Factors influencing the outcome of embryo freezing and thawing program     

叶英辉  金帆  徐晨明  邢兰凤 《浙江大学学报(A卷英文版)》2002,3(4):493-496

Objective: To investigate the factors that might influence the success of an embryo freezing and thawing program. Method: The relationship between the pregnancy rate in 73 cycles of embryo, freezing and thawing program and the following factors was analyzed: maternal age,E ₂ level at the time of HCG trigger, embryo storage time, number of thawed embryos transferred, presence of sponsoring embryos and intact embryos. And the survival rate of thawed embryos with different morphology, cell stage and storage time was evaluated. Result: Transfer with three or more than three thawed embryos resulted in pregnancy rates of 38.5% and 35.7%, respectively, compared with 5.3% for transfer of fewer than three embryos. The presence of sponsoring embryos and intact embryos significantly increases pregnancy rate in embryo freezing and thawing program. No other factor examined had any effect on pregnancy outcome. The survival rate of good morphology embryos was higher than poor ones, but was not influenced by cell stage and storage time. Conclusion: Embryo morphology before freezing, number of thawed embryos transferred and the presence of intact embryos are important to the outcome of embryo freezing and thawing program.  相似文献   

冻存胚胎复苏移植的影响因素   总被引：4，自引：0，他引：4  

叶英辉  金帆  邢兰凤  徐晨明 《科技通报》2001,17(1):67-71,74

为探讨冻存胚胎复苏移植妊娠的影响因素，统计分析了28个周期127个冻存胚胎复苏移植的妊娠率与胚胎冻存前形态，细胞数，保存时间，复苏后存活率，培养至次日的继续分裂率等因素的关系，表明妊娠周期冻存前胚胎形态良好比较，复苏后存活率，复苏后培养至次日继续分裂的比例有增高的趋势，胚胎细胞数妊娠与非妊娠周期相似，形态良好胚胎复苏后存活率显著高于形态不良者，说明冻存前胚胎形态与胚胎复苏存活率和冻存胚胎复苏移植妊娠率关系重要。  相似文献