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1.
ABSTRACT

We performed a randomized, controlled trial to analyse the effects of resistance training (RT) on cognitive and physical function among older adults. Fifty participants (mean age 67 years, ~60% woman) were randomly assigned to an RT program or a control group. Participants allocated to RT performed three sets of 10-15RM in nine exercises, three times per week, for 12-weeks. Control group did not perform any exercise. Variables included cognitive (global and executive function) and physical function (gait, mobility and strength) outcomes. At completion of the intervention, RT was shown to have significantly mitigated the drop in selective attention and conflict resolution performance (Stroop test: -494.6; 95%CI: -883.1; ?106.1) and promoted a significant improvement in working memory (digit span forward: -0.6; 95%CI: ?1.0; ?0.1 and forward minus backward: -0.9; 95% CI: ?1.6; ?0.2) and verbal fluency (animal naming: +1.4, 95%CI 0.3, 2.5). No significant between-group differences were observed for other cognitive outcomes. Regarding physical function, at completion of the intervention, the RT group demonstrated improved fast-pace gait performance (?0.3; 95% CI: ?0.6; ?0.0) and 1-RM (+21.4 kg; 95%CI: 16.6; 26.2). No significant between-group differences were observed for other mobility-related outcomes. In conclusion, RT improves cognitive and physical function of older adults.  相似文献   
2.
Summary The case of a left-handed female patient is described who presented serious problems in learning how to write during childhood, particularly in relation to directionality and letter sequence. The patient then learned to write correctly with her left hand, but practiced and maintained her ability to write backwards (from the last letter to the first). Implications of the case are discussed.Send Correspondence to Dr. Alfredo Ardila, Miami Institute of Psychology of the Caribbean Center for Advanced Studies, 8180 NW 36 Street, Second floor, Miami, Florida 33166-6612.  相似文献   
3.
The aims of this study were to examine the changes in plasma concentrations of inflammatory cytokines induced by training and competition in professional cyclists. We report the serum concentrations of interleukin-6 (IL-6), tumour necrosis factor alpha (TNF-a), tumour necrosis factor receptors I and II (TNFR-I and -II) in a prospective, randomized, double-blind trial involving the administration of AM3 (Inmunoferon), an oral booster immunomodulator, or placebo to 16 professional cyclists (n = 8 in each group) for 65 consecutive days. Serum was collected just before treatment began (baseline), at the end of pre-competition training, before the mountain stage of the competition (60 days), 4 h after finishing this stage (62 days), and 18 h after the fifth and last day of competition (65 days). To determine the normal levels of cytokines and soluble TNF receptors, individual samples from 14 moderately trained healthy controls were studied. After 60 days of training, the serum concentrations of IL-6 did not differ significantly from those at the beginning of the study for either group of cyclists (placebo and AM3). A significant rise was seen in IL-6 concentrations in both the AM3 and placebo groups at 62 days, 4 h after finishing the mountain stage. The increase was significantly greater in the placebo group than in the AM3 group. At 65 days of treatment, 18 h after the fifth and last day of competition, IL-6 concentrations were similar to those recorded at the end of the training, but were significantly higher in the placebo group than in the AM3 group. At the end of training, serum TNFR-I concentrations in both groups of cyclists were significantly lower than at baseline. The concentrations of serum TNFR-I and -II both 4 h after finishing the mountain stage and 18 h after the fifth and last day of competition were significantly higher than those recorded after training in both groups. Professional cycling competition is associated with increases in serum IL-6 and TNFR-I and -II concentrations. Inmunoferon treatment reduced significantly the concentrations of IL-6 but not those of TNFR-I and -II.  相似文献   
4.
This paper explores how factors operating at the state and community levels are associated with the prevalence of late school enrolment in Nigeria. We investigate the following three research themes. First, whether late entry varies across states and across communities and how much of this variation can be explained by the composition of communities and states. Second, whether community wealth and state wealth are stronger predictors of late entry than household wealth. Third, whether wealth has different effects on the probability of late school entry in different states and in different communities within states. Using the 2010 Nigeria Education Data Survey, and a three-level multilevel logit model, we show that a substantial proportion of the variation in late school entry is explained by community- and state-level factors. We further find that children living in specific communities in Nigeria may face a double disadvantage in terms of on-time school enrolment. In these communities, not only is there a large proportion of children entering school late, but also household wealth has strong effects on the probability that a child is sent to school on on time. These communities could be targeted for educational interventions aimed at promoting on-time school enrolment.  相似文献   
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6.
