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61.
青年编委组为《药物不良反应杂志》编委会的辅助组织和后备队伍,受编委会领导.在编委会的指导下,青年编委在组稿、撰稿和组织学术交流活动等方面均发挥了积极作用.一方面,青年编委组的建立,扩大了编委的组织从而扩大了杂志的影响,扩大了审稿专家队伍从而加快了审稿速度,扩大了作者队伍从而增加了优质稿源;另一方面,建立青年编委队伍,也给青年医学及药学工作者提供了成长和进步的平台、施展才能的舞台,对于杂志的后续发展是不可忽视的重要力量.  相似文献   
62.
安徽部分地区鸡球虫对六种药物的抗药性研究   总被引:3,自引:0,他引:3  
选择56只土杂鸡,检测了采自安徽部分地区的7种艾美耳球虫对6种常用抗球虫药的敏感性。根据最适抗球虫活性百分率、病变记分减少率和相对卵囊产量3项指标综合判定,安徽部分地区的柔嫩艾美耳球虫、毒害艾美耳球虫、巨型艾美耳球虫、堆型艾美耳球虫、和缓艾美耳球虫、早熟艾美耳球虫和哈氏艾美耳球虫的7个混合种对地克珠利、尼卡巴嗪、托曲珠利、磺胺喹噁啉钠、磺胺氯吡嗪钠和盐霉素钠均存在不同程度的抗药性,其中对盐霉素钠、地克珠利和托曲珠利具有重度抗药性,对尼卡巴嗪、磺胺喹噁啉钠和磺胺氯吡嗪钠具有中度抗药性。  相似文献   
63.
中国共产党禁毒政策法制化是推进我国禁毒工作法制化和禁毒政策科学化的现实需要。主要包括禁毒政策指导思想和禁毒观念法治化、禁毒政策内容法律化、禁毒政策过程合法化和执行环境法制化等内容。实现禁毒政策法制化的主要路径有:完善禁毒立法及禁毒法律法规实施的监督机制,加强禁毒管理制度体系建设,提高依法依规管理禁毒工作事务和依法行政的能力,加强禁毒法制的宣传教育和理论研究等。  相似文献   
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65.
Simple and sensitive Liquid Chromatography-Tandem Mass Spectrometry (LCMS/MS) method was developed and validated, then was implicated on hypertensive human subjects to study drug interaction of atorvastatin (ATVS) and Olmesartan (OLM) on status of Angiotensin-II (ANG-II). The ANG-II in plasma was extracted with 5 mL methanol containing 5 % formic acid through C18 (cartridges) liquid–liquid extraction, dried and reconstituted with 1 mL of 16 % acetonitrile in 0.1 % formic acid in water. The chromatographic separation of ANG-II with a Agilent technology 6410 Triple quadrupole was carried multiple reaction monitoring scan mode with a Agilent 1290 Infinity LC system for UHPLC. The sample were separated on a (Thermo Scientific) Hy-Purity advance (50 × 4.6 mm, 5 μm) using Mobile Phase A: 16 % acetonitrile in 0.1 % formic acid in water and Mobile Phase B: 0.1 % formic acid in methanol at a flow rate of 0.3 mL/min, performed at ambient temperature. The mobile phase gradient of 16 % acetonitrile in water was linearly increased to 38 % acetonitrile over 10 min and subsequently the mobile-phase was increased to 100 % acetonitrile over 15 min. The developed method was validated for specificity, accuracy, precision, stability, linearity, sensitivity and recovery. The method was linear between peak area ratio of standard and internal standard over the range of 50–800 ng/mL. The method was successfully applied for the drug interaction study revealed levels of ANG-II were significantly higher in ATVS + OLM treatment condition as compared to individual treatment of OLM. This reflects the reason of low effectiveness of ATVS + OLM in combination instead of synergistic activity.

Electronic supplementary material

The online version of this article (doi:10.1007/s12291-014-0457-x) contains supplementary material, which is available to authorized users.  相似文献   
66.
在深入剖解药品监管部门经费短缺且能力不足、制药企业刻意隐瞒、其他药评资料私密化等导致传统药监实效不彰之动因的基础上,阐明大数据环境下广域数据挖掘在实现药监元数据巨量化、引领药效认知科学化、减少涉药违规行为等方面的重要价值,提出包括改进用药数据挖掘技术、构筑病患信息加密认证系统、完善相关政策法规、适用惩罚性赔偿制度及提高第三方公开药评的物质奖励等在内的一系列推进药品监管数字化的具体举措。  相似文献   
67.
Using a quasi-experimental research design to test the “Marshall Hypothesis,” we investigated the effects of reading Michelle Alexander’s The New Jim Crow: Mass Incarceration and the Age of Colorblindness on college students’ views of drug policy in the United States. One hundred and twenty-eight undergraduate students at a predominantly white Midwest university took part in this study. Test subjects read the text and took both a pre- and posttest questionnaire, while a control group of students, who did not read the book, was also surveyed concerning their views on drug policies. Additionally, reflective essays written by the test population were also analyzed. Findings offer limited support for the Marshall Hypothesis, which asserts that a properly informed constituency would conclude that certain policies in the U.S. are unjust. Students, in general, showed significant changes in their perceptions of drug policies after reading the text. However, disaggregating students by gender showed that female students, more than male students, are more convinced by Alexander’s arguments that current drug policy unfairly target communities of color.  相似文献   
68.
与作为文学家、思想家的鲁迅研究相比,作为学者的鲁迅研究亟须进行。2008年鲁迅与学术研究主要在四个向度展开:对于"抄袭"公案的考辨、对于《中国小说史略》的批评与指正、对于《汉文学史纲要》的阐发和对于《魏晋风度及文章与药及酒之关系》的研究。  相似文献   
69.
近年来,我国特殊妇女人群贩毒问题日益突出。运用宽严相济刑事政策研究特殊妇女人群贩毒问题,预防、控制和打击、处理特殊妇女人群犯罪,是司法实践中亟待解决的问题。文章结合云南省临沧市边境缉毒工作的实际情况,从运用宽严相济刑事政策的视角,通过对临沧市一段时期特殊妇女人群贩毒问题的特点及原因的分析,提出处理特殊妇女人群贩毒问题的对策与建议。  相似文献   
70.
The aim of this study was to examine: 1) whether sport supplement use is related to doping and 2) whether sport supplement beliefs mediated this relationship. In Study 1, athletes (N = 598), completed measures of sport supplement use, sport supplement beliefs, and doping attitudes. In Study 2, athletes (N = 475) completed measures of sport supplement use, sport supplement beliefs, and doping likelihood. In both studies, sport supplement use predicted doping outcomes indirectly via sport supplement beliefs. Our findings provide novel evidence to suggest that sport supplement users, who strongly believe that sport supplements are effective, are more likely to dope. For anti-doping organisations wishing to prevent doping, targeting an athlete’s beliefs about sport supplements may improve the effectiveness of anti-doping prevention programmes.  相似文献   
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