Implementation of tetra-poly(ethylene glycol) hydrogel with high mechanical strength into microfluidic device technology     

Hiroaki Takehara  Akira Nagaoka  Jun Noguchi  Takanori Akagi  Takamasa Sakai  Ung-il Chung  Haruo Kasai  Takanori Ichiki 《Biomicrofluidics》2013,7(5)

Hydrogels have several excellent characteristics suitable for biomedical use such as softness, biological inertness and solute permeability. Hence, integrating hydrogels into microfluidic devices is a promising approach for providing additional functions such as biocompatibility and porosity, to microfluidic devices. However, the poor mechanical strength of hydrogels has severely limited device design and fabrication. A tetra-poly(ethylene glycol) (tetra-PEG) hydrogel synthesized recently has high mechanical strength and is expected to overcome such a limitation. In this research, we have comprehensively studied the implementation of tetra-PEG gel into microfluidic device technology. First, the fabrication of tetra-PEG gel/PDMS hybrid microchannels was established by developing a simple and robust bonding technique. Second, some fundamental features of tetra-PEG gel/PDMS hybrid microchannels, particularly fluid flow and mass transfer, were studied. Finally, to demonstrate the unique application of tetra-PEG-gel-integrated microfluidic devices, the generation of patterned chemical modulation with the maximum concentration gradient: 10% per 20 μm in a hydrogel was performed. The techniques developed in this study are expected to provide fundamental and beneficial methods of developing various microfluidic devices for life science and biomedical applications.  相似文献   

Contribution of discourse and morphosyntax skills to reading comprehension in Chinese dyslexic and typically developing children     

Pakey Pui-man Chik  Connie Suk-han Ho  Pui-sze Yeung  Yau-kai Wong  David Wai-ock Chan  Kevin Kien-hoa Chung  Lap-yan Lo 《Annals of dyslexia》2012,62(1):1-18

This study aimed at identifying important skills for reading comprehension in Chinese dyslexic children and their typically developing counterparts matched on age (CA controls) or reading level (RL controls). The children were assessed on Chinese reading comprehension, cognitive, and reading-related skills. Results showed that the dyslexic children performed significantly less well than the CA controls but similarly to RL controls in most measures. Results of multiple regression analyses showed that word-level reading-related skills like oral vocabulary and word semantics were found to be strong predictors of reading comprehension among typically developing junior graders and dyslexic readers of senior grades, whereas morphosyntax, a text-level skill, was most predictive for typically developing senior graders. It was concluded that discourse and morphosyntax skills are particularly important for reading comprehension in the non-inflectional and topic-prominent Chinese system.  相似文献   

High School Students’ Informal Reasoning Regarding a Socio‐scientific Issue,with Relation to Scientific Epistemological Beliefs and Cognitive Structures     

Ying‐Tien Wu  Chin‐Chung Tsai 《International Journal of Science Education》2013,35(3):371-400

This study investigated the relationship among 68 high school students’ scientific epistemological beliefs (SEBs), cognitive structures regarding nuclear power usage, and their informal reasoning regarding this issue. Moreover, the ability of students’ SEBs as well as their cognitive structures for predicting their informal reasoning regarding this issue was also examined. The participants’ SEBs were assessed with a quantitative instrument; their cognitive structures were assessed through tape‐recorded interviews and were further analyzed with the ‘flow map method’; their reasoning regarding nuclear power usage was assessed with an open‐ended questionnaire; and, then, their responses were analyzed both qualitatively and quantitatively. It was revealed that students’ beliefs about the justification of scientific knowledge (an aspect of the beliefs on the nature of knowing science) were significantly correlated with their reasoning quality; the extent and the richness of students’ cognitive structures as well as their usage of the information processing mode, ‘comparing,’ were positively correlated with their reasoning quality. A series of regression analyses further confirmed that students’ use of the information processing mode, ‘comparing,’ was the most significant factor for predicting reasoning quality, while their beliefs regarding the justification of scientific knowledge was the other important predictor.  相似文献   

Student Decision-Making about a Globally Familiar Socioscientific Issue: The value of sharing and comparing views with international counterparts     