Digital libraries of scientific articles contain collections of digital objects that are usually described by bibliographic metadata records. These records can be acquired from different sources and be represented using several metadata standards. These metadata standards may be heterogeneous in both, content and structure. All of this implies that many records may be duplicated in the repository, thus affecting the quality of services, such as searching and browsing. In this article we present an approach that identifies duplicated bibliographic metadata records in an efficient and effective way. We propose similarity functions especially designed for the digital library domain and experimentally evaluate them. Our results show that the proposed functions improve the quality of metadata deduplication up to 188% compared to four different baselines. We also show that our approach achieves statistical equivalent results when compared to a state-of-the-art method for replica identification based on genetic programming, without the burden and cost of any training process.  相似文献   
7.
Abstract High physical fitness in childhood and adolescence is positively associated with favourable health-related outcomes. Our aim was to examine the relationship between relatives' (father, mother, brother, sister, and best friend) physical activity engagement and encouragement on adolescents' physical fitness. Adolescents were part of the HELENA study, a multi-centre study conducted in 10 cities from nine European countries in 2006-2008. Participants were 3288 adolescents (48% boys, 52% girls) aged 12.5-17.5 years with valid data on at least one of the three fitness variables studied: muscular strength (standing long jump), speed/agility (4×10 m shuttle run), and cardiorespiratory fitness (20 m shuttle run). The adolescents reported their relatives' physical activity engagement and encouragement. Analysis of covariance showed that relatives' physical activity engagement (father, mother, brother, and best friend) was positively related to cardiorespiratory fitness (P?相似文献   
8.
This paper proposes a new sliding mode observer for fault reconstruction, applicable for a class of linear parameter varying (LPV) systems. Observer schemes for actuator and sensor fault reconstruction are presented. For the actuator fault reconstruction scheme, a virtual system comprising the system matrix and a fixed input distribution matrix is used for the design of the observer. The fixed input distribution matrix is instrumental in simplifying the synthesis procedure to create the observer gains to ensure a stable closed-loop reduced order sliding motion. The ‘output error injection signals’ from the observer are used as the basis for reconstructing the fault signals. For the sensor fault observer design, augmenting the LPV system with a filtered version of the faulty measurements allows the sensor fault reconstruction problem to be posed as an actuator fault reconstruction scenario. Simulation tests based on a high-fidelity nonlinear model of a transport aircraft have been used to demonstrate the proposed actuator and sensor FDI schemes. The simulation results show their efficacy.  相似文献   
9.
We review empirical research on English language learners (ELLs) who struggle with reading and who may have learning disabilities (LD). We sought to determine research indicators that can help us better differentiate between ELLs who struggle to acquire literacy because of their limited proficiency in English and ELLs who have actual LD. We conclude that more research is warranted to further elucidate the strengths and learning needs of subgroups of underachieving ELLs, to help us determine who should qualify for special education, and to clarify why some ELLs who do not have LD still struggle with language and literacy acquisition. Future research should account for the complexities involved in becoming literate in another language and focus more on cultural and contextual factors that affect student achievement.  相似文献   
10.
Teachers' written reflections on their work, which report on a change in their practice, were the object of this research. Taking teachers' articulation of their plans and actions in teacher journals as our source, this study's aim is twofold: (1) to describe how teacher reflect in a self‐initiated and non‐framed way on their own practice, and (2) to review teacher self generated reflections in reference to models of reflection. In this way, we tried to disclose what precisely teachers write (said) when reflecting on their work (did) in order to appreciate their way of describing what matters in their work; and position this in reference to models that conceptualise (“talk”) on how to actualise (‘walk’) reflection. This ‘double’ articulation of reflection is gauged in two ways, i.e., on: a) completeness, that is, whether it includes relevant components of reflection (models) to be found in the literature, and on b) recursiveness, that is, whether the written account gives evidence of an integrated cyclical, i.e., recursive process of re‐view, which appraises and looks back on what has been accomplished.

The results show that teachers do not work along the lines identified in current reflection models (i.e. providing clear problem definition, searching for evidence, planning for change, and reviewing plans). Instead, many teachers use a narrative and valuing appraisal of their accomplishments; not so much cautiously reviewing their actions but prospectively commenting on plans and solutions for future action. The data lead us to be cautious about the prominence of reflection models as advocated in the literature to be applied to teachers' written accounts of their practice.  相似文献   
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