不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制研究     

李洁  杨静  赵丽丽 《武汉体育学院学报》2019,53(5):88-94

目的：探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法：将雄性Wistar大鼠50只随机均分为5组：安静对照组（C）、低负荷运动训练组（LT）、中等负荷运动训练组（MT）、高负荷运动训练组（HT）和极高负荷运动训练组（ST），每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后，取腓肠肌样本，提取线粒体，测定线粒体柠檬酸合成酶（CS）、异柠檬酸脱氢酶（ICD）和α-酮戊二酸脱氢酶（α-KGDHC）活性；线粒体Ga²⁺含量、胞浆NADH、NAD⁺、ATP和ADP含量，以及ICD mRNA转录水平。结果：（1）不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组（P < 0.01），且CS和ICD活性由高到低顺序均为：MT组 > HT组 > ST组 > LT组 > C组，α-KGDHC活性由高到低顺序为：HT组 > MT组 > ST组 > LT组 > C组。（2）不同负荷运动训练组线粒体Ca²⁺ 含量均显著高于安静对照组（P < 0.01），其含量由高到低顺序为：MT组 > HT组 > ST组 > LT组 > C组；胞浆NADH/NAD⁺和ATP/ADP的比值均显著低于安静对照组（P < 0.01），其比值由低到高顺序为：MT组 < ST组 < HT组 < LT组 < C组。（3）不同负荷运动训练组ICD mRNA转录水平均高于安静对照组（P < 0.01），其水平由高到低顺序为： MT组 > HT组 > ST组 > LT组 > C组。结论：低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能，且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD⁺和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。  相似文献   

Facial feature tracking: a psychophysiological measure to assess exercise intensity?     

Kathleen H. Miles  Bradley Clark  Julien D. Périard  Roland Goecke  Kevin G. Thompson 《Journal of sports sciences》2018,36(8):934-941

The primary aim of this study was to determine whether facial feature tracking reliably measures changes in facial movement across varying exercise intensities. Fifteen cyclists completed three, incremental intensity, cycling trials to exhaustion while their faces were recorded with video cameras. Facial feature tracking was found to be a moderately reliable measure of facial movement during incremental intensity cycling (intra-class correlation coefficient = 0.65–0.68). Facial movement (whole face (WF), upper face (UF), lower face (LF) and head movement (HM)) increased with exercise intensity, from lactate threshold one (LT1) until attainment of maximal aerobic power (MAP) (WF 3464 ± 3364mm, P < 0.005; UF 1961 ± 1779mm, P = 0.002; LF 1608 ± 1404mm, P = 0.002; HM 849 ± 642mm, P < 0.001). UF movement was greater than LF movement at all exercise intensities (UF minus LF at: LT1, 1048 ± 383mm; LT2, 1208 ± 611mm; MAP, 1401 ± 712mm; P < 0.001). Significant medium to large non-linear relationships were found between facial movement and power output (r² = 0.24–0.31), HR (r² = 0.26–0.33), [La^?] (r² = 0.33–0.44) and RPE (r² = 0.38–0.45). The findings demonstrate the potential utility of facial feature tracking as a non-invasive, psychophysiological measure to potentially assess exercise intensity.  相似文献   

论学生表达自由的内涵及其表现形式     

茅锐  范文 《比较教育研究》2007,28(8):39-43

作为一种基础性的宪法权利,学生享有表达自由权.本文首先探讨了表达自由权的概念及其必要性.其次,本文认为学生的表达自由具有多种形式,主要包括言论自由、发型自由、着装自由、集会及结社自由.最后,本文强调指出,学校管理者应尊重并保护学生的表达自由,促进学生权利与学校管理权力的和谐发展.  相似文献   

浅论书法线条的艺术魅力     

张长林 《商洛学院学报》2004,18(3):60-62

将线条从书法艺术完整的形态中提取出来,通过对线的象形性、意象性、时空性、运动性以及表情性几个方面的分析,由外在视觉到内在心理感受书法线条作为艺术表现语言的魅力所在。  相似文献   

语用失误与语用能力的培养     

梁改萍 《安徽教育学院学报》2004,22(2):86-87

大学英语教学应注重文化差异的介绍和语用的输入,要及时发现语用失误,纠正语用失误,培养学生的语用能力.  相似文献   

A Simple Model to Determine the Efficient Duration of Exams     

Jules L. Ellis 《Educational and psychological measurement》2021,81(3):549

This study develops a theoretical model for the costs of an exam as a function of its duration. Two kind of costs are distinguished: (1) the costs of measurement errors and (2) the costs of the measurement. Both costs are expressed in time of the student. Based on a classical test theory model, enriched with assumptions on the context, the costs of the exam can be expressed as a function of various parameters, including the duration of the exam. It is shown that these costs can be minimized in time. Applied in a real example with reliability .80, the outcome is that the optimal exam time would be much shorter and would have reliability .675. The consequences of the model are investigated and discussed. One of the consequences is that optimal exam duration depends on the study load of the course, all other things being equal. It is argued that it is worthwhile to investigate empirically how much time students spend on preparing for resits. Six variants of the model are distinguished, which differ in their weights of the errors and in the way grades affect how much time students study for the resit.  相似文献   

在初中语文教学中注重学生综合能力的培养     

范中军 《天津教育》2021,(5):60-61,64

现实生活中,有的人出口成章,妙语连珠,能随口说出文学作品中的经典语;有的人运用谐音、双关的修辞语言,让人回味无穷;有的人说出来的话语通俗易懂……真正的语言艺术是社会历史发展的产物,也是劳动人民智慧的结晶。因此,培养学生的语言表达能力,是语文教学最根本的使命。  相似文献   

诵读在英语教学中的应用探索     

赵秀花 《成才之路》2021,(15):136-137

英语是一门语言学科,诵读对于提高学生英语学习能力具有重要的促进作用,可以提高学生英语听力,提高学生语感和口语水平,提高学生写作能力。在英语教学过程中,教师要注重学生的英语发音,激发学生英语学习兴趣,模拟英语交流情境,提高学生英语表达能力,提升学生英语学科素养。  相似文献   

立足绘本阅读 提升儿童语言表达能力     

陈桂花 《成才之路》2021,(14):70-71

绘本是儿童的重要阅读材料,有助于儿童阅读习惯的培养,有利于儿童语言表达能力的提高。学校及教师应该重视绘本阅读,立足于培养学生语言表达能力的目标,根据学生的年龄特点和认知规律选择合适的主题绘本,还要根据绘本特点对学生进行针对性的指导,并通过展示和评价活动保证绘本阅读的效果。  相似文献   

Genome-wide analysis of microRNA156 and its targets,the genes encoding SQUAMOSA promoter-binding protein-like (SPL) transcription factors,in the grass family Poaceae     

Yue  Erkui  Tao  Hua  Xu  Jianhong 《Journal of Zhejiang University. Science. B》2021,22(5):366-382

  相似文献