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11.
Viral infection with hepatitis C virus (HCV) has a high propensity in becoming chronic and it is the major cause of hepatocellular carcinoma (HCC) worldwide. This review was basically established to illustrate the putative role of the P53 gene Arg72Pro polymorphism on various cancer models and viral infections, focusing on HCV and HCC incidences. Authors studied the 72 G/C single base substitution of P53 gene at codon 72 using various polymorphic techniques. Intriguingly, authors investigated that the P53 codon 72 plays a crucial role as risk factor in several cancer models. Others found that there is no association between codon 72 genotypes and HCV disease severity or liver cancer. Moreover, the lack of a significant relationship between this polymorphism and risk of HCC shows that it does not predispose towards hepatocarcinogenesis and the frequent loss of the proline allele in HCV-associated carcinogenesis of the liver plays some critical role in hepatocarcinogenesis. Amazingly, there is a significant correlation between male homozygotes for P53 72Pro with HCV type 1b infection. However, there was no significant difference between the P53 polymorphism and HCV genotypes 2a and 2b. It was concluded that the P53 gene polymorphism at codon 72 has been investigated as potential risk factor in several cancer models and HCV infections.  相似文献   
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We consider the leader–follower consensus problem for a multi-agent system where information is exchanged only on a non-uniform discrete stochastic time domain. For a second-order multi-agent system subject to intermittent information exchange, we model the tracking error dynamics as a μ?varying linear system on a discrete stochastic time scale, where μ is the graininess operator. Based on a Lyapunov operator and a positive perturbation operator on the space of symmetric matrices, we derive necessary and sufficient conditions to design a decentralized consensus protocol. This protocol allows us to cast the mean-square exponential consensus problem within the framework of dynamic equations on stochastic time scales. We establish some theoretical results which allow for the computation of the control gain matrix which guarantees the mean-square exponential stability with a given decay rate for the error dynamics. To show the effectiveness of the theoretical results, some simulation and experimental results on multi-robot systems have been performed.  相似文献   
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In this article, we study the finite-time stability (FTS) and finite time stabilization problems for a class of switched impulsive systems evolving on an arbitrary time domain. This problem is formulated using time scale theory where the time domain can be continuous, discrete, union of disjoint intervals with variable gaps and variable lengths or any combination of these. Using common Lyapunov-quadratic and Lyapunov-like functions, we establish sufficient conditions to ensure the FTS results. Further, to solve the stabilization problem, we design state feedback controllers. We have illustrated the effectiveness of the obtained analytical results though numerical examples.  相似文献   
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Studies (for example, Dellaportas in Making a difference with a discrete course on accounting ethics. J Bus Ethics 65(4):391–404, 2006; Saat in An investigation of the effects of a moral education program on the ethical development of Malaysian future accountants, 2010) on final year accounting students show that industrial training has a positive impact on the ethical development in a way that students improved in their ethical judgement after attending a 6-month training. Thus, this research aims to evaluate the influence of industrial training in the development of ethical awareness among final year students from a Malaysian public university. These students were from multiple academic backgrounds—engineering, science and social science. A pre and post study was adopted in order to achieve the objectives. A set of survey was distributed to students before and after they have attended industrial training. In assessing students’ ethical awareness, 15 business-related and workplace ethical situations were given and students had to rate their acceptance on these situations from not acceptable (1) to most acceptable (7). From the findings, it can be observed that although the level of ethical awareness among students is fairly good, industrial training has minimal impact in improving or developing students’ ethical awareness. The impact is such because students who undergone industrial training may have observed certain behaviour that they thought are acceptable in a workplace; this may have changed the way students perceived their acceptance on the situations.  相似文献   
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Abstract

Purpose: The study investigated to what extent local farmers' organisations are spaces where farmers discuss, learn and innovate.

Design/methodology/approach: Two milk collection cooperatives in Morocco were studied. The study analysed the discussion networks, their impacts on farmers' knowledge and innovation, and the performance of collective action at cooperative level.

Findings: In both cooperatives, only two-thirds of the farmers regularly discussed dairy practices with other farmers. Most leaders of one cooperative were acknowledged to be experienced farmers and played key roles as advisors on dairy farming. Farmers' involvement in dialogue networks in this cooperative improved their capacity to innovate in dairy farming, even though their knowledge on some issues related to cattle, health and nutrition was not improved. In the other cooperative, experienced farmers did not share their knowledge and farmers' involvement in dialogue networks at cooperative level had no impact on their knowledge and practices. Dialogue networks and collective action were found to influence each other, since in the first cooperative, collective action was considered by members to be efficient, whereas in the second collective action was limited to milk collection.

Practical implications: The study enabled identification of stumbling blocks which need to be addressed to get local farmers’ organisations involved in farmer capacity-building.

Originality/value: While the importance of local discussion networks for knowledge creation and diffusion is widely acknowledged, taking such networks into account in farmers' capacity-building programmes in developing countries has been hindered by their informality. Combining the analysis of dialogue networks and collective action proved to be a productive way to assess the potentialities of working with farmers' organisations with the aim of establishing a connection with local discussion networks.  相似文献   
18.
Forty-six Streptomyces strains were isolated from paintings and stone surfaces from Tell Basta and Tanis tombs (80 km south-east Cairo, Egypt). Eight of these strains were selected to determine their sensitivity against 13 antibiotics. In general, high levels of resistance could be observed. Gentamycin, spiramycin and doxycycline were the most effective antibiotics against the majority of strains under study. Due to the observed antibiotic resistances, gamma irradiation was studied as a possible alternative to inhibit microbial growth. Isolated bacteria were exposed to different doses of gamma irradiation (5, 10, 15, 20 and 25 kGy). The growth of all Streptomyces isolates except S. canarius was completely inhibited at 25 kGy. The applied doses of gamma irradiation did not cause any observable alterations or colour changes to pigments and binding media (arabic gum, animal glue and egg-yolk) used in the paintings.  相似文献   
19.
This article will explore collaborations between the University Libraries and the campus community in implementing diversity and inclusion initiatives on campus through participation in the National Coalition Building Institute (NCBI). The article will take an in-depth look at the prejudice reduction and discrimination trainings conducted in the FSU Libraries, and how the trainings contributed to implementing the Libraries' strategic initiative for diversity and inclusion. These partnerships between the Libraries and the campus community exemplify successful collaborations needed to achieve preeminent institutional goals like diversity and inclusion. FSU has been recognized for Higher Education Excellence in Diversity, and is a national Diversity Champion since 2014 (Insight into Diversity: online).  相似文献   
20.
Sound assessment and evaluation of higher education necessitates deep understanding of the detailed processes underlying student overall evaluation of course and Instructor. The present study employs both correlational analysis and step‐wise multiple regression in an effort to help us understand student decision behaviour and to build mathematical models representing the dynamics of student evaluative Judgement of course and instructor. The resulting models were very strong and were ctually used to improve the performance of the academic programmes in the Institute of Banking Studies In Kuwait.  相似文献   
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