Marcus Grace  Yeung Chung Lee  Roman Asshoff  Anita Wallin 《International Journal of Science Education》2013,35(11):1855-1874

This paper focuses on the views of 16–17-year-old science students from England, Germany, Hong Kong and Sweden on whale hunting, and their perceptions of the views of their international counterparts. The students were all provided with the same decision-making task, discussed the issue in small groups and then presented their views on video, which were shared with their counterparts. The findings show that the decision-making task served to deepen and modify students' views across all nationalities, and the students generally valued and learned from the sharing of views with students of the same age from around the world. However, an important discovery was that the German students' opinions often ran counter to those from the other 3 locations, and the paper cautions against making broad-sweeping generalisations about students' views on socioscientific issues.  相似文献   

The Impact of Bombing Attacks on Civilians in Iraq     

Fuaad Mohammed Freh  Rudi Dallos  Man Cheung Chung 《International journal for the advancement of counseling》2013,35(4):273-285

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Korean temporary migrant mothers' conceptualization of parent involvement in the United States     

Hoewook Chung 《Asia Pacific Journal of Education》2013,33(4):461-475

The purpose of this study is to gain insight into how Korean temporary migrant mothers conceptualize the nature of parent involvement in the USA. The participants in this study consisted of Korean mothers who were educated in Korea, migrated temporarily to the USA for educational purposes, and sent their children to American schools. Using the perspective of figured worlds, this study examines how these Korean mothers enact their figured worlds of parent involvement. Year-long qualitative case studies were conducted with six Korean mothers in Maxwell, a city in the Midwestern USA. The data included individual interviews, a focus group interview, observations, and document collection. The study found that the mothers engaged in a process of “figuring out” what it meant to be parents as they interacted with schools. In this process, they improvised, creating strategies to negotiate their social positions so that they can influence the school life of their children. The Korean mothers were authors of their worlds, and their engagement was a story of improvisations.  相似文献   

Early Neglect Is Associated With Alterations in White Matter Integrity and Cognitive Functioning     

Jamie L. Hanson  Nagesh Adluru  Moo K. Chung  Andrew L. Alexander  Richard J. Davidson  Seth D. Pollak 《Child development》2013,84(5):1566-1578

Cognitive deficits have been reported in children who experienced early neglect, especially children raised in institutionalized settings. Previous research suggests that early neglect may differentially affect the directional organization of white matter in the prefrontal cortex (PFC). This may be one mechanism to explain cognitive deficits associated with neglect. To test this idea, properties of white matter and neurocognitive performance were assessed in children who suffered early neglect and those raised in typical environments (n = 63, M_age = 11.75 years). As predicted, prefrontal white matter microstructure was affected, consistent with more diffuse organization, in children that suffered early neglect and this was related to neurocognitive deficits. Such findings underscore how early adversity may affect the PFC and explain cognitive deficits associated with neglect.  相似文献   

An analysis model of creating a core journal collection for academic libraries     

Hye-Kyung Chung   《Library Collections, Acquisitions, and Technical Services》2009,33(1):17-24

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A case example of assessment and evaluation: Building capability in a corporate university     

Shawn Overcast  Therese Schmidt  Kimfong Lei  Carrie Rodgers  Nigel A. Chung 《Performance Improvement》2009,48(6):5-15

One corporate university makes measurement a priority by dedicating resources and assigning responsibilities to a centralized analytics function: the assessment, measurement, and evaluation team. As more measurement became a focus for learning and business leaders alike, the more the team became motivated to take a critical look at how it was approaching assessment, measurement, and evaluation activities and how it could leverage its capabilities, technology, and processes to have a greater reach across the organization.  相似文献   

Book reviews     

Reinhard Bendix  G. de Landsheere  Hermann Röhrs  Christian Kluth  Menachem Gerson  Christine Laconte  Elliot W. Eisner  Ludwig Liegle  Françoise Bacher  Cesar Birzea  A. Harry Passow  G. F. Peaker  Jerry Norman Haar  Paul E. Peterson  Nigel Grant  Bom Mo Chung  Klaus Schleicher  Philip G. Altbach  T. Neville Postlethwaite  Tessa Blackstone 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》1973,19(2):262-298

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