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21.
Jamil Mikhail Yahaya Ahmad Nurulazam Md Zain Mageswary Karpudewan 《International Journal of Science and Mathematics Education》2015,13(2):467-491
This research investigates the effects of socioscientific instruction on pre-service teachers’ sense of efficacy in the teaching and learning of controversial family health issues. For this purpose, a total of 251 students from two teacher training colleges participated in the study and were randomly assigned as experimental and control groups. The experimental group was taught the contents of the controversial family health issues using socioscientific instruction approach and the control group was taught the same content using a more traditional approach. Quantitative data were obtained from both groups after responding to the ‘Teacher sense of Efficacy Scale’ as instrument used for data collection before and after the treatments. Analysis of covariance was used in data analysis of which the pre-treatment scores were used as covariates. Qualitative interviews were conducted with ten participants randomly selected from the experimental group before and after the treatment to deepen and elaborate the quantitative data. The quantitative and qualitative findings indicate that the integration of the socioscientific instruction have significantly affected the pre-service teachers’ sense of efficacy in favour of the experimental group that shows a more stronger sense of efficacy. It was concluded that the socioscientific instruction is significantly effective in changing the pre-service teachers’ weaker sense of efficacy to a stronger one in the controversial family health issues. 相似文献
22.
Eshrat Halim M. A. Hussain Kaiser Jamil Mala Rao 《Indian journal of clinical biochemistry : IJCB》2001,16(2):190-194
Effect of oral administration of 200 mg/Kg body weight of the aqueous extract ofOcimum sanctum (Tulsi) mixed with diet for eight weeks to diabetic (streptozotocin induced) rats was studied. There was significant reduction
in fasting blood glucose, serum lipid profile, lipid peroxidation products, (LPO) and improvement in glucose tolerance. The
aqueous extract also decreased LPO formation (thiobarbituric acid reactive substances TBARS) and increased antioxidant enzymes
superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione transferase (GT) and one antioxidant
reduced glutathione (GSH) in plasma and rat liver, lung, kidney and brain. The decrease in TBARS and increase in GSH, SOD,
CAT, GPX, and GT clearly shows the antioxidant property ofOcimum sanctum. 相似文献
23.
Mulberry longicorn beetle, Apriona germari, has been reported to produce two endo-β-l,4-glucanases or AgEGases (accession Nos. Q6SS52 and Q5XQD1). AgEGase sequence contains catalytic motif (amino acid residues 37～48), which is the characteristic of family Glycohydrolase 45 and is identified as the substrate binding site. The application of bioinformatics approaches includes sequence analysis, structural modeling and inhibitor docking to relate the structure and function of AgEGases.We have dissected the sequence and structure of AgEGase catalytic motif and compared it with crystal structure of Humicola insolens endoglucanases Ⅴ. The results show an involvement of sulfur containing amino acid residues in the active site of the enzyme. Cys residues and position of disulfide bonds are highly conserved between the two structures of endoglucanases of A.germari. Surface calculation of AgEGase structure in the absence of Cys residues reveals greater accessibility of the catalytic site to the substrate involving Asp42, a highly conserved residue. For the inhibition study, tannin-based structure was docked into the catalytic site of AgEGase using ArgusLab 4.0 and it resulted in a stable complex formation. It is suggested that the inhibition could occur through formation of a stable transition state analog-enzyme complex with the tannin-based inhibitor, as observed with other insect cellulases in our laboratory. 相似文献
24.
Bélanger Charles Longden Bernard Orozco Quijano E. Patricia Razmak Jamil 《Tertiary Education and Management》2019,25(2):161-180
Tertiary Education and Management - What relationships exist between Mexican students and their professors? This paper compares student expectations with their experiences. This comparison is done... 相似文献
25.
Haider Samee Zhen-xing Li Hong Lin Jamil Khalid Yong-chao Guo 《Journal of Zhejiang University. Science. B》2009,10(2):147-153
Ethanol extracts of brown seaweeds from Pakistan and China were isolated and compared for their antiallergenic activities.They included Sargassum tennerimum (ST) and Sargassum cervicorne (SC) from Pakistan,and Sargassum graminifolium turn (SG),Sargassum thunbergii (STH),and Laminariajaponica (LJ) from China.The ethanol extracts of these brown seaweeds were optimized at 85% (v/v) ethanol for the maximum yield of phlorotannin,an inhibitor against hyaluronidase.Total phlorotannins contained in the crude extracts were measured as 1.71% (SG),0.74% (STH),0.97% (LJ),3.30% (SC),and 5.06% (ST).The 50% inhibitory concentrations (IC50) of Pakistani SC and ST were 109.5 and 21 μg/ml,respectively,lower than those of Chinese SG,STH,and LJ (134,269,and 148 μg/ml,respectively).An antiallergic drug,disodium cromoglycate (DSCG),had an IC50=39 μg/ml,and a natural inhibitor of hyaluronidase,catechin,had an IC50=20 μg/ml.The IC50 of ST extract was found similar to that of catechin (21 vs 20 μg/ml) and lower than that of DSCG (21 vs 39 μg/ml).This suggests that ST is a potent inhibitor of hyaluronidase,indicating a promising future development of natural antiallergic medicines or functional foods. 相似文献
26.
