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田径运动是所有运动的基础运动,是促进身体健康的重要手段,对实现健康中国战略有重要的意义。本研究以普通高校大学体育田径运动的教学及发展路径为切入点,对几所高校进行调查分析,找出田径运动发展过程中存在的问题,并提出相关建议,使田径运动在高校更好地发展,促进健康中国战略目标的贯彻实施。 相似文献
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利用UAS/hand-gal4系统构建果蝇心脏Nmnat基因特异性过表达,研究心脏Nmnat基因过表达联合耐力运动对高脂膳食诱发脂毒性心肌症的影响,并分析其分子机制。方法:雄性w^1118和NmnatUAS系果蝇分别与雌性hand-Gal4杂交,收集F1代心脏Nmnat正常表达(hand>w^1118)和过表达(hand>Nmnat)处女蝇,饲养至15 d后开始进行耐力运动(E)和高脂膳食(HFD),并分为hand>w^1118、hand>w^1118+E、hand>w^1118+HFD、hand>w^1118+HFD+E、hand>Nmnat、hand>Nmnat+E、hand>Nmnat+HFD、hand>Nmnat+HFD+E共8组,每组410只。ELISA检测心脏TAG、NAD+、SIR2蛋白去乙酰化、SOD活力和MDA水平,qRT-PCR检测心脏相关基因mRNA表达,M-mode检测心脏功能情况。结果:hand>w^1118+HFD+E果蝇心脏的Nmnat、dFoxo、bmm表达、NAD+水平、SIR2去乙酰化、SOD活力、缩短分数高于hand>w^1118+HFD(P<0.05或P<0.01),且d FAS和Col4al表达、TAG和MDA水平、心率和纤维性振颤低于hand>w^1118+HFD(P<0.05或P<0.01);hand>Nmnat果蝇心脏各指标与hand>Nmnat+HFD相比较未见显著差异(P>0.05);hand>Nmnat+HFD+E果蝇心脏的Nmnat、dFoxo、bmm表达、心脏NAD+水平、SIR2去乙酰化、SOD活力、心脏缩短分数高于hand>Nmnat+HFD(P<0.05或P<0.01),且dFAS和Col4al表达\TAG和MDA水平、心率和纤维性振颤低于hand>Nmnat+HFD(P<0.05或P<0.01)。结论:心脏Nmnat过表达和耐力运动均能抵抗果蝇高脂膳食诱发的心脏脂质过度堆积、氧化损伤、减弱心脏收缩能力和增加纤维性振颤,其分子机制与心脏Nmnat/NAD+/SIR2/dFoxo通路活性增强有关。心脏Nmnat基因过表达联合耐力运动能更好地降低脂毒性心肌症的发生概率,其机制与二者联合对心脏Nmnat/NAD+/SIR2/dFoxo通路活性上调的叠加作用有关。 相似文献
4.
In this paper, the optimal synchronization controller design problem for complex dynamical networks with unknown system internal dynamics is studied. A necessary and sufficient condition on the existence of the optimal control minimizing a quadratic performance index is given. The optimal control law consists of a feedback control and a compensated feedforward control, and the feedback control gain can be obtained by solving the well-known Algebraic Riccati Equation (ARE). Especially, in the presence of unknown system dynamics, a novel adaptive iterative algorithm using the information of system states and inputs is proposed to solve the ARE to get the optimal feedback control gain. Finally, a simulation example shows the effectiveness of the theoretical results. 相似文献
5.
In this paper, the synchronization problem of fractional-order neural networks (FNNs) with chaotic dynamics is investigated via the intermittent control strategy. Two types of intermittent control methods, the aperiodic one and the periodic one, are applied to achieve the synchronization of the considered systems. Based on the dynamic characteristics of the intermittent control systems, the piecewise Lyapunov function method is employed to derive the synchronization criteria with less conservatism. The results under the aperiodically intermittent control show more generality than the ones via the periodically intermittent control. For each of the aperiodic and periodic cases, a simple controller design process is presented to show how to design the corresponding intermittent controller. Finally, two numerical examples are provided to demonstrate the effectiveness of the obtained theoretical results. 相似文献
6.
