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Many countries spend sizeable sums of public money on R&D grants to alleviate debt and equity gaps for small firms’ innovation projects. In making such awards, knowledgeable government officials may certify firms to private financiers. Using a unique Belgian dataset of 1107 approved requests and a control group of denied requests for a specific type of R&D grant, we examine the impact of subsidies on small firms’ access to external equity, short term and long term debt financing. We find that obtaining an R&D subsidy provides a positive signal about SME quality and results in better access to long-term debt. 相似文献
73.
Tauler P Ferrer MD Romaguera D Sureda A Aguilo A Tur J Pons A 《Journal of sports sciences》2008,26(12):1303-1311
In this study, we examined oxidative stress after a swimming session, the responses of the antioxidant defences, and the influence of gender on these responses. Fifteen boys and eight girls participated voluntarily in the study. Plasma concentrations of 17-beta-estradiol, vitamin E, retinol, carotenes, ascorbate, malondialdehyde, and the carbonyl index were determined. Creatine kinase, gamma glutamyl transpeptidase, and lactate dehydrogenase activities, as well as glucose, urea, urate, cholesterol, and triglycerides, were determined in serum. Plasma concentrations of 17-beta-estradiol were higher in girls than in boys. Exercise increased plasma ascorbate both in boys and in girls. Malondialdehyde increased in boys but was maintained in girls after exercise. Creatine kinase values corrected for lean body mass were similar in boys and girls at baseline, but the post-exercise values in boys were higher than in girls. A positive correlation was observed in boys, but not in girls, between plasma malondialdehyde and creatine kinase corrected concentrations. Furthermore, a negative correlation was observed between the increase in circulating neutrophils and in creatine kinase activity in girls but not in boys. In conclusion, a swimming session induced higher muscular and oxidative damage in boys than in girls. 相似文献
74.
Miguel Asencio 《图书馆管理杂志》2017,57(7):818-825
This article will provide a brief overview of the successes of the Digital Library of the Caribbean, an open access, multi-institutional, multilingual, inclusive, international digital library. It will discuss factors that support the sustainability of robust technical infrastructures, collaborative partnerships, shared governance, and shared interests in advancing Caribbean scholarly research. Partner relationships and shared governance are at the heart of the creativity and solutions which continue to grow the largest Caribbean content digital library in the world. 相似文献
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76.
Carlos Rodriguez‐Solano Salvador Sánchez‐Alonso Miguel‐Angel Sicilia 《British journal of educational technology : journal of the Council for Educational Technology》2015,46(6):1223-1235
Open textbook initiatives have appeared as an alternative to traditional publishing. These initiatives for the production of alternatively copyrighted educational resources provide a way of sharing materials through the Web. While the open model of peer‐produced materials enables the global reuse of textbooks, the combination of fragments to produce new textbooks tailored to particular needs is not easy. The heterogeneity of topics and target audiences, as well as the cultural and institutional differences of educational systems across the globe, raises the need for new compositional features, fostering—at the same time—the reuse of the newly produced combinations. This paper reviews the current models of reuse and sharing, and presents a quantitative analysis of the Connexions repository which provides evidence about the culture of reuse in open textbook initiatives. 相似文献
77.
Miguel Gómez 《学校用计算机》2015,32(3-4):278-299
The technological pedagogical content knowledge (TPACK) conceptual framework, since its introduction in 2006, has provided researchers and teacher educators a theoretical means by which to understand the knowledge required to teach effectively with technology. However, a clear picture of what TPACK looks like in practice is still in its infancy. Using a case-study approach, this research examines the teaching practices of an eighth-grade social studies teacher, specifically how the teacher operationalizes TPACK within his classroom. Four examples of TPACK practices are given along with the teacher's rationale for his technology use. Two themes emerged: the transformation of technology into something that just happens in the classroom and the teacher's use of technology to shape instruction. Implications from this case study are then discussed, including the process and timing of combining the different knowledge components of TPACK and the need to better capture the role of students in the TPACK model. 相似文献
78.
Tiago Oliveira Miguel Faria Manoj Abraham Thomas Aleš Popovič 《International Journal of Information Management》2014
Mobile banking (mBanking) enables customers to carry out their banking tasks via mobile devices. We advance the extant body of knowledge about mBanking adoption by proposing a model for understanding the importance and relationship between the user perception of mBanking, initial trust in mBanking services, and the fit between the technology and mBanking task characteristics. We synergistically combine the strengths of three IS theories – task technology fit (TTF) model, unified theory of acceptance and usage of technology (UTAUT), and initial trust model (ITM). The model was tested in a study conducted in Portugal, one of the European Union (EU) countries with the highest mobile phone adoption. Based on the sample of 194 individuals we applied partial least squares (PLS) to test the conceptual model propose. The path significance levels were estimated using the bootstrapping method (500 resamples). The study found that facilitating conditions and behavioral intentions directly influence mBanking adoption. Initial trust, performance expectancy, technology characteristics, and task technology fit have total effect on behavioral intention. The paper offers valuable insights to decision-makers involved in the implementation and deployment of mBanking services. For researchers, the paper highlights the usefulness of integrating TTF, UTAUT and ITM in the development of a decision support framework to study the adoption of new technologies. 相似文献
79.
Miguel A. Acosta Xiao Jiang Pin-Kang Huang Kyle B. Cutler Christine S. Grant Glenn M. Walker Michael P. Gamcsik 《Biomicrofluidics》2014,8(5)
Metastatic cancer cells must traverse a microenvironment ranging from extremely hypoxic, within the tumor, to highly oxygenated, within the host''s vasculature. Tumor hypoxia can be further characterized by regions of both chronic and intermittent hypoxia. We present the design and characterization of a microfluidic device that can simultaneously mimic the oxygenation conditions observed within the tumor and model the cell migration and intravasation processes. This device can generate spatial oxygen gradients of chronic hypoxia and produce dynamically changing hypoxic microenvironments in long-term culture of cancer cells. 相似文献
80.
Bill?McKelveyEmail author Maria Paz?Salmador Patricio?Morcillo José Miguel?Rodríguez-Antón 《知识管理研究与实践》2013,11(2):142-161
The paper begins with research studying the concept and nature of Intellectual Capital (IC), as well as how close IC firms are to the stochastic frontier. Then basic concepts of complexity theory – such as agents, self-organized criticality (SOC), connectivities, fractals, and power laws (PLs) – are used to distinguish between two kinds of IC firms’ success: traditional SOC applications to how firms maintain their position in a changing industry vs. how an IC firm (such as Apple) creates a new stochastic frontier. The research sets up PLs as indicators of whether or not firms and industries are SOC-effective and includes propositions about: (1) How IC firms benefit from complexity dynamics and SOC; (2) How PL distributions are indicators of efficacious SOC and adaptivity; and (3) Why IC attributes serve to create more transient dynamics pertaining to the stochastic frontier and the rest of the industry's rank/frequency distribution. 相似文献