Directed collaboration patterns in funded teams: A perspective of knowledge flow     

《Information processing & management》2023,60(2):103237

Collaborations in funded teams are essential for understanding funded research and funding policies, although of high interest, are still not fully understood. This study aims to investigate directed collaboration patterns from the perspective of the knowledge flow, which is measured based on the academic age. To this end, we proposed a project-based team identification approach, which gives particular attention to funded teams. The method is applicable to other funding systems. Based on identified scientific teams, we detected recurring and significant subgraph patterns, known as network motifs, and under-represented patterns, known as anti-motifs. We found commonly occurred motifs and anti-motifs are remarkably characterized by different structures matching certain functions in knowledge exchanges. Collaboration patterns represented by motifs favor hierarchical structures, supporting intensive interactions across academic generations. Anti-motifs are more likely to show chain-like structures, hindering potentially various knowledge activities, and are thus seldom found in real collaboration networks. These findings provide new insights into the understanding of funded collaborations and also the funding system. Meanwhile, our findings are helpful for researchers, the public and policymakers to gain knowledge on research(ers) evolution, particularly in terms of primordial collaboration patterns.  相似文献   

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

Paternal support for child sexual abuse victims: A qualitative study     

《Child abuse & neglect》2019

BackgroundThe current state of knowledge regarding the role of non-offending fathers in supporting their sexually abused children is very scarce.ObjectiveThe objective of this study is to further our understanding of fathers’ roles following disclosure of their children’s sexual abuse (SA) by evaluating fathers’ perceptions of the impact of disclosure on their involvement and support of their children.Participants and methodThis qualitative study relies on individual semi-structured interviews conducted with 17 fathers of allegedly abused children.ResultsInductive thematic analysis first highlighted that some reported a period of disengagement from the child during which they put into question their role and attitudes, followed by a period of re-involvement. This period of difficulties experienced by some fathers in regard to their involvement towards their children was due to either their own important psychological distress, their ambivalence towards their child or even because of feelings of uneasiness experienced during physical contact with them. Despite this, findings indicate the presence of thoughts and attitudes that suggest children are a source of concern for fathers. The four forms of abuse-specific support previously observed among mothers (believing the child, seeking out professional services, protecting him/her from the offender, supporting him/her emotionally) were also observed among fathers. In accordance with the activation theory, a form of support specific to fathers, namely, encouraging the child to open up to and explore the world outside the family, thereby, fostering the child’s self-esteem development, was observed and constitutes a relevant finding.ConclusionClinical and empirical implications are discussed.  相似文献   

欧洲九国共产党情报局机关刊物《争取持久和平,争取人民民主!》与中国关系考述(1949-1956)     

哈战荣 《图书馆杂志》2020,(4):21-26

《争取持久和平,争取人民民主!》是20世纪40年代中后期,欧洲九个社会主义国家的共产党和工人党为了一致行动而建立的情报局机关刊物。该刊物对新中国初期我国经济社会建设及成就进行了大量宣传与报道,对加强我国与世界其他爱好和平、渴求民主的各国人民加强互信、长存友谊贡献很大,也对当前学者研究新中国初期我国经济社会发展的过程、成就和经验等提供了原始史料,学术研究意义也很重大。但是,目前对这份刊物及其发挥过的重大作用了解的人少之又少,时值中国共产党成立100周年之际,对其创刊与发行的历史过程进行回顾、宣传中国社会经济发展的全貌进行展示、推动世界社会主义运动的作用进行肯定,意义都很重大。  相似文献   

“流空间”视角下粤港澳大湾区空间布局分级特征研究   总被引：1，自引：0，他引：1  

杨思蓓  胡志华 《上海海事大学学报》2020,41(1):93-99

为加快粤港澳大湾区区域一体化进程,基于“流空间”视角,以粤港澳大湾区11个核心城市为研究对象,从客运流、经济流、信息流三个维度建立数理统计模型,分析粤港澳大湾区的交通、物流和经济信息化水平,并综合运用Jenks自然断裂点法和Moran散点图对粤港澳大湾区进行空间布局分级特征研究。研究结果表明:粤港澳大湾区有两个增长极——广州和深圳;粤港澳大湾区以珠江为界,珠江东西两岸分级明显;港珠澳大桥的连通有助于加强流要素空间互动,发挥更强的区域辐射和带动作用,扩大H-H连绵区的分布范围。  相似文献   

试论《明人十二像册》高度写真风格的中国渊源     

黄乐乐 《美育学刊》2020,11(2):116-120

现藏于南京博物院的一批无款写真头像《明人十二像册》,是中国写实画的一座高峰。对于这个像册的绘画风格,现当代学者多半都偏向认为是受到西方绘画的影响。但经与西方圣像画比较研究,像册仍属于中国本土的绘画传统,受到了宋代山水画和花鸟画高度写真精神的影响。  相似文献   

