An efficient method of addressing ectopic beats: new insight into data preprocessing of heart rate variability analysis     

Wen F  He FT 《Journal of Zhejiang University. Science. B》2011,12(12):976-982

Heart rate variability (HRV) analysis is affected by ectopic beats. An efficient method was proposed to deal with the ectopic beats. The method was based on trend correlation of the heart timing signal. Predictor of R-R interval (RRI) value at ectopic beat time was constructed by the weight calculation and the slope estimation of preceding normal RRI. The type of ectopic beat was detected and replaced by the predictor of RRI. The performance of the simulated signal after ectopic correction was tested by the standard value using power spectrum density (PSD) estimation, whereas the results of clinical data with ectopic beats were compared with the adjacent ectopic-free data. The result showed the frequency indexes after ectopy corrected had less error than other methods with the test of simulated signal and clinical data. It indicated our method could improve the PSD estimation in HRV analysis. The method had advantages of high accuracy and real time properties to recover the sinus node modulation.  相似文献   

RRM1 gene expression in peripheral blood is predictive of shorter survival in Chinese patients with advanced non-small-cell lung cancer treated by gemcitabine and platinum     

Wang LR  Zhang GB  Chen J  Li J  Li MW  Xu N  Wang Y  Shen Tu JZ 《Journal of Zhejiang University. Science. B》2011,12(3):174-179

Objective  

To evaluate the predictive values of gene expressions of ribonucleotide reductase M1 (RRM1) and breast cancer susceptibility gene 1 (BRCA1) in peripheral blood from Chinese patients with non-small-cell lung cancer (NSCLC) treated with gemcitabine plus platinum.  相似文献   

Effect of epidermal growth factor on follicle-stimulating hormone-induced proliferation of granulosa cells from chicken prehierarchical follicles     

Lin JX  Jia YD  Zhang CQ 《Journal of Zhejiang University. Science. B》2011,12(11):875-883

The development of ovarian follicular cells is controlled by multiple circulating and local hormones and factors, including follicle-stimulating hormone (FSH) and epidermal growth factor (EGF). In this study, the stage-specific effect of EGF on FSH-induced proliferation of granulosa cells was evaluated in the ovarian follicles of egg-laying chickens. Results showed that EGF and its receptor (EGFR) mRNAs displayed a high expression in granulosa cells from the prehierarchical follicles, including the large white follicle (LWF) and small yellow follicle (SYF), and thereafter the expression decreased markedly to the stage of the largest preovulatory follicle. SYF represents a turning point of EGF/EGFR mRNA expression during follicle selection. Subsequently the granulosa cells from SYF were cultured to reveal the mediation of EGF in FSH action. Cell proliferation was remarkably increased by treatment with either EGF or FSH (0.1–100 ng/ml). This result was confirmed by elevated proliferating cell nuclear antigen (PCNA) expression and decreased cell apoptosis. Furthermore, EGF-induced cell proliferation was accompanied by increased mRNA expressions of EGFR, FSH receptor, and the cell cycle-regulating genes (cyclins D1 and E1, cyclin-dependent kinases 2 and 6) as well as decreased expression of luteinizing hormone receptor mRNA. However, the EGF or FSH-elicited effect was reversed by simultaneous treatment with an EGFR inhibitor AG1478. In conclusion, EGF and EGFR expressions manifested stage-specific changes during follicular development and EGF mediated FSH-induced cell proliferation and retarded cell differentiation in the prehierarchical follicles. These expressions thus stimulated follicular growth before selection in the egg-laying chicken.  相似文献   

Chaiqin Chengqi Decoction decreases IL-6 levels in patients with acute pancreatitis     

Wang L  Li Y  Ma Q  Liu Y  Rui YY  Xue P  Zhou ZG 《Journal of Zhejiang University. Science. B》2011,12(12):1034-1040

Objective  

In this paper, we investigated the effect of the traditional Chinese medicine Chaiqin Chengqi Decoction (CQCQD) on serum cytokines in acute pancreatitis (AP) patients.  相似文献   

依托度酸双层渗透泵控释片的制备     

常明  岳红坤  牟微  李超  刘树彬 《石家庄学院学报》2011,13(3):14-17,78

目的:制备依托度酸双层渗透泵控释片.方法:采用单因素法考察依托度酸渗透泵控释片体外释药行为的影响.结果:最佳片剂处方组成为:包衣膜增重为15%,聚氧乙烯(PEO)65%,CMS-Na 56 mg,HPMCK100M 45 mg,CP971NF 11.6 mg,PVPK30 22 mg,NaCl 32.5 mg.控释片批间重复性良好.结论:自制依托度酸双层渗透泵控释片工艺稳定,零级释药特征明显,24 h内释药完全.  相似文献   

英语词汇强度知识、深度知识与阅读关系探究     

邹俊飞 《衡阳师范学院学报》2011,32(5):134-138

英语词汇知识在英语阅读理解中所起的重要作用是毋庸置疑的,但是词汇知识的框架是复杂而多维的。测量了英语学习者的词汇强度知识及词汇深度知识,以揭示英语学习者英语词汇知识的全貌,并证实了英语词汇强度知识及深度知识在阅读中所起的不同作用。文章研究结果还表明,在词汇强度知识的四个样态中积极回忆样态对阅读有最强的预测力,而词汇深度知识中的词汇意义比搭配更能预测学习者的阅读能力。  相似文献   

罪名拟定的原则     

晋涛 《石家庄学院学报》2011,13(4):43-50

罪名拟定必须坚持概括原则、文本原则、协调原则、准确原则。概括原则是指罪名应当简约、精炼。文本原则是指拟定罪名应当尽量使用罪状中的表述词汇。协调原则要求罪名之间应当协调一致,相似、相近罪名应当呈现出规律性。准确原则是指罪名应当反映罪名的本质特征,不能出现罪名的外延大于或者小于罪状的情形,更不能产生歧义。新通过的《刑法修正案(八)》涉及的争议罪名,运用如上四个原则拟定,会得出恰当结论。  相似文献   

昆明裂腹鱼同工酶组织特异性研究     

胡思玉  陈永祥  赵海涛  王俊 《毕节学院学报》2011,29(4):100-105

采用不连续聚丙烯酰胺凝胶电泳法,对昆明裂腹鱼的眼球、心脏、肾脏、性腺、脾脏、肝胰脏、脑、鳃和肌肉等9种组织的4种同工酶进行了测定。结果表明:昆明裂腹鱼9种组织4种同工酶系统具有明显的组织特异性。  相似文献   

L-凸空间中的GLSKKM定理及其对不动点的应用   总被引：1，自引：1，他引：0  

李和睿  刘高文  文开庭 《毕节学院学报》2011,29(4):37-44

建立了L-凸空间中弱转移紧闭值集映射的GLSKKM定理,作为应用,获得了L-凸空间中的Ky Fan型匹配定理、Fan—Browder型重合定理和不动点定理。  相似文献   

用于吸附Cu(Ⅱ)材料的研究进展     

陈研研 《毕节学院学报》2011,29(4):95-99

二价铜离子作为水体中的主要污染物之一,一直是人们研究的焦点。通过对近几年来用于吸附二价铜离子的材料研究,并对影响其吸附的主要因素进行了阐述。结果表明,天然材料(如香蕉皮、谷壳等)在此领域具有价格低廉、操作简单的优势,极具开发前景。  相似文献