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To elucidate a higher rate of premature cardiovascular disease (CVD) in Asian Indian descendants (Roma) in Slovakia, we investigated frequency distribution, correlates and relationship of lipoprotein(a) [Lp(a)] to family CVD risk factors in Roma children and their Caucasian neighbors. The study sample consisted of 607 healthy children aged 7–18 years (55% Roma, 48% male) as part of the biracial (Roma–Caucasian) Slovak Lipid Community Study. Overall, frequency distribution data of Lp(a) were highly skewed to low concentrations, with markedly higher Lp(a) levels in Roma than in Caucasian children (median and range, mg/dL: 14.5; 0–159.2 vs 6.2; 0–112.3, P < 0.001), regardless of age and gender. Lp(a) was positively correlated with apo B (0.159, P = 0.004) in Roma, and LDL cholesterol (0.170, P = 0.005) in Caucasian children. In addition, daily income of the family was negatively related with Lp(a) in Roma (−0.134, P = 0.036) while positively in Caucasians (0.136, P = 0.047). For both race groups, no significant association was found between Lp(a) and age, body mass index, mean arterial pressure, smoking, and physical activity. Also, no significant relationships were examined between serum Lp(a) levels >30 mg/dL in children and family CVD risk factors, except for diabetes mellitus in parents of Caucasian origin (OR 4.46; 95%CI: 1.23–16.20). In a multivariate analysis, daily income, LDL cholesterol or apo B explained ~7% of the variance of Lp(a). This study suggests a significantly higher serum Lp(a) levels in Roma than in Caucasian children and a small effect, in general, of relevant CVD risk factors on the variation of Lp(a) levels in childhood.  相似文献   
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Background: To minimise retrieval bias, manual literature searches are a key part of the search process of any systematic review. Considering the need to have accurate information, valid results of the manual literature search are essential to ensure scientific standards; likewise efficient approaches that minimise the amount of personnel time required to conduct a manual literature search are of great interest. Objective: The objective of this project was to determine the validity and efficiency of a new manual search method that utilises the scopus ? database. Methods: We used the traditional manual search approach as the gold standard to determine the validity and efficiency of the proposed scopus method. Outcome measures included completeness of article detection and personnel time involved. Using both methods independently, we compared the results based on accuracy of the results, validity and time spent conducting the search, efficiency. Results: Regarding accuracy, the scopus method identified the same studies as the traditional approach indicating its validity. In terms of efficiency, using scopus led to a time saving of 62.5% compared with the traditional approach (3 h versus 8 h). Conclusions: The scopus method can significantly improve the efficiency of manual searches and thus of systematic reviews.  相似文献   
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ABSTRACT

The paper examines social learning processes among organic farmers and explores the application of the Community of Practice (CoP) model in this context. The analysis employed utilises an approach based on the CoP model, and considers how, or whether, this approach may be useful to understand social learning among farmers. The CoP model is applied to case studies of social learning fora among organic farmers. The case studies are compiled from in-depth semi-structured interviews and participant observation with farmers and other actors, and the data are analysed with reference to three dimensions of the CoP model, namely mutual engagement, joint enterprise and shared repertoires. Farmers associate and engage in social learning more readily with peers determined by similar attitudes to farm business, farming styles and understanding of what organic agriculture entails. Such associations support the hypothesis that CoPs are self-organising structures that generate their knowledge in sympathy with community definition and identity. A CoP framework applied within relatively unstructured and dispersed communities, such as described in this paper, emphasises the fluid nature of CoPs, and their essentially self-organising nature. Extension approaches may be facilitated by regarding farmers as de-facto members of CoPs and by understanding how CoPs may form and develop. The CoP model is applied as a heuristic to examine social learning processes in organic farming.  相似文献   
