Ferulic acid prevents liver injury and increases the anti-tumor effect of diosbulbin B in vivo   总被引：1，自引：0，他引：1  

Jun-ming WANG  Yu-chen SHENG  Li-li JI  Zheng-tao WANG 《Journal of Zhejiang University. Science. B》2014,15(6):540-547

The present study is designed to investigate the protection by ferulic acid against the hepatotoxicity induced by diosbulbin B and its possible mechanism, and further observe whether ferulic acid augments diosbulbin B-induced anti-tumor activity. The results show that ferulic acid decreases diosbulbin B-increased serum alanine transaminase/aspartate transaminase (ALT/AST) levels. Ferulic acid also decreases lipid peroxide (LPO) levels which are elevated in diosbulbin B-treated mice. Histological evaluation of the liver demonstrates hydropic degeneration in diosbulbin B-treated mice, while ferulic acid reverses this injury. Moreover, the activities of copper- and zinc-containing superoxide dismutase (CuZn-SOD) and catalase (CAT) are decreased in the livers of diosbulbin B-treated mice, while ferulic acid reverses these decreases. Further results demonstrate that the mRNA expressions of CuZn-SOD and CAT in diosbulbin B-treated mouse liver are significantly decreased, while ferulic acid prevents this decrease. In addition, ferulic acid also augments diosbulbin B-induced tumor growth inhibition compared with diosbulbin B alone. Taken together, the present study shows that ferulic acid prevents diosbulbin B-induced liver injury via ameliorating diosbulbin B-induced liver oxidative stress injury and augments diosbulbin B-induced anti-tumor activity.  相似文献   

基于XML的外贸企业B2E电子商务与知识共享系统     

杨宝森  刘鲁  来玲 《情报杂志》2006,25(7):12-15

通过将B2E电子商务理念与XML软件技术结合构建了外贸企业个性化协同工作的电子商务和知识共享系统。它超越了传统的Web门户网站的概念,建立了一个跨组织、跨部门,以外贸供应链结点为对象的交互工作平台。通过商业语义转换,以XML方式将业务系统形成的单证信息以及数据流提交给其他系统,构造了外贸企业与相关企业间的电子商务网关。  相似文献   

中国兰科植物一新种——云南巾唇兰     

陈心启  罗毅波 《中国科学院研究生院学报》2004,42(5):457-459

对中国兰科植物新种云南巾唇兰Pennilabium yunnanense S.C.Chen&Y.B.Luo作了 描述和绘图。该新种与P.acuminatum（Ridley）Holttum较为接近，区别点在于具较小的花朵 ，直径仅3cm;花瓣白色且上面有深紫色斑点，以及唇瓣侧裂片顶端有流苏。  相似文献   

从"雅蜂模式"谈B2B网站联盟     

刘红梅 《科教文汇》2007,(7)

在今年刚结束的首届"中国B2B联盟大会暨高峰论坛"上,中国首家全英文的国际贸易B2B垂直搜索引擎Yaphon雅蜂网正式宣告"雅蜂B2B网站联盟"成立,本文基于"雅蜂模式"探讨了B2B网站的联盟策略.  相似文献   

Periodic solutions for third order p-Laplacian equation with a deviating argument     

Shan Jin  Shiping Lu 《Journal of The Franklin Institute》2009,346(2):126-135

By means of Mawhin's continuation theorem, we study a third-order p-Laplacian differential equation