松寿丹对实验性心脑缺氧的保护作用     

赵洪良  张隆  程建贞  王晓春  张力 《河北北方学院学报(医学版)》1994,(3)

本实验对松寿丹(SSD)对实验性小鼠心脑缺氧的保护作用及与血脂的关系进行了研究。实验结果证明:①SSD对NaNO_2中毒所致急性血液性缺氧有保护作用,1.6g/kgP<0.05;②能显著降低高脂饲养动物血清胆固醇含量,0.8g/kg和0.4g/kg两组均P<0.01;③对高脂饲养动物耐NaNO_2缺氧有保护作用,0.8g/kg组P<0.05。提示松寿丹不仅对单纯血液性缺氧有保护作用,而且还通过其显著的降血脂作用改善循环性缺氧,提高机体耐缺氧能力。  相似文献   

6周有氧运动改善不同程度肥胖青少年体质健康的研究     

潘丽英  马春莲  谷涌泉 《武汉体育学院学报》2022,56(7):76-83

目的:研究有氧运动对不同程度肥胖青少年形态、机能、糖脂代谢及身体素质的影响,探索非医疗运动手段治疗青少年肥胖的可行性方法。方法:招募50名13~19岁肥胖青少年,依据BMI值分别纳入中度或重度肥胖组,每组25人。两组受试者进行6周有氧运动(5days/week,50min/day),在运动前、运动3周和6周后分别测试受试者的身体形态、基础生理机能、糖脂代谢和身体素质等指标,并对以上数据进行统计学分析。结果:3周和6周运动均显著降低两肥胖组的体重、BMI、腰围、臀围、脂肪量、体脂率、血脂、甘油三酷、血清胰岛素水平和胰岛素抵抗指数(P＜0.05或P＜0.01),下调重度肥胖组的低密度脂蛋白水平(P＜ 0.01),提高两组肺活量、肺活量指数和50 m跑、俯卧撑、坐位体前屈成绩(P＜ 0.05);6周运动还能进一步提高两组的1 000 m跑、平衡能力以及重度肥胖组的瘦体重和高密度脂蛋白水平(P＜0.05或P＜0.01),下调两组的基础代谢率(P＜0.05)。结论:3周有氧运动就能有效改善肥胖青少年的体质健康,运动改善体质健康的效应呈时间依赖性增加的模式,并且重度肥胖者相比中度肥胖者对有氧运动更加敏感。  相似文献   

运动员的运动能力和脂类、蛋白质的关系   总被引：1，自引：0，他引：1  

杨世娣  邓九斤 《淮南职业技术学院学报》2005,5(4):26-27,78

随着现代科学技术的突飞猛进和体育事业的日益发展，营养在体育运动中的作用和地位越来越受到人们的关注，由于运动员在训练和比赛中消耗能量较多，只有给予及时补充，才能满足正常需要，因此，合理的营养补充对运动员来说，是提高运动成绩，增强体力快速恢复，以取得良好运动训练效果的物质保证；脂肪、蛋白质在运动训练时起着重要的供能作用，它是运动员保持最佳身体和竞技状态的物质基础，对运动成绩有直接的影响；根据多年训练实践，就运动员的运动能力与脂类、蛋白质的相互关系进行探讨，以便为运动员在训练和比赛后的快速恢复及保持竞技状态进行合理营养补充和膳食安排。  相似文献   

Oxidative Stress Correlates with Complications Among Diabetic Patients Attending a Diabetic Clinic in Muhimbili National Hospital, Dar es Salaam, Tanzania     

Solomon Genet  Yakobo Lema  Janne Lutale 《Indian journal of clinical biochemistry : IJCB》2013,28(2):177-180

