Physical Activity Indicators,Metabolic Biomarkers,and Comorbidity in Type 2 Diabetes     

《Research quarterly for exercise and sport》2012,83(4):690-698

ABSTRACT

Purpose: This study aimed (1) to compare physical activity (PA) indicators, metabolic biomarkers, and comorbidity, (2) to investigate the relationship between PA indicators and metabolic biomarkers, comorbidity and (3) to identify barriers to PA in patients with type 2 diabetes (T2DM) who are using oral hypoglycaemic agent (OHA) or combined OHA and insulin (OHAiN). Methods: Sixty-one patients were classified as patients using only OHA or combined OHAiN. Metabolic biomarkers (waist-to-hip ratio, body mass index (BMI), lipid profile, glycosylated haemoglobin (HbA1c), fasting blood glucose, comorbidity and PA indicators (self-reported PA, number of steps (NOS), 6-minute walking distance (6MWD)) were assessed. PA perceptions and reasons for inactivity were questioned. Results: The comorbidity (p = .013), low-density lipoprotein-cholesterol (p = .026), total cholesterol (p = .008) and HbA1c (p = .020) were higher and PA level was lower (p = .007) in the OHAiN group. NOS was positively correlated with high-density lipoprotein-cholesterol (p = .037) and negatively correlated with BMI (p = .007). 6MWD was negatively correlated with BMI (p = .014) and comorbidity (p = .004) in the OHA group. BMI was a significant predictor of NOS (adjusted R² = 0.242) and comorbidity for 6MWD (adjusted R² = 0.250) in the OHA group. The majority of the patients (OHA = 34.3%, OHAiN = 42.3%) reported “lack of time” as the most common barrier to PA. Conclusions: This study showed that patients on OHAiN have lower PA levels, poorer metabolic profiles, and higher comorbidity rates than OHA users. PA indicators were related with some metabolic biomarkers and comorbidity in only OHA users. The most common reason for inactivity was “the lack of time” in both groups.  相似文献   

分段逆向调强优化方法在乳腺癌调强放疗计划设计中的应用研究     

靳富  柳先锋  何亚男  杨勇  王颖 《中国科技信息》2012,(17):48-49

目的:制作乳腺癌调强放疗计划时,采用分段逆向调强优化方法以达到更好的靶区剂量和保护肺、心脏等危及器官。方法:应用Eclipse8.6计划系统针对10例乳腺癌患者(肿瘤原发部位左右侧各5例)分别制定T1,T2模式调强放疗计划,处方剂量均为DT50Gy/25次。T1模式采用左乳300°、330°、0°、30°、60°、90°和120°方向射野,右乳60°、30°、0°、330°、300°、270°和240°方向射野,设置优化参数进行逆向优化和剂量运算。T2模式采用与T1模式相同的角度方向设野,第一段总剂量24Gy,分次剂量2Gy,分12次治疗,设置优化参数进行逆向优化和剂量运算;第二段总剂量26Gy,分次剂量2Gy,分13次照射,设置优化参数,采用"Base dose plan"功能选择基于第一段治疗计划以总量50Gy来逆向优化和剂量运算。将两段计划相加作为T2模式的治疗计划,通过剂量体积直方图比较两种模式下计划的靶体积和危及器官剂量分布。结果:T1、T2模式调强放疗计划的靶体积均满足临床剂量要求,对于左侧乳腺癌,适形指数分别为0.727±0.034、0.751±0.034(t=-6.20,P=0.003);对于右侧乳腺癌,适形指数分别为0.691±0.058、0.729±0.048(t=-5.39,P=0.006)。对左侧乳腺癌,T2模式的左肺V10(%)、左肺V20(%)、左肺V30(%)、全肺V10(%)、全肺V20(%)、全肺V30(%)和心脏V10(%)均大于T1模式,分别增大5.0%、2.7%、3.7%、4.6%、2.6%、3.8%和4.4%。对于右侧乳腺癌,无充分证据说明危及器官各指标有差别。结论:与T1模式相比,采用分段逆向调强优化方法能更好的优化靶区的剂量分布,但对左侧乳腺癌而言,会略微增加左肺、全肺和心脏剂量受量。  相似文献   

基于专利地图的治疗型超声竞争情报挖掘     

侯筱蓉  赵德春 《中国科技资源导刊 (中国信息导报)》2010,(4):61-65

通过专利地图分析专利信息,可以挖掘技术热点,预测技术发展方向,确定竞争对手及其地位。以治疗型 超声专利为例,通过对所有在我国申请的该类发明专利的统计,利用时间序列、统计频次、聚类等方法,绘制各类专利 地图,最终以鱼骨图这种可视化的方式进行汇总,直接展示情报分析结果,挖掘治疗型超声的相关竞争情报。将鱼骨图 与专利地图结合起来对专利情报进行分析,可以将竞争环境、竞争对手、研究热点等有效因素进行有条理的可视化展现。  相似文献   

