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ABSTRACT: An evaluation of interactive video conferencing and Web-assisted instruction to deliver a multidisciplinary course entitled Phytochemicals in Fruits and Vegetables to Improve Human Health was conducted during the spring semesters of 1999 and 2001. This course was taught by 20 instructors from 11 institutions to 49 students during spring 2001, which was an increase of 53% over spring 1999. Weekly 3-h lectures were delivered by the Trans-Texas Videoconference Network integrated with PowerPoint® or HTML slides available on the course Web site ( http://phytochemicals.tamu.edu ). Qualitative and quantitative data were collected through formative and summative methods. Participants expressed their satisfaction with course format and the need for technical support for interactive videoconferencing.  相似文献   
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Although researchers have long investigated ways to improve study habits and raise achievement, few studies compare study strategy systems with one another. No study to date has compared the long popular SQ3R (Survey, Question, Read, Recite, Review) system with the more modern SOAR (Select, Organize, Associate, Regulate) system. This study directly compared SQ3R and SOAR to determine which is most effective. College students trained in the SQ3R or SOAR system and given corresponding study materials used their respective method to study a text in preparation for a test assessing fact, relationship, and concept learning. Results confirmed that students who used the SOAR system outperformed those who used the SQ3R system and learned 20 % more relationships, 14 % more facts, and 13 % more concepts. Results were attributed to SOAR’s cognitive processing advantages over SQ3R.  相似文献   
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Objective

The aim of this study was to formulate polymer-based artesunate nanoparticles for malaria treatment.

Methods

Artesunate was loaded with poly(D,L-lactic-co-glycolic acid) (PLGA) by solvent evaporation from an oil-in-water single emulsion. Nanoparticles were characterized by X-ray diffraction and differential scanning calorimetry analyses. In vivo antimalarial studies at 4 mg/kg were performed on Swiss male albino mice infected with Plasmodium berghei. Hematological and hepatic toxicity assays were performed. In vitro cytotoxicity of free and encapsulated artesunate (Art-PLGA) to cell line RAW 264.7 was determined at concentrations of 7.8–1000 μg/ml.

Results

The particle size of the formulated drug was (329.3±21.7) nm and the entrapment efficiency was (38.4±10.1)%. Art-PLGA nanoparticles showed higher parasite suppression (62.6%) compared to free artesunate (58.2%, P<0.05). Platelet counts were significantly higher in controls (305 000.00±148 492.40) than in mice treated with free artesunate (139 500.00±20 506.10) or Art-PLGA (163 500.00±3535.53) (P<0.05). There was no sign of hepatic toxicity following use of the tested drugs. The half maximal inhibitory concentration (IC50) of Art-PLGA (468.0 μg/ml) was significantly higher (P<0.05) than that of free artesunate (7.3 μg/ml) in the in vitro cytotoxicity assay.

Conclusions

A simple treatment of PLGA-entrapped artesunate nanoparticles with dual advantages of low toxicity and better antiplasmodial efficacy has been developed.
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This study investigated how best to study a matrix. Fifty-three participants studied a matrix topically (1 column at a time), categorically (1 row at a time), or in a unified way (all at once). Results revealed that categorical and unified study produced higher: (a) performance on relationship and fact tests, (b) study material satisfaction, and (c) associative strategy use than topical study. A supplemental study examined the benefits of adding signals to the unified matrix. Results showed that signaling produced greater use of global associative strategies and greater learning of global relationships. Findings were explained with respect to cognitive load theory. Implications for studying matrices were as follows: (1) do not just study a matrix topically, (2) study a matrix categorically, and (3) study a matrix in a unified way, but do so in a way that fosters comparative associations across multiple topics and categories.  相似文献   
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