目的:探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法:将雄性Wistar大鼠50只随机均分为5组:安静对照组(C)、低负荷运动训练组(LT)、中等负荷运动训练组(MT)、高负荷运动训练组(HT)和极高负荷运动训练组(ST),每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后,取腓肠肌样本,提取线粒体,测定线粒体柠檬酸合成酶(CS)、异柠檬酸脱氢酶(ICD)和α-酮戊二酸脱氢酶(α-KGDHC)活性;线粒体Ga2+含量、胞浆NADH、NAD+、ATP和ADP含量,以及ICD mRNA转录水平。结果:(1)不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组(P < 0.01),且CS和ICD活性由高到低顺序均为:MT组 > HT组 > ST组 > LT组 > C组,α-KGDHC活性由高到低顺序为:HT组 > MT组 > ST组 > LT组 > C组。(2)不同负荷运动训练组线粒体Ca2+ 含量均显著高于安静对照组(P < 0.01),其含量由高到低顺序为:MT组 > HT组 > ST组 > LT组 > C组;胞浆NADH/NAD+和ATP/ADP的比值均显著低于安静对照组(P < 0.01),其比值由低到高顺序为:MT组 < ST组 < HT组 < LT组 < C组。(3)不同负荷运动训练组ICD mRNA转录水平均高于安静对照组(P < 0.01),其水平由高到低顺序为: MT组 > HT组 > ST组 > LT组 > C组。结论:低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能,且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD+和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。 相似文献
7.
This paper focuses on the problem of semi-global output-feedback stabilization for a class of switched nonlinear time-delay systems in strict-feedback form. A switched state observer is first constructed, then switched linear output-feedback controllers for individual subsystems are designed. By skillfully constructing multiple Lyapunov–Krasovskii functionals and successfully solving several troublesome obstacles, such as time-varying delay and switching signals and nonlinearity in the design procedure, the switched linear output-feedback controllers designed can render the resulting closed-loop switched system semi-globally stabilizable under a class of switching signals with average dwell time. Furthermore, under some milder conditions on nonlinearities, the semi-global output-feedback stabilization problem for switched nonlinear time-delay systems is also studied. Simulation studies on two examples, which include a continuous stirred tank reactor, are carried out to demonstrate the effectiveness of the proposed approach. 相似文献
8.
This article presents a multi-lagged-input based data-driven adaptive iterative learning control (M-DDAILC) method for nonlinear multiple-input-multiple-output (MIMO) systems by virtue of multi-lagged-input iterative dynamic linearization (IDL). The original nonlinear and non-affine MIMO system is equivalently transformed into a linear input-output incremental counterpart without loss of dynamics. The proposed learning law utilizes the desired trajectory to cancel the influence from iteration-by-iteration variations, as well as additional multi-lagged inputs to improve control performance. The developed iterative estimation law is more effective and also makes estimation of the unknown parameters easier because the dynamics for each parameter to represent are decreased by dividing the system into multiple components in the multi-lagged-input IDL formulation. Moreover, the proposed M-DDAILC does not need an explicit and accurate model. It is proved to be iteratively convergent with rigorous analysis. Both a numerical example and a practical application to a permanent magnet linear motor are provided to verify the validity and applicability of the proposed method. 相似文献
9.
Qun Liu Daqing Jiang Tasawar Hayat Ahmed Alsaedi 《Journal of The Franklin Institute》2019,356(5):2960-2993
In this paper, we consider a stochastic multigroup SIQR epidemic model with standard incidence rates. By using the stochastic Lyapunov function method, we establish sufficient conditions for the existence of a stationary distribution of the positive solutions to the model. Then we establish sufficient conditions for extinction of the diseases. A stationary distribution means that all the individuals can be coexistent and persistent in the long term. Finally, some examples and numerical simulations are introduced to illustrate our theoretical results. 相似文献
10.
Yoann M. Garnier Christos Paizis Romuald Lepers 《European Journal of Sport Science》2019,19(2):166-176
The present study assessed neuromuscular and corticospinal changes during and after a fatiguing submaximal exercise of the knee extensors in different modes of muscle contraction. Twelve subjects performed two knee extensors exercises in a concentric or eccentric mode, at the same torque and with a similar total impulse. Exercises consisted of 10 sets of 10 repetitions at an intensity of 80% of the maximal voluntary isometric contraction torque (MVIC). MVIC, maximal voluntary activation level (VAL) and responses of electrically evoked contractions of the knee extensors were assessed before and after exercise. Motor evoked potential amplitude (MEP) and cortical silent period (CSP) of the vastus medialis (VM) and rectus femoris (RF) muscles were assessed before, during and after exercise. Similar reductions of the MVIC (?13%), VAL (?12%) and a decrease in the peak twitch (?12%) were observed after both exercises. For both VM and RF muscles, MEP amplitude remained unchanged during either concentric or eccentric exercises. No change of the MEP amplitude input–output curves was observed post-exercise. For the RF muscle, CSP increased during the concentric exercise and remained lengthened after this exercise. For the VM muscle, CSP was reduced after the eccentric exercise only. For a similar amount of total impulse, concentric and eccentric knee extensor contractions led to similar exercise-induced neuromuscular response changes. For the two muscles investigated, no modulation of corticospinal excitability was observed during or after either concentric or eccentric exercises. However, intracortical inhibition showed significant modulations during and after exercise. 相似文献