Noise and fluctuations in electronic devices and circuits: F. N.H. Robinson. 246 pages,diagrams, 6×9 in. Oxford,England, Clarendon Press, 1974. Price, $27.25.     

Madhu S. Gupta 《Journal of The Franklin Institute》1977,303(2):220-221

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Hypoxia-Induced Inflammatory Chemokines in Subjects with a History of High-Altitude Pulmonary Edema     

K. P. Mishra  Navita Sharma  Poonam Soree  R. K. Gupta  Lilly Ganju  S. B. Singh 《Indian journal of clinical biochemistry : IJCB》2016,31(1):81-86

High altitude hypoxia is known to induce an inflammatory response in immune cells. Hypoxia induced inflammatory chemokines may contribute to the development of high altitude pulmonary edema (HAPE) by causing damage to the lung endothelial cells and thereby capillary leakage. In the present study, we were interested to know whether chronic inflammation may contribute to HAPE susceptibility. We examined the serum levels of macrophage inflammatory protein-1α (MIP-1α), monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 in group (1) HAPE Susceptible subjects (n = 20) who had past history of HAPE and group (2) Control (n = 18) consist of subjects who had stayed at high altitude for 2 years without any history of HAPE. The data obtained confirmed that circulating MCP-1, MIP-1α were significantly upregulated in HAPE-S individuals as compared to the controls suggestive of chronic inflammation. However, it is not certain whether chronic inflammation is cause or consequence of previous episode of HAPE. The moderate systemic increase of these inflammatory markers may reflect considerable local inflammation. The existence of enhanced level of inflammatory chemokines found in this study support the hypothesis that subjects with past history of HAPE have higher baseline chronic inflammation which may contribute to HAPE susceptibility.  相似文献   

Chemical composition of biliary calculi from Kanpur region     

S. K. Bansal  A. K. Gupta  A. Bansal  V. S. Rajput  L. D. Joshi 《Indian journal of clinical biochemistry : IJCB》1992,7(1):27-29

Gallstones from 24 female patients were subjected to quantitative chemical analysis. Two main categories of stones were identified: (1) Ten cholesterol stones with 93.38% cholesterol and only 0.17% bilirubin. (2) Mixed stones with cholesterol below 65%. They were sub-divided in two groups: (a) Six stones having 0.5% bilirubin and (b) Eight stones having 0.5% bilirubin. The calcium of cholesterol and mixed stones was comparable while phosphorus contents in cholesterol stones were low by over 30% in mixed stones.  相似文献   

Glycosylated haemoglobin-a diagnostic tool in pregnant diabetics     

N. Agarwal  U. Gupta  N. Kaul 《Indian journal of clinical biochemistry : IJCB》1996,11(1):62-65

Blood samples of 40 pregnant women were analysed for glycosylated haemoglobin (HbA1c) and blood sugar. The patients were followed up till delivery and their obstetric outcome was analysed in conjunction with the glycaemic profile and the level of glycosylated haemoglobin. Group I comprising the normal pregnant women showed a mean HbA1c of 6.23% at 20–40 weeks of gestation. In contrast the diabetic pregnant women (group II) at the same gestation demonstrated an HbA1c of 9.4%. Further group IIA of gestational diabetic women showed an HbA1c of 8.97% and group IIB comprising the overt diabetics had HbA1c of 9.86%. The mother who delivered a congenitally malformed child had an elevated HbA1c of 10.4% during pregnancy. Seven cases of macrosomia were reported and the mean HbA1c of their mothers at 20–40 weeks of gestation was found to be 9.91%. Six mothers delivered infants who developed respiratory distress syndrome (RDS) soon after birth and all these six had elevated HbA1c with a mean of 8.9%. Abortions were also associated with elevated HbA1c of 10.3% antenatally. One case of still birth was reported and the mother demonstrated an elevated glycosylated haemoglobin during pregnancy. An HbA1c of 10% or more was associated with abortion, still-birth, or congenitally malformed babies.  相似文献   