In diabetes, persistent hyperglycemia results in increased production of free radicals especially oxygen free radicals, which can cause cell destruction and tissue injury resulting in cell dysfunction. With the premise that oxidative stress is a major cause of diabetic complications, we conducted a controlled laboratory based investigation on level of lipid peroxide levels in the serum of Type 1 and Type 2 diabetic patients attending Muhimbili National Hospital. From our clinical data it was observed that majority of the patients had higher waist to hip ration and body mass index, which suggests that the patients were either overweight or obese. The enrolled diabetic patients had higher lipid peroxide levels than controls and also Type 2 patients had higher lipid peroxide levels than Type 1 patients. Moreover, patients with known complications had higher lipid peroxide levels than patients without complications. The lipid peroxide levels in the diabetic patients were significantly different from that of the control subjects enrolled in the study. A majority of the diabetic patients had a poorly controlled blood sugar. Our finding hints that despite the fact that diabetic patients in our clinic are on follow up, they are at a risk of developing coronary heart diseases, neuropathy and other secondary diabetic complications.  相似文献   

The influence of 2 weeks of low-volume high-intensity interval training on health outcomes in adolescent boys     

Alan R. Barker  Josephine Day  Aaron Smith  Bert Bond  Craig A. Williams 《Journal of sports sciences》2013,31(8):757-765

Abstract

The present study aimed to establish whether 2 weeks of high-intensity interval training would have a beneficial effect on aerobic fitness, fat oxidation, blood pressure and body mass index (BMI) in healthy adolescent boys. Ten adolescent boys (15.1 ± 0.3 years, 1.3 ± 0.2 years post-estimated peak height velocity) completed six sessions of Wingate-style high-intensity interval training over a 2-week period. The first session consisted of four sprints with training progressed to seven sprints in the final session. High-intensity interval training had a beneficial effect on maximal O₂ uptake (mean change, ±90% confidence intervals: 0.19 L · min^?1, ±0.19, respectively), on the O₂ uptake at the gas exchange threshold (0.09 L · min^?1, ±0.13) and on the O₂ cost of sub-maximal exercise (–0.04 L · min^?1, ±0.04). A beneficial effect on the contribution of lipid (0.06 g · min^?1, ±0.06) and carbohydrate (–0.23 g · min^?1, ±0.14) oxidation was observed during sub-maximal exercise, but not for the maximal rate of fat oxidation (0.04 g · min^?1, ±0.08). Systolic blood pressure (1 mmHg, ±4) and BMI (0.1 kg · m², ±0.1) were not altered following training. These data demonstrate that meaningful changes in health outcomes are possible in healthy adolescent boys after just six sessions of high-intensity interval training over a 2-week period.  相似文献   

有氧运动对大鼠血糖、血脂和血液凝固功能的影响   总被引：3，自引：0，他引：3  

章罗庚 《北京体育大学学报》2009,(7)

目的:研究有氧运动(游泳)对大鼠血糖、血脂和血液凝固功能的影响。方法:30只SD大鼠进行不同强度的游泳训练后,测定其血糖、血脂、血浆组织因子(TF)活性、组织因子途径抑制物(TFPI)抗原、组织型纤溶酶原激活物(t-PA)和纤溶酶原激活剂抑制物-1(PAI-1)的活性。结果:1)与对照组相比,运动对大鼠血糖有降低趋势,但差异无统计学意义(p>0.05);2)小强度运动使大鼠血清LDL明显降低(p<0.05),大强度运动具有升高血清LDL的趋势;3)小运动组大鼠血清HDL浓度呈逐渐升高趋势,而大强度组的大鼠血清HDL明显降低(p<0.05);4)小强度游泳运动后,血浆t-PA活性及t-PA/PAI-1比值明显升高(p<0.01),PAI-1活性却明显降低(p<0.05);大强度游泳运动组t-PA活性没有明显改变,PAI-1活性有所升高;5)与对照组相比,运动训练使TFPI水平升高,其中小强度组TFPI含量(p<0.05)和TFPI/TF比值显著性升高(p<0.01),大强度组的TF含量有所升高,而TFPI/TF比值变化不明显(p>0.05)。结论:小强度的运动训练可以改善机体的凝血和纤溶功能,而大强度的训练不利...  相似文献   