液滴撞击凹凸槽道表面液膜的动态演变     

周鑫  王宏  朱恂  陈蓉  廖强  丁玉栋 《中国科学院大学学报》2020,37(2):255-262

为研究固体表面结构对液滴撞击液膜后演变行为的影响规律，采用CLSVOF方法模拟液滴撞击不同尺寸槽道上的表面液膜的流动过程，获得不同槽道高度和宽度时液滴撞击液膜后的演变行为，探索撞击速度、液膜黏度和表面张力对撞击后液膜铺展行为、水花飞溅高度和二次液滴形成的影响。结果表明，槽道结构对液滴撞击液膜后的动态行为具有显著影响，随着槽道高度的增加，冠状水花厚度越薄，越容易产生二次液滴；随着液膜黏度的增大，则抑制冠状水花形成与二次液滴的产生；液膜表面张力减小时，射流更加明显，二次液滴数更多，飞溅现象提前，冠状水花消失时间延后。  相似文献   

低负荷加压训练改善自发性高血压大鼠的血压效果及机制研究     

谭朝文  赵彦  俞莹莹  马晓缓  郑玉婵 《体育科学》2020,(3):46-53,63

目的:探究低负荷加压训练对自发性高血压大鼠的降压效果及其作用机制。方法:选取4周龄雄性自发性高血压大鼠,随机分为对照组(高血压安静组)、低负荷训练组、低负荷加压训练组和高负荷训练组。低负荷训练组进行35%~55%1RM递进式低负荷爬梯训练,低负荷加压训练组进行30%~40%血流受限结合35%~55%1RM递进式低负荷爬梯训练,高负荷训练组进行55%~75%1RM递进式高负荷爬梯训练,训练后测定血压、血液中内皮素-1、血管内皮生长因子、一氧化氮合成酶的表达和心肌组织中内皮型一氧化氮合成酶的表达。结果:1)与对照组、高负荷训练组相比,低负荷加压训练组收缩压、舒张压显著下降(P<0.05);与低负荷训练组相比,低负荷加压训练组舒张压显著下降(P<0.05)。2)与对照组相比,低负荷加压训练组血液中内皮素-1表达显著下调(P<0.05),血管内皮生长因子和一氧化氮合成酶表达显著上调(P<0.05);3)与对照组相比,低负荷加压训练组心肌中内皮型一氧化氮合成酶表达显著上调(P<0.05);4)在低负荷加压训练组中,收缩压与内皮素-1呈正相关,相关性分析具有统计学意义(P<0.05);收缩压与一氧化氮合成酶、血管内皮生长因子、内皮型一氧化氮合成酶均呈负相关,相关性分析具有统计学意义(P<0.05)。结论:1)低负荷加压训练降压效果优于高负荷训练;2)低负荷加压训练能够通过下调血液中内皮素-1的表达,上调血液中血管内皮生长因子和一氧化氮合成酶的表达,同时上调心肌中内皮型一氧化氮合成酶表达,改善内皮细胞功能,达到降压的效果。  相似文献   

坦桑尼亚县域与城乡交通通达水平空间格局特征     

张家旗  陈爽  高群  ISMAEL A. Kimirei 《中国科学院大学学报》2019,36(6):766-773

坦桑尼亚是"一带一路"倡议通向非洲、辐射非洲内陆的重要门户，它在快速城市化过程中面临交通基础设施严重短缺问题。基于坦桑尼亚公路、铁路、机场、港口、人口和城市分布数据，运用GIS空间分析技术，结合交通通达指数模型，从县域与城乡两个层面对坦桑尼亚交通通达水平的空间格局特征进行定量分析。研究发现：1）坦桑尼亚县域交通通达水平空间分布极不均衡，高值连片区主要位于东北沿海和维多利亚湖沿岸，低值连片区主要位于中央铁路线中段以北、中央铁路线南部的广大地区；2）受地理区位、资源禀赋、殖民历史、政府政策等影响，城市与乡村地区之间的交通通达水平差异十分显著。研究结果有助于坦桑尼亚制定区域交通发展政策和优化资源配置，同时对中-坦产业精准对接和产能转移具有一定的促进意义。  相似文献   

Combined effects of exposure to hypoxia and cool on walking economy and muscle oxygenation profiles at tibialis anterior     

Masahiro Horiuchi  Yoko Handa-Kirihara  Daijiro Abe  Yoshiyuki Fukuoka 《Journal of sports sciences》2019,37(14):1638-1647

We investigated combined effects of ambient temperature (23°C or 13°C) and fraction of inspired oxygen (21%O₂ or 13%O₂) on energy cost of walking (C_w: J·kg^?1·km^?1) and economical speed (ES). Eighteen healthy young adults (11 males, seven females) walked at seven speeds from 0.67 to 1.67 m s^?1 (four min per stage). Environmental conditions were set; thermoneutral (N: 23°C) with normoxia (N: 21%O₂) = NN; 23°C (N) with hypoxia (H: 13%O₂) = NH; cool (C: 13°C) with 21%O₂ (N) = CN, and 13°C (C) with 13%O₂ (H) = CH. Muscle deoxygenation (HHb) and tissue O₂ saturation (StO₂) were measured at tibialis anterior. We found a significantly slower ES in NH (1.289 ± 0.091 m s^?1) and CH (1.275 ± 0.099 m s^?1) than in NN (1.334 ± 0.112 m s^?1) and CN (1.332 ± 0.104 m s^?1). Changes in HHb and StO₂ were related to the ES. These results suggested that the combined effects (exposure to hypoxia and cool) is nearly equal to exposure to hypoxia and cool individually. Specifically, acute moderate hypoxia slowed the ES by approx. 4%, but acute cool environment did not affect the ES. Further, HHb and StO₂ may partly account for an individual ES.  相似文献