Robert C. Pianta Margaret Burchinal Faiza M. Jamil Terri Sabol Kevin Grimm Bridget K. Hamre Jason Downer Jennifer LoCasale-Crouch Carollee Howes 《Early childhood research quarterly》2014
The present study examined the pattern of association(s) over time between (a) knowledge of and observational skills in identifying teacher–child interactions, and (b) observed behavior in the domain of instructional interaction for 405 preschool teachers enrolled in a professional development study. Teacher's knowledge/observational skills and observed instructional support behaviors with children were assessed in the fall and spring over a two-year period. During this time, the teachers were also randomized into a college course focused on interactions, then re-randomized into a coaching intervention, also focused on instructional interaction. Cross-lagged analyses suggest that prior observed behavior was the stronger predictor of change in both knowledge/observation skills and in later observed behavior, and that both the course and the coaching interventions contributed to improvements in teachers observed instructional support behavior. Mediational analyses of the course effects indicated longer-term impact on observed instructional behavior were through immediate impacts on those same behaviors, whereas long-term impacts on knowledge were through immediate impacts on both observed instructional behavior and knowledge. The results have implications for the design, delivery, and focus of professional development for early childhood educators. 相似文献
27.
This study evaluates a model for considering domain‐general and domain‐specific associations between teacher–child interactions and children's development, using a bifactor analytic strategy. Among a sample of 325 early childhood classrooms there was evidence for both general elements of teacher–child interaction (responsive teaching) and domain‐specific elements related to positive management and routines and cognitive facilitation. Among a diverse population of 4‐year‐old children (n = 1,407) responsive teaching was modestly associated with development across social and cognitive domains, whereas positive management and routines was modestly associated with increases in inhibitory control and cognitive facilitation was associated with gains in early language and literacy skills. The conceptual and methodological contributions and challenges of this approach are discussed. 相似文献
28.
This study was undertaken to isolate and characterize the protease activity of human eye lens sample of mature and hyper mature cataract. Samples were collected just after surgery of the cataract lens and were stored at -20°C. The total protein extract was isolated from 5 samples in each case (mature and hyper mature cataract) and clear supernatant obtained after centrifugation was used as an enzyme source. The optimum pH for the proteases of mature cataract was 7.5 while the proteases of hyper mature cataract were recorded for maximum activity at pH 5.5 and 7.5. The optimum temperature for both enzyme sources was 50 °C. Effect of different metal ions such as potassium, lead, silver, zinc and borate was studied. In each case protease activity was increased. Reducing agent e.g. β mercaptoethanol also caused an increase in activity indicating the involvement of sulfhydryl groups. Protease activity was also located on agar plates. 相似文献
29.
Mulberry longicorn beetle, Apriona germari, has been reported to produce two endo-β-1,4-glucanases or AgEGases (accession Nos. Q6SS52 and Q5XQD1). AgEGase sequence contains catalytic motif (amino acid residues 37~48), which is the characteristic of family Glycohydrolase 45 and is identified as the substrate binding site. The application of bioinformatics ap-proaches includes sequence analysis, structural modeling and inhibitor docking to relate the structure and function of AgEGases. We have dissected the sequence and structure of AgEGase catalytic motif and compared it with crystal structure of Humicola insolens endoglucanases V. The results show an involvement of sulfur containing amino acid residues in the active site of the enzyme. Cys residues and position of disulfide bonds are highly conserved between the two structures of endoglucanases of A. germari. Surface calculation of AgEGase structure in the absence of Cys residues reveals greater accessibility of the catalytic site to the substrate involving Asp42, a highly conserved residue. For the inhibition study, tannin-based structure was docked into the catalytic site of AgEGase using ArgusLab 4.0 and it resulted in a stable complex formation. It is suggested that the inhibition could occur through formation of a stable transition state analog-enzyme complex with the tannin-based inhibitor, as observed with other insect cellulases in our laboratory. 相似文献
30.
Umesh Sharma Sadia Shaukat Brett Furlonger 《Journal of Research in Special Educational Needs》2015,15(2):97-105
This study sought to determine the attitudes and teaching self‐efficacy of pre‐service teachers towards the inclusion of students with disabilities into regular classrooms. A questionnaire was administered to 194 pre‐service Pakistani teachers (male 73, female 121) enrolled in a 1‐year teacher education programme at a government university in Pakistan. Overall, male pre‐service teachers expressed more positive attitudes than their female counterparts regarding the inclusion of students with disabilities in regular classrooms. Surprisingly, those pre‐service teachers majoring in special education did not express more positive attitudes towards inclusion than their counterparts who were preparing to teach in mainstream schools. However, participants with training in special education, knowledge of disability legislation, teaching experience and personal experience with a disability reported higher levels of self‐efficacy towards teaching within inclusive settings. The findings of the study are discussed with possible implications for policy‐makers and teacher educators in Pakistan and other countries in the South Asian region. 相似文献