Bilingual education through a pluri-centric approach: A case study of the effects of simultaneously learning two languages on L1 and L2 reading and writing proficiency     

《Studies in Educational Evaluation》2020

Language education has often been conducted based on monoglossic ideologies that keep L1 and L2 separate, a practice that receives growing criticism as out of sync with today’s multilingual globalized world. Informed by interdependence hypotheses and translanguaging theory, this research study explored the effects of a pluri-centric approach to learning L1 and L2 simultaneously. Through a bilingual intervention course with data collected from interviews, parents’ logbooks, observation field notes, questionnaires, and L1 and L2 reading and writing tests, this case study (n = 9) revealed that the approach effectively improved learners’ L1 and L2 proficiency, learning behaviour outside the classroom, self-efficacy, and confidence. Overall, the participants also perceived the bilingual course as effective, efficient, and innovative. The study provides a basis to reflect upon transferrable skills and core underlying proficiency as powerful concepts to draw upon in enhancing bilingual proficiency and effecting positive changes in learners’ behaviour and psychological well-being.  相似文献   

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

Evaluating solutions to the problem of false positives     

Thomas Gall  Zacharias Maniadis 《Research Policy》2019,48(2):506-515

A current challenge for the scientific community is the choice of appropriate policies to reduce the rate of false positives. Existing proposals differ in whether to prioritize tackling omission through transparency requirements, punishing more severe transgressions, or possibly both. We use a formal model to evaluate these possible solutions. We find that a policy that prohibitively increases the cost of ‘misdemeanor’ types of questionable research practices robustly decreases the overall rate of researcher misconduct, because the rate of ‘felonies’, such as fabrication, also decreases. Therefore proposals that aim to prevent lying by omission by enforcing reporting guidelines are likely to be effective in reducing researcher misconduct, but measures such as government audits (purported to counteract pure fraud) can backfire. Moreover, we find that an increase in the rewards of publication need not increase overall misconduct.  相似文献   

低负荷加压训练改善自发性高血压大鼠的血压效果及机制研究     

谭朝文  赵彦  俞莹莹  马晓缓  郑玉婵 《体育科学》2020,(3):46-53,63

目的:探究低负荷加压训练对自发性高血压大鼠的降压效果及其作用机制。方法:选取4周龄雄性自发性高血压大鼠,随机分为对照组(高血压安静组)、低负荷训练组、低负荷加压训练组和高负荷训练组。低负荷训练组进行35%~55%1RM递进式低负荷爬梯训练,低负荷加压训练组进行30%~40%血流受限结合35%~55%1RM递进式低负荷爬梯训练,高负荷训练组进行55%~75%1RM递进式高负荷爬梯训练,训练后测定血压、血液中内皮素-1、血管内皮生长因子、一氧化氮合成酶的表达和心肌组织中内皮型一氧化氮合成酶的表达。结果:1)与对照组、高负荷训练组相比,低负荷加压训练组收缩压、舒张压显著下降(P<0.05);与低负荷训练组相比,低负荷加压训练组舒张压显著下降(P<0.05)。2)与对照组相比,低负荷加压训练组血液中内皮素-1表达显著下调(P<0.05),血管内皮生长因子和一氧化氮合成酶表达显著上调(P<0.05);3)与对照组相比,低负荷加压训练组心肌中内皮型一氧化氮合成酶表达显著上调(P<0.05);4)在低负荷加压训练组中,收缩压与内皮素-1呈正相关,相关性分析具有统计学意义(P<0.05);收缩压与一氧化氮合成酶、血管内皮生长因子、内皮型一氧化氮合成酶均呈负相关,相关性分析具有统计学意义(P<0.05)。结论:1)低负荷加压训练降压效果优于高负荷训练;2)低负荷加压训练能够通过下调血液中内皮素-1的表达,上调血液中血管内皮生长因子和一氧化氮合成酶的表达,同时上调心肌中内皮型一氧化氮合成酶表达,改善内皮细胞功能,达到降压的效果。  相似文献   