Phospholipid and cholesterol levels in serum and bile in cholelithiasis     

R. S. Kanwar  D. C. Merwaha  R. R. Gupta  P. S. Shukla  S. S. Minhas  S. Negi 《Indian journal of clinical biochemistry : IJCB》1996,11(2):173-175

Cholesterol and phospholipids were estimated in serum and bile from hepatic duct and gallbladder of twenty five patients of gallstone with functioning gallbladder (Group-I) and an equal number of patients having diseases other than of hepatobiliary system acting as control (Group-II). Group-I patients showed high serum cholesterol and low serum phospholipid levels as compared to those of Group-II. Cholesterol levels in hepatic duct and gallbladder bile were higher in Group-I than in Group-II whereas the phospholipid levels in the bile of Group-I were lower than in Group-II. The phospholipid: cholesterol ratios in hepatic duct and gallbladder bile of Group-I were 2.76 and 3.03 respectively as compared to 5.62 and 5.92 in Group-II.  相似文献   

Evaluation of the changes in serum iron levels in pre-eclampsia     

Shalini Gupta  Smiti Nanda  Uma Singh  Sadhna Bansal  Harbans Lal 《Indian journal of clinical biochemistry : IJCB》1997,12(1):91-94

Serum iron levels were studied in 50 patients with pre-eclampsia and the results were compared with 50 control cases. Their serum iron levels were found to be higher than the controls. Increase in serum iron was directly proportional to the increased levels of uric acid, urea and creatinine. Mean reticulocyte counts, plasma free haemoglobin and unconjugated bilirubin levels were also higher in these patients. It is suggested that haemolysis may be a major contributory factor for the increased levels of serum iron in pre-eclampsia.  相似文献   

A practical guide to needs assessment     

Kavita Gupta  Heekap Lee 《Performance Improvement》2001,40(8):40-42

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Regulation of metabolic pathways in liver and kidney during experimental diabetes: Effects of antidiabetic compounds     

Najma Zaheer Baquer  Dhananjay Gupta  Jayadev Raju 《Indian journal of clinical biochemistry : IJCB》1998,13(2):63-80

Diabetes has been classified as a disease of glucose overproduction by tissues, mainly liver and glucose underutilization by insulin requiring tissues like liver, adipose and muscle due to lack of insulin. There is, however, glucose over utilization in tissues not dependent on insulin for glucose transport like kidney, nerve and brain. There are serious complications due to this excess glucose in these tissues and their reversal is important for a good metabolic control and normalisation of other parameters. Insulin, trace metals and some plant extracts have been used to see the reversal effects of the complications of diabetes in liver and kidney in experimental diabetes. Almost complete reversal of the metabolic changes has been achieved in the activities of key enzymes of metabolic pathways in liver and kidney and an effective glucose control has been achieved suggesting a combination of therapies in the treatment of metabolic disturbance of the diabetic state.  相似文献   

Modelling the evolution of rates of ageing     

Vishal Gohil  Amitabh Joshi 《Resonance》1998,3(8):67-72

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Can Spelling Checkers Help the Novice Writer?     

Renu Gupta 《British journal of educational technology : journal of the Council for Educational Technology》1998,29(3):255-266

This paper argues that one type of text analyser—the spelling checker—can help non-proficient writers. 16 students in a Singapore classroom wrote compositions by hand for one month; the following month they composed their compositions directly on the computer. Observations of students' composing behaviours and a comparison of the lexis used in two students' hand-written and computer essays show that students use the spelling checker for two functions: (a) word-correction, in which they locate and correct some of their spelling errors, and (b) word-generation, in which they use the spelling checker to generate words that are in their receptive but not their productive vocabularies. The spelling checker benefits those students whose initial writing ability is poor and whose writing is blocked by an emphasis on the mechanical aspects of writing.  相似文献