Editorial     

Gareth Parry 《Higher Education Quarterly》2001,55(2):105-108

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Exercise and inflammation in coronary artery disease: A systematic review and meta-analysis of randomised trials     

Gareth Thompson  Gareth W. Davison  Jacqui Crawford 《Journal of sports sciences》2020,38(7):814-826

ABSTRACT

Current evidence suggests that chronic inflammation contributes to the development of coronary artery disease (CAD). Interestingly, exercise may constitute a method of reducing inflammation in this patient population. As such, this systematic review and meta-analysis examined the evidence generated by randomised studies that investigated the effect of exercise on inflammatory biomarkers in CAD. Literature was sought from various sources. Outcomes were pooled in a random-effects model to calculate standardised mean differences (SMD) with 95% confidence intervals (CI). Twenty-five studies were reviewed; post-intervention C-reactive protein (SMD: ?0.55 (95% CI: ?0.93, ?0.16), P = 0.005), fibrinogen (SMD: ?0.52 (95% CI: ?0.74, ?0.29, P = <0.00001)), and von Willebrand factor (SMD: ?1.57 (95% CI: ?2.23, ?0.92), P = <0.00001) values were significantly lower in exercise groups compared to controls. In addition, qualitative analyses identified evidence that supports a beneficial effect of exercise on these acute-phase reactants. However, the impact of exercise on anti–inflammatory cytokines, adhesion molecules, and chemokines is equivocal, which may be attributed to a paucity of research. Nevertheless, the findings of this review suggest that exercise induces an anti–inflammatory effect in CAD patients. Although, the quality of evidence needs to be improved by further randomised studies with high methodological qualities and large sample sizes.  相似文献   

Thiolene-based microfluidic flow cells for surface plasmon resonance imaging     

Sheppard G  Oseki T  Baba A  Patton D  Kaneko F  Mao L  Locklin J 《Biomicrofluidics》2011,5(2):26501

Thiolene-based microfluidic devices have been coupled with surface plasmon resonance imaging (SPRI) to provide an integrated platform to study interfacial interactions in both aqueous and organic solutions. In this work, we develop a photolithographic method that interfaces commercially available thiolene resin to gold and glass substrates to generate microfluidic channels with excellent adhesion that leave the underlying sensor surface free from contamination and readily available for surface modification through self-assembly. These devices can sustain high flow rates and have excellent solvent compatibility even with several organic solvents. To demonstrate the versatility of these devices, we have conducted nanomolar detection of streptavidin-biotin interactions using in situ SPRI.  相似文献   

Editorial     

Gareth Parry 《Higher Education Quarterly》2002,56(2):123-125

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Higher Education in Wales: The (Re-)emergence of a National System?     

Gareth Rees  & David Istance 《Higher Education Quarterly》1997,51(1):49-67

This paper explores historical patterns of change in participation in higher education in Wales, using as an organising framework Halsey's (1992) distinction between higher education as an administrative and as a social system. The nineteenth-century development of Welsh higher education was both part of a distinctive national political project and reflected the specificities of wider Welsh society. Expansion through the early and middle decades of the present century eroded this distinctiveness, as both the governance of Welsh higher education and patterns of student recruitment and participation became increasingly integrated into an 'England and Wales' system. The more recent expansion of higher education institutions in Wales, as well as the participation of Welsh students in higher education overall, has further accentuated this social integration into an 'England and Wales' system. Currently, Wales exhibits a pattern of participation which is unique amongst the home countries, whereby the Welsh higher education institutions serve very substantial numbers of students from England (and to a much lesser extent elsewhere), whilst a large proportion of Welsh students register at institutions in England. This indicates that there is now a significant disjuncture between an increasingly distinct pattern of governance of Welsh higher education and a pattern of participation which is massively integrated in the 'England and Wales' system.  相似文献   

Book reviews     

D. Bruce Johnstone  Samuel E. Kellams  J. Burke  L. J. Barker  Gareth Williams 《Higher Education》1981,10(5):605-612

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Special issue on total quality management in higher education     

Dr. Gareth Williams  Dr. Cari Loder 《Higher Education》1993,25(3):227-227

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Unpacking Participatory Research in Education   总被引：1，自引：0，他引：1  

Helen P. Hansen  Jennaya Ramstead  Stephen Richer  Susan Smith  Mary Stratton 《Interchange》2001,32(3):295-322

The authors of this paper are members of Ottawa Participatory Researchers in Education (OPRE) a group of teachers, university academics, and students attempting to develop research initiatives using democratic and collaborative research approaches. Building on the experiences of the group, the paper examines and problematizes three elements typically ascribed to non-traditional research approaches: a social action focus, a transformative objective, and a participatory process. Particular emphasis is placed on the questions of who participates, in what ways, and under what conditions. As a result of OPRE's experience and self reflection, seven traps of "pseudo-democracy" are identified and illustrated as potential problems in research purporting to embody equal collaboration between university based academics and community members, such as teachers and students. It is argued that in order to further a democratic research process, equality of opportunity to participate cannot be assumed at any stage of the research process. Attention is paid to the following stages: setting the research agenda, the research epistemology, chronology of the project, representativeness of project participants, funding processes, knowledge cultures, and dissemination choices. Conclusions call for raising awareness of the possibility of teachers and students collaborating to identify research issues of mutual concern and developing a controlling role in research where academics are included as consultants and equals, but not as the possessors of superior and controlling research expertise.  相似文献   

Considerations of force plate transitions on centre of pressure calculation for maximal velocity sprint running     

Timothy A. Exell  Marianne J.R. Gittoes  Gareth Irwin  David G. Kerwin 《Sports biomechanics / International Society of Biomechanics in Sports》2013,12(4):532-541

The aims of this study were to evaluate the accuracy of centre of pressure (COP) data obtained during transition of load across the boundary between two force plates, and secondly to examine the effect of such COP data on joint kinetics during sprint running performances. COP data were collected from two piezoelectric force plates as a trolley wheel was rolled across the boundary between the plates. Position data for the trolley were collected using an opto-electronic motion analysis system for comparison with COP data. Mean COP errors during transition across the plate boundary were 0.003 ± 0.002 m relative to a control point. Kinematic and kinetic data were also collected from eight athletes during sprint running trials to demonstrate the sensitivity of the inverse dynamics analysis to COP error for the ground contact phase of the dynamic movement trials. Kinetic sensitivity to the COP error was assessed during the entire stance phase for the ankle, knee, and hip joints and was less than 5% and 3% for joint moment and power data, respectively. Based on the small COP error during transition across plate boundaries, it is recommended that foot contacts overlapping two force plates may be included in inverse dynamics analyses.  相似文献   

大熊猫——中国的国宝     

Gareth Davey 《海外英语》2006,(5):44-45

本文由一位外籍老师撰写,喜爱大熊猫的他通过对我国大熊猫现状的调查,呼吁大家一起珍爱我们的国宝。  相似文献