力竭游泳对大鼠肠组织MDA、游离巯基和ATP含量的影响     

常波  麻新远  衣雪洁 《北京体育大学学报》2010,(5)

探讨力竭性运动引起的氧化应激对肠功能的影响及运动性肠功能紊乱的原因,32只SD雄性大鼠随机分为4组:即对照组(C);运动后即刻组EX;运动后30 min组(EX30);运动后60 min组(EX60),测定力竭性游泳后不同时相,肠组织匀浆MDA、游离巯基(Free-SH)和ATP含量。结果显示,运动后肠组织MDA含量在运动后30 min,60 min显著性增加(P0.01);运动后Free-SH含量在运动后30min(P0.05)和运动后60 min后(P0.01)显著下降;运动后30 min组ATP含量显著下降(P0.01)。结果提示,运动源性自由基产生增加,使得肠组织中游离巯基被氧化,导致ATP含量下降,可能是造成运动性肠功能紊乱的重要因素之一。  相似文献   

RBC membrane composition in insulin dependent diabetes mellitus in context of oxidative stress     

Gauri S. Vahalkar  Vijaya A. Haldankar 《Indian journal of clinical biochemistry : IJCB》2008,23(3):223-226

Glyco-oxidation is considered as a source of permanent, cumulative, oxidative damage to long lived proteins in ageing and in diabetes. Although RBC depends solely on glucose for energy purpose, hyperglycemic state glycosylates hemoglobin, creates oxidative stress and puts the cellular components at risk. In view of this, RBC membrane composition was analyzed in diabetic patients. The results were compared with healthy age and sex matched control groups. When RBC membrane components such as protein, sialic acid, phospholipids and cholesterol were determined in insulin dependent diabetes mellitus, a significant rise in phospholipids and cholesterol and significant fall in sialic acid and protein content was noted. RBC membrane composition showed pronounced alterations in insulin dependent diabetes mellitus. These changes were accompanied by higher levels of lipid peroxidation products like Malondialdehyde.  相似文献   

Effect of short term vitamin E supplementation on lipid peroxidation in acute myocardial infarction     

A. P. Jain  A. Mohan  O. P. Gupta  U. N. Jajoo  S. P. Kalantri  L. M. Srivastava 《Indian journal of clinical biochemistry : IJCB》1998,13(2):119-122

In view of sufficient body of evidence to substantiate the role of free radical mediated oxidative injury in myocardial infarction (M.I.), the utility of exogenous supplementation with antioxidant substance, vitamin E was studied. Forty patients of acute myocardial infarction were divided into two equal groups, one who received vitamin E and the other who did not. Plasma MDA levels showed a reduction in patients of M.I. who received vitamin E as well as in those who did not, however, the decrease was significantly more in the vitamin E treated subgroup.  相似文献   

逐级递增负荷后尿自由基代谢的变化及其与气体代谢的关系   总被引：1，自引：0，他引：1  

刘建红  周志宏 《西安体育学院学报》1999,16(1):0

采用递增运动负荷方式的研究方法,对３０名运动员随机分成两组,一组运动到个体无氧阈水平,一组运动至力竭。以探讨不同强度急性运动对尿中自由基（ＬＰＯ）血过氧化氢酶（ＣＡＴ）活性的影响,及其与气体代谢的关系。结果发现：无氧阈运动组尿ＬＰＯ和血ＣＡＴ活性无明显变化,力竭运动组在运动后尿中身自由基水平和血过氧化氢酶活性明显增加（Ｐ＜００５）,力竭运动组在运动后尿中自由基水平和血过氧化氢酶活性明显增加（Ｐ＜００５）,力竭运动后机体通气量（Ｖｅ）、吸氧量（ＶＯ２）和相对吸氧量（Ｖｏｚ／ｋｇ）明显高于无氧阈运动组。表明尿中自由基水平受运动强度和时间的影响,且与机体气体代谢关系十分密切  相似文献