Detection of monoclonal protein by capillary zone electrophoresis can be challenged by iodinated contrast agent interference: a case report     

Clment Capaldo  Mourad Cheddad El Aouni  Damien Laurelli  Cyril Leven  Jean-Luc Carr 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(2)

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Contribution of the laboratory to a diagnosis process by sequential reflective testing: Paraprotein interference on a direct bilirubin assay     

Niyazi Samet Yilmaz  Bayram Sen  Ozlem Gulbahar 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(2)

Errors in laboratory medicine occur in the preanalytical, analytical, and postanalytical phases. The errors are mostly detected in the preanalytical period. However, analytical errors are still an important source of error, despite their frequency is reduced significantly in years thanks to developments in laboratories. In this case, an analytical error was noticed during the verification of a patient’s results. The direct bilirubin of a 66-year-old male patient admitted to the emergency department was higher than the total bilirubin. The patient’s symptoms were fatigue and dyspnoea. Albumin and haemoglobin (Hb) concentrations of the patient were significantly low. After considering the patient’s demographics and laboratory results, the laboratory specialist suspected a paraproteinemia interference. Total protein was performed as a reflective test. The albumin/globulin ratio was reversed. Thereafter, serum protein electrophoresis (SPEP) and immunofixation electrophoresis (IFE) were performed as another reflective tests, respectively. SPEP and IFE results were in favour of monoclonal gammopathy. The patient was directed to a haematologist, underwent a bone marrow biopsy, and the result was reported as Waldenstrom’s macroglobulinemia with plasma cell differentiation expressing IgM-Kappa. The patient went on a chemotherapy protocol, and his condition has been improved in subsequent months. Detection of analytical errors is of great importance, like in our case, and may be used as a tool to identify patients who have not yet been diagnosed. The laboratory specialist must dominate the entire process of each test in the laboratory, be aware of the limitations of tests, and turn these disadvantages into advantages when necessary.  相似文献   

中波同步广播单频覆盖网的干扰场分析     

应毓海 《合肥联合大学学报》2014,(1):59-62

通过介绍中波同步广播的发展历史,并对中波同步广播单频覆盖网形成的叙述,重点对中波同步广播单频覆盖网所形成相干区的要素进行分析。  相似文献   

光伏逆变器内部电磁干扰抑制电路研究     

李雅静  郑宏兴  刘新月 《天津职业技术师范学院学报》2014,(1):13-17

在光伏逆变系统中,内部电磁干扰是影响其工作稳定性和可靠性的重要因素,能否有效地控制内部电磁干扰决定着系统的成败.文章以一款3 kW离网光伏逆变器设计为例,分析了系统内部主要电磁干扰的分布,并提出了具体解决方案.  相似文献   

抗工频一阶有源高通滤波器的设计     

张翠明  刘凤梅  张会鹏 《石家庄职业技术学院学报》2014,26(6):50-52

为防止工频信号对模电实验中工作信号的干扰,通过对滤波器种类选择、滤波器电路参数确定的分析,设计了一种一阶有源高通滤波器.通过对有无滤波器两种电路实验效果的分析,验证了所设计滤波电路的有效性,提高了电子实验的准确性和抗干扰性.  相似文献   

基于Wilson模型改进的物流节点空间作用分析     

宋媛 《合肥教育学院学报》2014,(5):113-116

空间相互作用是物流空间学研究的主要内容之一。将物流空间相互作用定义为在经济、社会等因素的综合作用下,物流节点区域间通过物流设施和交通设施围绕着“物”的交流而产生的相互联系。在Wilson模型改进的基础上,以干扰因素为出发点,分两种情况进一步对节点间空间相互作用效果进行确定。  相似文献   

强杂波环境下网络病毒传播灰阶菌群免疫算法     

邹勇  黄丽佳 《科技通报》2014,(10)

网络病毒的入侵和传播通常伴随着强杂波信息的掩盖而提高其生存能力,研究一种有效的免疫算法是对抗病毒传播的关键。传统的抵御网络病毒传播的免疫方法采用人工免疫算法,该法基于熵权重属性分类时不能有效抵抗强杂波干扰的影响,抗病毒感染的免疫能力不高。本文提出一种基于自适应实时繁殖策略的灰阶菌群免疫算法,采用分段匹配白化滤波方法滤除杂波信息,构建强杂波环境下病毒传播数学演化模型,以信息熵作为病毒传播免疫分类属性,提出采用灰阶菌群聚类方法进行病毒特征免疫。进行仿真实验表明该算法能有效滤除病毒潜藏的杂波干扰,病毒信息特征菌群得到准确聚类,降低了计算机用户的感染率,实时性和稳定性好。  相似文献   

民航甚高频地空通信多径干扰的研究     

刘旭  谢来阳 《大众科技》2014,(10):43-45

文章介绍了民航甚高频地空通信的视距传播的特点,通过数学模型阐述了多径干扰的形成条件和对通信造成的影响,分析了多径干扰导致信号衰落出现的位置与地面站天线高度和飞行高度的关系,通过确定地面主反射点,计算地面天线高度与多径干扰时延的关系,探讨了天线高度对多径干扰时延的影响,研究如何抑制多径干扰。  相似文献   

Interferences from blood collection tube components on clinical chemistry assays     

Raffick A.R. Bowen  Alan T. Remaley 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(1):31-44

Improper design or use of blood collection devices can adversely affect the accuracy of laboratory test results. Vascular access devices, such as catheters and needles, exert shear forces during blood flow, which creates a predisposition to cell lysis. Components from blood collection tubes, such as stoppers, lubricants, surfactants, and separator gels, can leach into specimens and/or adsorb analytes from a specimen; special tube additives may also alter analyte stability. Because of these interactions with blood specimens, blood collection devices are a potential source of pre-analytical error in laboratory testing. Accurate laboratory testing requires an understanding of the complex interactions between collection devices and blood specimens. Manufacturers, vendors, and clinical laboratorians must consider the pre-analytical challenges in laboratory testing. Although other authors have described the effects of endogenous substances on clinical assay results, the effects/impact of blood collection tube additives and components have not been well systematically described or explained. This review aims to identify and describe blood collection tube additives and their components and the strategies used to minimize their effects on clinical chemistry assays.  相似文献   

浅析机械维修中过盈零件的装配     

杨继东 《科教文汇》2014,(18):120-120,135

在现代的机械生产和维修中,过盈配合零件的拆装比较常见,本文就机械维修过程中常见的过盈配合的零件安装和拆卸问题进行分类探讨。  相似文献