基于Sentinel-1/2的水体提取方法对比研究——以斯里兰卡小型水体为例     

周晗  叶虎平  魏显虎  张宗科  王法溧  齐永菊  马建如 《中国科学院大学学报》2019,36(6):794-802

地表水面精确提取是研究地表水质和水量变化的重要基础。斯里兰卡是"21世纪海上丝绸之路"的重要参与国，年降雨量丰富，但时空分布不均，斯里兰卡人民长期用水困难，研究斯里兰卡地表水体有助于斯里兰卡民生问题的解决。斯里兰卡国内散布着大量的小型水库和坑塘，这些小面积水体易受周边环境因素影响而提取困难。基于2017年7月斯里兰卡中东部地区的哨兵（Sentinel）1/2号卫星影像，对比分析单波段法、水体指数法和监督分类等水体提取方法的精度和存在的问题。结果表明，归一化水体指数法NDWI的准确率最高，分类精度达94%。  相似文献   

基于负样本多通道优化SSD网络的钢铁厂提取     

卢凯旋  李国清  陈正超  昝露洋  李柏鹏  高建威 《中国科学院大学学报》2020,37(3):352-359

准确提取钢铁厂对去产能监测和环境保护具有重要意义。传统的人工目视解译方法效率低、成本高，无法满足开展大区域钢铁厂监测的需求。以深度学习目标检测网络SSD为基础，构建面向遥感影像钢铁厂提取的深度学习目标检测网络，提出maxout模块，将负样本通路优化为多分支结构，突出难分负样本特征并提升网络对无用特征的抵制效果。利用国产GF-1数据对京津冀地区的钢铁厂进行快速自动提取实验。与人工解译的钢铁厂点位数据的对比表明，该目标检测方法的提取精度达到80%以上。  相似文献   

基于系统性文献回顾法的新型研发机构研究与展望     

张玉磊  郑奕  罗嘉文  张光宇 《科技管理研究》2019,39(15)

本文以国内经济管理领域 2003年至2019 年的179篇文献为样本，使用系统性文献回顾法(SLR)，探索和总结了新型研发机构的研究现状及其知识结构，分析现有研究的缺失并尝试寻找未来的研究趋势。研究发现: 第一，新型研发机构的知识结构由9个部分构成一个2W1H的主题研究框架。第二，从国家、产业和企业层面分别总结了阻碍新型研发机构发展的因素及其提升对策建议。第三，从研究知识模块、研究切入角度和研究趋势拓展3个方面解剖现有知识断层，并对未来的研究提出具体可行的对策建议  相似文献   

TRIPS与我国专利权司法保护的发展     

冉传慧 《齐齐哈尔师范高等专科学校学报》2003,22(1):15-17

我国的专利制度从无到有，从不完善到完善，这一过程中，有关知识产权的国际条约，特别是《与贸易有关的知识产权协议TRIPS》对我国的专利立法产生了重大影响．我国第一部专利法自1984年颁布以来，在短短的不到20年的时间就建立起了一些发达国家经历了几十，上百年才完成的健全的专利保护制度，这一成就令世人注目。本着重探讨TRIPS协议对中国专利权司法保护的影响及历史背景。  相似文献   

生命教育论   总被引：1，自引：0，他引：1  

文雪 《黄石理工学院学报(人文社科版)》2002,(2)

教育培养人,意味着教育应当关注受教育者作为生命个体的真实存在。生命教育应成为现代教育反思的起点之一。教育关注个体的生命存在就应当认识生命、敬畏生命、尊重生命、热爱生命,进而提升生命。生命教育应成为教育内涵的一部分。  相似文献   

Influence of Magnetic Field on the Rectification Process of Binary Heterogeneous Azeotrope     

贾绍义  吴松海李真 贾亮 《天津大学学报(英文版)》2005,11(4):240-244

To improve separate effect of binary heterogeneous azeotrope in the magnetic field with different magnetic induction intensity, the influence of magnetic field on the rectification process of binary heterogeneous azeotrope was investigated with l-butanol-water system. The results show that the composition of liquid-liquid phase equilibrium of l-butanol-water system has definitely changed, the composition of l-butanol in light phase （l-butanol layer） increases by 1. 17%-1.63% and the composition of water in heavy phase （water layer） increases by 1.21%-1.58% under the influence of magnetic field. By separation of magnetization, the composition of l-butanol increases by 0.8%-1.2% and the recovery ratio of 1 -butanol increases by 1.6%-2.5%. Magnetic field has positive effect, however, the magnetized effect is not in proportion to magnetic induction intensity and has an optimum condition, in the range of 0.25 T-0. 3 T.  相似文献