Human biochemical genetics： an insight into inborn errors of metabolism     

Yu C  Scott CR 《Journal of Zhejiang University. Science. B》2006,7(2):165-166

Inborn errors of metabolism （IEM） include a broad spectrum of defects of various gene products that affect intermediary metabolism in the body. Studying the molecular and biochemical mechanisms of those inherited disorder, systematically summarizing the disease phenotype and natural history, providing diagnostic rationale and methodology and treatment strategy comprise the context of human biochemical genetics. This session focused on： （1） manifestations of representative metabolic disorders; （2） the emergent technology and application of newborn screening of metabolic disorders using tandem mass spectrometry; （3） principles of managing IEM; （4） the concept of carrier testing aiming prevention. Early detection of patients with IEM allows early intervention and more options for treatment.  相似文献   

A social skills group for children     

Estelle Macdonald  Uttom Chowdhury  Jackie Dabney  Miranda Wolpert  Samuel M. Stein 《Emotional and Behavioural Difficulties》2013,18(1):43-52

Abstract

An NHS Trust set up groups to teach social skills to children and adolescents using a cognitive behavioural framework. One group of seven children (five boys and two girls) is described. Parents were invited to a parallel parents' group. Each group lasted for 90 minutes and ran weekly for 6 weeks. Extensive liaison with parents and teachers took place before, during and after the group. Analysis of pre- and postgroup questionnaires sent to parents and teachers indicated improved social functioning, outside the group, for most of the children. Parents valued the dialogue with professionals and often felt supported by them for the first time. Therapists' contact with teachers ensured full knowledge of children's behaviour and the transfer of skills to schools. Cognitive behavioural techniques with children under-going group work require intensive liaison to facilitate generalization of skills learnt.  相似文献   

The effect of music therapy services on classroom behaviours of newly arrived refugee students in Australia—a pilot study     

Felicity Baker  Carolyn Jones 《Emotional and Behavioural Difficulties》2013,18(4):249-260

This pilot study examined the effects of a short‐term music therapy program on the classroom behaviours of newly arrived refugee students who were attending an intensive ‘English as a Second Language’ secondary school. A cross‐over design with two five‐week intervention periods was employed with group music therapy sessions conducted one or two times per week. Data from the Behaviour Assessment Scale for Children were used to evaluate a range of positive and negative school behaviours. A significant decrease in externalising behaviours was found with particular reference to hyperactivity and aggression. No significant differences were found in other behaviours. Explanations and implications of these findings are discussed.  相似文献   

Connecting to the Good Life through outdoor adventure leadership experiences designed for Indigenous youth     

Stephen D. Ritchie  Mary Jo Wabano  Rita G. Corbiere  Brenda M. Restoule  Keith C. Russell  Nancy L. Young 《Journal of Adventure Education & Outdoor Learning》2013,13(4):350-370

Indigenous voices are largely silent in the outdoor education and adventure therapy literature. The purpose of this research collaboration was to understand how a 10-day outdoor adventure leadership experience (OALE) may promote resilience and well-being for Indigenous youth through their participation in the program. The process was examined through a community-based participatory research project that sought insight from the perspectives of one First Nations community in Canada. The OALE was implemented with six different groups for a total of 43 youth participants (ages 11.9–18.7 years) from Wikwemikong Unceded Indian Reserve in northeastern Ontario. Field data were collected from multiple sources including participant interviews, journals, focus groups, and talking circles. Using a critical ethnographic lens, we analyzed the data inductively to understand how the OALE promoted resilience and well-being. We listened to Indigenous voices, adhered to principles of Indigenous coding for thematic content and respected Indigenous ways of knowing for interpreting results. The process of connecting to the Good Life (Anishinaabe Bimaadziwin) or waking up (nsidwaaswok) to the Good Life emerged as the dominant theme. Connecting to the Good Life may offer a simple yet compelling way to understand the net impact of the OALE.  相似文献   

便携式两轴跟踪转台结构及控制系统的设计     

彭凡林 《九江职业技术学院学报》2013,(4):14-16

主要对跟踪转台的伺服控制系统进行了设计和研究,阐述了跟踪转台的工作原理及其功能。综合考虑到一些影响转台稳态精度和动态性能的因素后,采用两环反馈来设计控制系统从而完成了对整个伺服控制系统的硬件和软件的整体设计。  相似文献   

音乐沙盘疗法的理论研究     

姜添 《合肥教育学院学报》2013,(5):119-121

音乐疗法作为艺术疗法的一种,对心理治疗的影响已毋庸置疑,而沙盘游戏作为新兴的治疗理论也广泛地得以实践。音乐治疗和沙枯游戏虽然处在不同的领域,但两者的理论背景都有相似之处。研究试图从不同的心理学理论出发,尝试分析和探索音乐治疗与沙盘游戏结合起来实践的可能性。  相似文献   

一例一般心理问题的咨询案例分析     

王淑华 《丽水学院学报》2013,35(3):72-75

本案例中,来访者因为网恋受骗而形成了创伤,沉浸于对男朋友的憎恨之中,又因为自身性格及身边的环境而未能获得很好的疏导,从而沉浸于压抑的情感中不能自拔,严重影响了生活和工作。在咨询过程中,咨询师根据来访者的主诉及对她的观察判断,将其诊断为重大生活事件应激方面的问题。在咨询中,咨询师在精神分析理论的基础上,使用认知领悟疗法以及空椅技术、释梦等技术针对来访者进行了有效的咨询,使来访者解决了面临的问题。  相似文献