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62.
图片命名、范畴流畅性等神经心理学测验表明,阿尔兹海默症(AD)患者普遍存在语义记忆的损伤,并随着病程的发展表现出进行性与弥散性特点。AD患者语义记忆的损伤既可能由语义知识的存储障碍造成,也可能由语义知识的提取障碍引发,还可能由存储与提取的双重损伤造成。未来研究应开发出对早期AD检测更为敏感的语义记忆测验,并采用横向与纵向多种研究技术与手段,考虑不同语言文化背景下AD患者语义损伤的情况,以综合分析AD患者语义记忆损伤的实质及其发展趋势。 相似文献
63.
烟碱对豚鼠及兔乳头状肌电活动的RP,APA和Vmax无明显影响;但对其复极时程则因浓度不同,而呈延长或缩短双相效应。高浓度烟碱(604μmol/L使APD_(85),APD_(90)和ERP分别延长27.3,26.0及26.1%;而低浓度(0.6μmol/L)使三者分别缩短49.6,40.0及27.6%。烟碱对慢电位的影响,表明可能高浓度烟碱促进Ca~(2 )内流;低浓度则抑制Ca~(2 )内流。 相似文献
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Cell therapy in congestive heart failure 总被引:5,自引:0,他引:5
Congestive heart failure (CHF) has emerged as a major worldwide epidemic and its main causes seem to be the aging of the population and the survival of patients with post-myocardial infarction. Cardiomyocyte dropout (necrosis and apoptosis) plays a critical role in the progress of CHF; thus treatment of CHF by exogenous cell implantation will be a promising medical approach. In the acute phase of cardiac damage cardiac stem cells (CSCs) within the heart divide symmetrically and/or asymmetrically in response to the change of heart homeostasis, and at the same time homing of bone marrow stem cells (BMCs) to injured area is thought to occur, which not only reconstitutes CSC population to normal levels but also repairs the heart by differentiation into cardiac tissue. So far, basic studies by using potential sources such as BMCs and CSCs to treat animat CHF have shown improved ventricular remodelling and heart function. Recently, however, a few of randomized, double-blind, placebo-controlled clinical trials demonstrated mixed results in heart failure with BMC therapy during acute myocardial infarction. 相似文献
68.
Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention 总被引:2,自引:0,他引:2
Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion. 相似文献
69.
<正>排球是一项对人体要求相当全面的运动,具有明显的耐力性特点,同时对力量、速度、柔韧和灵敏等素质也有很高的要求。因此,排球运动中经常伴有大强度的爆发性动作,有时也会导致运动性损伤,应多加注意预防。一、排球运动中经常损伤的部位排球运动作为一项技能性要求很高的竞技 相似文献
70.
运动损伤指在运动过程中所发生的各种损伤.通过文献资料和实践经验分析体育训练中运动损伤产生的原因及预防对策,为体育教学提供参考. 相似文献