing retreats in the context of the students’ wider biographies as writers and how it relates to their experiences of writing. Our findings suggest that writing retreats can be important events for PhD students positively affecting their relationship with literacy [Besse, J.-M. 1995. L’écrit, l’école et l’illettrisme. Paris: Magnard]. Taking part in a retreat generates pleasure, emphasising the role of emotions in academic writing. Writing retreats and the opportunities they offer students to write and to reflect on their experiences as writers are a valuable part of PhD training.  相似文献   

Phase-based information retrieval     

A.T. Arampatzis  T. Tsoris  C.H.A. Koster  Th.P. van der Weide 《Information processing & management》1998,34(6):693-707

In this article we describe a retrieval schema which goes beyond the classical information retrieval keyword hypothesis and takes into account also linguistic variation. Guided by the failures and successes of other state-of-the-art approaches, as well as our own experience with the Irena system, our approach is based on phrases and incorporates linguistic resources and processors. In this respect, we introduce the phrase retrieval hypothesis to replace the keyword retrieval hypothesis. We suggest a representation of phrases suitable for indexing, and an architecture for such a retrieval system. Syntactical normalization is introduced to improve retrieval effectiveness. Morphological and lexico-semantical normalizations are adjusted to fit in this model.  相似文献   

The exile of the Jews in Babylon     

Margaret Avery S.Th. 《British Journal of Religious Education》1938,5(1):40-48

  相似文献   

Federation of University Women's ‘Camps’ for Schoolgirls     

Violet Wilkinson N.F.U. S.Th. 《British Journal of Religious Education》1937,4(3):165-166

  相似文献   

Book reviews     

Franklin Parker  William W. Brickman  Tadeusz J. Wiloch  Enno Schmitz  Otto Roloff  John Raven  Eric Hoyle  Gerd Doerry  Walter Hahn  Hans Weiler  Richard Cummings  A. G. Hearnden  Gerd Iben  E. K. Townsend Coles  A. Harry Passow  Françoise Bacher  Alexandre Vexliard  Thành Lê Khôi  Doris Elbers  Brigitte Beer 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》1971,17(4):469-504

  相似文献   

Modelling students' construction of energy models in physics     

Roshni Devi  Andrée Tiberghien  Michael Baker  Paul Brna 《Instructional Science》1996,24(4):259-293

One of the main differences between novice and expert problem solving in physics is that novices mostly construct problem representations from objects and events in the experimental situation, whereas experts construct representations closer to theoretical terms and entities. A main difficulty in physics is in interrelating these two levels, i.e. in modelling. Relatively little research has been done on this problem, most work in AI, psychology and physics education having concentrated on how students use representations in problem solving, rather than on the complex process of how they construct them. We present a study that aims to explore how students construct models for energy storage, transformation and transfers in simple experimental situations involving electricity and mechanics. The study involved detailed analysis of problem solving dialogues produced by pairs of students, and AI modelling of these processes. We present successively more refined models that are capable of generating ideal solutions, solutions for individual students for a single task, then models for individuals across different tasks. The students' construction of energy models can be modelled in terms of the simplest process of modelling — establishing term to term relations between elements of the object/event world and the theory/model world, with underlying linear causal reasoning. Nevertheless, our model is unable to take into account more sophisticated modelling processes in students. In conclusion we therefore describe future work on the development of a new model that could take such processes into account.1. CHENE = CHaîne ENErgetique, or Energy Chain. (In French Chêne also means oak).2. Throughout the rest of the paper we use the following simple notation in order to avoid possible confusion between modelling as a process performed by the students, in the domain of physics, and AI modelling of the former modelling process: students' modelling in physics = modelling _SP ; AI modelling (of modelling _SP ) = modelling _AI .3. It has not been necessary to use more sophisticated strategies at the stage of our work reported here. The next system, modelCHENE, will directly address this issue.4. Note that what we refer to in this context as problem solving may in another context be viewed as construction of a qualitative representation for subsequent quantitative problem solving.5. The protocols indicate that students use this as a kind of anchor in their reasoning-some students returning to it in order to resolve impasses. As the current problem solver provides no mechanism for handling impasses we cannot model the reuse of information in any meaningful way.6. We are grateful to an anonymous reviewer for this example.7. This provides the minimum distinction for our initial needs.8. Though there is a difficult step in deciding that the moving object really is the last unassigned object-since that requires setting aside any need to assign roles to, for example, connecting strings etc.9. At the moment we have to provide psCHENE with slightly different rulesets: providing rules with priorities would be more convenient.  相似文献