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赵军强 《数学学习与研究(教研版)》2014,(22):2
《数学课程标准》中这样描述:"中学数学教育要努力培养学生积极探索知识、建构知识,通过他们自主的、积极的尝试获取知识,教师灌输式教学的传统要予以改变,这样有利于学生经历知识形成的过程、获取知识的深刻度大大加深、知识记忆的程度也远远大于被动接受."十多年前开始的新一轮课程初始,课程标准提出了上述的教学改变和教学理念,时至今日,我们回头看看实际情况如何呢?我们又该如何进一步去实施学生积极课堂参与呢?本文将从成因、现状等角 相似文献
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In recent years, organic-inorganic hybrid nanocarriers are explored for effective drug delivery and preferable disease treatments. In this study, using 5-fluorouracil(5-FU)as electronegative model drug, a new type of organic-inorganic hybrid drug delivery system(LDH/HA-PEG/5-FU)was conceived and manufactured by the adsorption of PEGylated hyaluronic acid(HA-PEG)on the surface of layered double hydroxide(LDH, prepared via hydrothermal method)and the intercalation of 5-FU in the interlamination of LDH via ion exchange strategy. The drug loading amount of LDH/HA-PEG/5-FU achieved as high as 34.2%. LDH, LDH/5-FU and LDH/HA-PEG/5- FU were characterized by FT-IR, XRD, TGA, laser particle size analyzer and SEM. With the benefit of pHdegradable feature of LDH and enzyme-degradable feature of HA, LDH/HA-PEG/5-FU showed pH-degradable and enzyme-degradable capacity in in vitro drug release. Moreover, the drug carrier LDH/HA-PEG contained biocompatible PEG and tumor-targeted HA, resulting in lower cytotoxicity and better endocytosis compared with LDH in vitro. It was suggested that the organic-inorganic hybrid drug delivery system, which was endowed with the properties of controlled release, low toxicity and tumor-targeting delivery for ameliorative cancer therapy, was advisable and might be applied further to fulfill other treatments. 相似文献
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文章从中职教育高素质技能型人才培养要求出发,结合地方企业岗位技能要求,根据学校教学实际,总结了在数控加工实训教学的教材、教学方法、学生考核评价等方面的改革。 相似文献
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