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The rise in the prevalence of autism creates a need for a reliable and valid measure of attitudes towards autism. The current study describes the development of a brief 16‐ item measure of Societal Attitudes towards Autism (SATA) that exhibits sound psychometric properties and has a demonstrated ability to discriminate between expert and general college student samples. The final SATA was the result of pilot work on 75 items and exploratory and confirmatory factor analyses on a 45‐item version with 475 undergraduates. Knowledge and personal distance subscales yielded inconsistent reliability and validity outcomes. The SATA showed strong content and construct validity as evidenced by known groups discrimination, and predicted associations with an attitude towards disability measure, an autism preference item, and a measure of implicit attitudes towards disabilities.  相似文献   
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本文探讨了大学教育的经济学与公共物品的功利主义概念.笔者认为,现代大学的发展与演变是与物品这一概念的变化相伴随的.早期的自由主义经济学理论(代表人物如穆勒)认为,一种物品能够被供给,要么是因为它作为一个整体对社区有益,要么是因为它不能或者不应该通过私人的方式供给,比如国防.正如国家和社会在规则制定与福利供给方面变得越来越复杂,物品的定义也日益复杂.政策的合理性往往是通过它有助于公共财富的积累而得到证明的,具体来讲,政策应该要么满足社会受众的某种具体利益(这种福利是需要政府提供的,如学生的受教育经费),要么增进社会作为一个整体的利益(比如受教育人口的增长).这与现代大学的成长和进步是并行不悖且相互砥砺的.新自由主义的观点是对以上观点的一种挑战,它认为私人的投资与供给所产生的回报要远高于公共的投资与供给,而且从道义上来讲,个人与社会对于供给何种物品应该具有选择权;同时,由经济效能与个人选择所带来的混合的社会利益可以获致更多的集体公共物品.然而,这种观点没有考虑到规范的议题(如公平与社会正义)的影响.因此,本文旨在思考上述几重张力对于以下问题的影响,这些问题包括现代大学与公共物品的当代意涵之间的联系,以及大学占统治地位的经济功能能否与其在知识和文化方面的使命相协调.  相似文献   
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This Monte Carlo study examines the performance of fit indices commonly used by applied researchers interested in finite mixture modeling for the purposes of classification. Conditions for the simulation study were selected to reflect conditions found in applied educational and psychological research. The factors included in the investigation were metric level of indicators, sample size, and class prevalence. All models contained a combination of categorical and continuous indicators. All categorical indicators were dichotomous, and continuous indicators were normally distributed. The fit indices examined were Akaike’s information criterion, Bayesian information criterion (BIC), sample size-adjusted Bayesian information criterion (SSBIC), integrated classification likelihood criterion with Bayesian-type approximation, and Lo–Mendell–Rubin likelihood ratio test. Overall, SSBIC tended to identify the correct solution with higher frequency than other indices. BIC tended to identify the correct solution with higher frequency than the other indices in models with more continuous than categorical indicators, or when rare classes were absent.  相似文献   
59.
Whether and to what extent kindergarten children's executive functions (EF) constitute promising targets of early intervention is currently unclear. This study examined whether kindergarten children's EF predicted their second-grade academic achievement and behavior. This was done using (a) a longitudinal and nationally representative sample (N = 8,920, Mage = 97.6 months), (b) multiple measures of EF, academic achievement, and behavior, and (c) extensive statistical control including for domain-specific and domain-general lagged dependent variables. All three measures of EF—working memory, cognitive flexibility, and inhibitory control—positively and significantly predicted reading, mathematics, and science achievement. In addition, inhibitory control negatively predicted both externalizing and internalizing problem behaviors. Children's EF constitute promising targets of experimentally evaluated interventions for increasing academic and behavioral functioning.  相似文献   
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Students with LD who struggle with reading comprehension can benefit from instruction on how to read strategically. One strategy that has been demonstrated to increase reading comprehension is self‐questioning. In this study, two fifth graders with LD were taught to self‐generate questions using a prompt fading procedure. The participants were provided with expository reading passages with embedded questions. As each participant demonstrated proficiency with answering the embedded questions correctly, the embedded questions were systematically faded and replaced with a prompt for the students to generate their own questions. A multiple baseline across participants design demonstrated that the self‐questioning intervention resulted in improvements in reading comprehension for both students. Additionally, the students demonstrated evidence of maintenance and generalization of reading comprehension outcomes.  相似文献   
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