学生违规行为与教育性惩戒     

曹辉  陶静 《江苏教育研究》2011,(8):40-42

教育活动中学生的违规行为是多种多样的,包括在学校中的学生暴力现象、旷课逃学、扰乱课堂教学秩序等。由于教育惩戒的根本目的在于帮助学生明辨是非、改正错误,维持教育秩序、促进学生的社会化发展,因此,教育惩戒是纠正和控制学生违规行为的重要方式。教育性和制裁性是科学、理性的教育惩戒的核心特征。  相似文献   

教师文化品格建构的价值追问     

王晓春 《江苏教育研究》2011,(8):43-46

＂解放教师＂,是教师文化品格建构的核心策略,＂让教师站稳儿童立场,让教师生成教育智慧＂,这是＂解放教师＂所期望达成的价值目标。  相似文献   

儿童文学校本课程的开发：以兴趣为本     

刘华 《江苏教育研究》2011,(5):22-24

“孩子不感兴趣”是当前儿童文学校本课程开发中的主要问题。要解决这一问题,教师必须确立以兴趣为本的课程开发观．进而采用“基于孩子的阅读能力和情感需求推荐作品”,“以交流审美体验为中心安排语文实践活动”等课程开发策略。  相似文献   

经典童书与中小学写作教学     

高子阳 《江苏教育研究》2011,(5):35-39

我国中小学生一直害怕写作,而研究发现童书能让学生悟出“人为什么要写作”,教师稍微点一点学生就能懂得“作为一个人该怎样去写作”,再简单讲一讲孩子都能清楚“文章该写哪些内容”。这是一举多得、事半功倍的好事。在学生轻松阅读之中,教师稍微从写作方面点拨一下,就能唤醒学生,快速将其带进喜欢写作的浪潮中。  相似文献   

阿尔茨海默病发病机理的研究进展     

薛小燕  郭小华  李敏  罗焕敏 《河北北方学院学报(医学版)》2011,(6):37-47

阿尔茨海默病(Alzheimer’s disease,AD)病因及发病机制尚未完全阐明,有关其发病机制有β-淀粉样蛋白假说、Tau 蛋白假说、炎症学说和氧化应激学说等多种.本文就现有较公认的发病机制研究进展作一综述.  相似文献   

Effects of GLUT4 expression on insulin resistance in patients with advanced liver cirrhosis     

Shan WF  Chen BQ  Zhu SJ  Jiang L  Zhou YF 《Journal of Zhejiang University. Science. B》2011,12(8):677-682

  相似文献   

Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions     

Zhao Q  Liu ZD  Xue Y  Wang JF  Li H  Tang QJ  Wang YM  Dong P  Xue CH 《Journal of Zhejiang University. Science. B》2011,12(7):534-544

Ds-echinoside A (DSEA), a non-sulfated triterpene glycoside, was isolated from the sea cucumber Pearsonothuria graeffei. In vitro and in vivo investigations were conducted on the effects of DSEA on tumor cell adhesion, migration, invasion, and angiogenesis. In this study, we found that DSEA inhibited the proliferation of human hepatocellular liver carcinoma cells Hep G2, with a half-maximal inhibitory concentration (IC₅₀) of 2.65 μmol/L, and suppressed Hep G2 cell adhesion, migration, and invasion in a dose-dependent manner. DSEA also reduced tube formation of human endothelial cells ECV-304 on matrigel in vitro and attenuated neovascularization in the chick embryo chorioallantoic membrane (CAM) assay in vivo. Immunocytochemical analysis revealed that DSEA significantly decreased the expression of matrix metalloproteinase-9 (MMP-9), which plays an important role in the degradation of basement membrane in tumor metastasis and angiogenesis. DSEA also increased the protein expression level of tissue inhibitor of metalloproteinase-1 (TIMP-1), an important regulator of MMP-9 activation. From the results of Western blotting, the expressions of nuclear factor-kappa B (NF-κB) and vascular endothelial growth factor (VEGF) were found to be remarkably reduced by DSEA. These findings suggest that DSEA exhibits a significant antimetastatic activity through the specific inhibition of NF-κB-dependent MMP-9 and VEGF expressions.  相似文献   

An efficient method of addressing ectopic beats: new insight into data preprocessing of heart rate variability analysis     

Wen F  He FT 《Journal of Zhejiang University. Science. B》2011,12(12):976-982

Heart rate variability (HRV) analysis is affected by ectopic beats. An efficient method was proposed to deal with the ectopic beats. The method was based on trend correlation of the heart timing signal. Predictor of R-R interval (RRI) value at ectopic beat time was constructed by the weight calculation and the slope estimation of preceding normal RRI. The type of ectopic beat was detected and replaced by the predictor of RRI. The performance of the simulated signal after ectopic correction was tested by the standard value using power spectrum density (PSD) estimation, whereas the results of clinical data with ectopic beats were compared with the adjacent ectopic-free data. The result showed the frequency indexes after ectopy corrected had less error than other methods with the test of simulated signal and clinical data. It indicated our method could improve the PSD estimation in HRV analysis. The method had advantages of high accuracy and real time properties to recover the sinus node modulation.  相似文献   

RRM1 gene expression in peripheral blood is predictive of shorter survival in Chinese patients with advanced non-small-cell lung cancer treated by gemcitabine and platinum     

Wang LR  Zhang GB  Chen J  Li J  Li MW  Xu N  Wang Y  Shen Tu JZ 《Journal of Zhejiang University. Science. B》2011,12(3):174-179

Objective  

To evaluate the predictive values of gene expressions of ribonucleotide reductase M1 (RRM1) and breast cancer susceptibility gene 1 (BRCA1) in peripheral blood from Chinese patients with non-small-cell lung cancer (NSCLC) treated with gemcitabine plus platinum.  相似文献   

基于实证的中小学生学业质量分析报告——以江苏连云港市为例     

顾长明 《考试研究》2011,(6):13-21

中小学生学业质量是教育教学质量的重要组成部分,连云港市义务教育阶段学生学业质量监测与问卷实证数据的分析,反映出中小学学业质量整体达标率、优分率较好,学生基础知识与基本技能较为扎实,教与学方式发生深刻变化,学校办学行为进一步规范。同时,该报告也反映出学生解决问题能力不高、区域内质量不均衡、教师教学策略与本体知识缺失、学业质量背景环境不理想等问题。为此,本文提出要发挥质量监测功能、引领教学行为跟进、研发学业质量标准、推进教育现代化创建和完善质量监测反馈系统等建议,以引导学生、教师、学校、社会树立正确的教育观、教学观、评价观和质量观。  相似文献