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31.
Appropriate intellectual property protection and economic growth in countries at different levels of development 总被引:1,自引:0,他引:1
This paper examines how the role of patents and utility models in innovation and economic growth varies by level of economic development. Using a panel dataset of over 70 countries, we find that patent protection is an important determinant of innovation and that patentable innovations contribute to economic growth in developed countries, but not in developing. Instead, in developing economies, a minor form of intellectual property rights (IPRs) - namely utility models - is conducive to innovation and growth, controlling for other factors. Using Korean firm level data as a case study, we find that utility model innovations contribute to firm performance when firms are technologically lagging and that those minor innovations can be a learning device and thus a stepping stone for developing more patentable inventions later on. Upon reaching higher levels of technological capabilities, firms become more reliant upon patents and less on utility models. Thus the lesson here is that patent protection enhances innovation and economic growth in countries where the capacity to conduct innovative research exists. Where this capacity is weaker, a system that provides incentives to conduct minor, incremental inventions is more conducive to growth. The significance of this paper is to emphasize the importance not just of the strength of IPRs but of the appropriate type of IPRs for economic development. 相似文献
32.
Wei Wang Li Wang Xin-xiu Li Xia Chen Hai-yan Zhang Yu He Jing-jing Wang Yong-yan Zhao Bao-le Zhang Yin-xue Xu 《Journal of Zhejiang University. Science. B》2010,11(9):719-727
Bone morphogenetic proteins (BMPs) play a critical role in the growth and steroidogenesis of granulosa cells (GCs). BMP signals
act through membrane-bound heteromeric serine/threonine kinase receptors. Upon ligand binding, BMPs activate intracellular
Smad proteins and regulate growth and apoptosis in various cell types. The objective of this study was to demonstrate the
effects of BMP/Smad signal on growth and steroidogenesis of porcine GCs. A strategy of RNA interference (RNAi)-mediated ‘gene
silencing’ of Smad4, a core molecule mediating the intracellular BMP/Smad signal transduction pathways, was used to interrupt
endogenous BMP/Smad signaling. Results indicate that Smad4-small interfering RNA (siRNA) caused specific inhibition of Smad4
mRNA and protein expression after transfection. Interrupted endogenous BMP/Smad signaling significantly inhibited growth,
and induced apoptosis of porcine GCs, while decreasing estradiol production. In addition, interrupted BMP/Smad signaling significantly
(P<0.05) changed the expression of Cyclin D2, CDK4, Bcl-2, and Cyp19a1. These findings provide new insights into how BMP/Smad signaling regulates the growth and steroidogenesis of porcine GCs. 相似文献
33.
旅游发展模式对旅游业的发展质量有重大影响,在不同的发展阶段应该选用不同的发展模式.黄山市现行数量增长型发展模式已经导致以下弊端:资源配置效率降低,旅游企业经济效益下滑;过度追求接待规模,往往造成生态环境恶化;无限制地扩大接待量,必然导致游客评价度降低:乡村旅游的低水平开发,无法给村民带来预期的经济收益与社会进步.黄山市必须分阶段推行效益增长型发展模式,其实施策略包括:第一,以科学合理的规划为指导,提高资源的配置效率;第二,以世界一流旅游目的地建设为目标,完善旅游产品体系,深度发掘旅游资源的经济价值:第三,进一步发挥屯溪的中心城市作用,提高黄山市旅游产业的集聚程度;第四,构建新型空问竞合模式,通过区域合作提升旅游目的地的影响力与竞争力. 相似文献
34.
刘军 《中国教育研究与创新》2006,3(11):26-29
本文围绕企业成长,立足企业家精神和专业化管理。分析了企业家和职业经理人融合的三种路径,揭示了“融合陷阱”的存在及其认识误区.进而提出.创业管理是企业家和职业经理人融合的新路径取向,并从企业内外部角度展望了公司企业家精神以及创业教育在企业家和职业经理人融合中的重要作用。 相似文献
35.
Study on pig growth hormone gene polymorphisms in western meat-type breeds and Chinese local breeds 总被引:1,自引:0,他引:1
INTRODUCTIONGrowthhormone (GH)isapeptidehormonewhichregulatesgrowthandvariousmetabolicac tivities (Sterle,1 995;Yuan ,1 996) .InjectionsofGHintogrowingpigsincreasedgrowthrateoftheanimalsandthepercentageofmuscle ,andwhilefataccretionwasdecreased (Bonneau ,… 相似文献
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38.
Touch your toes! Developing a direct measure of behavioral regulation in early childhood 总被引:6,自引:0,他引:6
Claire E. Cameron Ponitz Megan M. McClelland Abigail M. Jewkes Carol McDonald Connor Carrie L. Farris Frederick J. Morrison 《Early childhood research quarterly》2008
Behavioral aspects of self-regulation, including controlling and directing actions, paying attention, and remembering instructions, are critical for successful functioning in preschool and elementary school. In recent years, several direct assessments of these skills have appeared, but few studies provide complete psychometric data and many are not easy to administer. We developed a direct measure of children's behavioral regulation, the Head-to-Toes Task, and report performance of participants aged 36–78 months, including a group of Spanish-speaking children, from two different sites (N = 353; N = 92). We examined construct validity, examiner reliability, sources of variation, and associations between task scores and background characteristics. Results showed that the task was valid, reliable, and demonstrated variability in children's scores. A cross-classified hierarchical growth curve analysis indicated that girls, participants assessed in English, and higher-socioeconomic status (SES) children achieved slightly higher average scores than did boys, Spanish-speaking and lower-SES children, but effect sizes were small. Older participants achieved higher scores than did younger children, and there were no effects for site. Results suggest that the Head-to-Toes Task is an informative and easy-to-administer direct assessment of children's behavioral regulation. We discuss implications for its use in early childhood settings. 相似文献
39.
环境对个人的成长至关重要,而幼儿园是幼儿成长发展的重要环境。因此如何实现幼儿环境的高质量发展,是幼儿园发展的重要命题。本文笔者深入分析了幼儿园环境对幼儿成长的影响,提出了几点关键因素。 相似文献
40.
Few studies have examined the long-term relations between children's early spatial skills and their later mathematical abilities. In the current study, we investigated children's developmental trajectories of spatial skills across four waves from age 3–7 years and their association with children's later mathematical understanding. We assessed children's development in a large, heterogeneous sample of children (N = 586) from diverse cultural backgrounds and mostly low-income homes. Spatial and mathematical skills were measured using standardized assessments. Children's starting points and rate of growth in spatial skills were investigated using latent growth curve models. We explored the influence of various covariates on spatial skill development and found that socioeconomic status, language skills, and sex, but not migration background predicted children's spatial development. Furthermore, our findings showed that children's initial spatial skills––but not their rate of growth––predicted later mathematical understanding, indicating that early spatial reasoning may play a crucial role for learning mathematics. 相似文献