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Wojciech Szczęsny Magdalena Kuligowska-Prusińska Stanisław Dąbrowiecki Jakub Szmytkowski Adrian Reśliński Maciej Słupski 《Journal of Zhejiang University. Science. B》2018,19(1):65-70
Purpose
Metalloproteinases are a key component of the pathogenesis of abdominal hernias. Obesity is considered a risk factor in herniogenesis and hernia recurrence. The aim of this study was to evaluate the serum concentrations of metalloproteinase-2 (MMP-2), MMP-9, MMP-13, and adiponectin in morbidly obese and nonoverweight controls.Materials and methods
The participants were recruited from among patients undergoing bariatric and non-bariatric surgery and divided into two groups: I (body mass index (BMI)≥35 kg/m2, n=40) and II (BMI<25 kg/m2, n=30). Serum concentrations of MMP-2, MMP-9, MMP-13, and adiponectin were measured using enzyme-linked immunosorbent assay (ELISA).Results
A statistically significant difference between groups was observed for MMP-2 concentration. The median MMP-9 concentration was higher in the obese group, but the difference was not statistically significant. Median MMP-13 concentrations did not differ between groups. Serum adiponectin concentration was insignificantly higher in the non-obese group.Conclusions
The elevated serum MMP-2 and MMP-9 concentrations in obese individuals may be related to the higher incidence of incisional hernias in this population.2.
Marcin Krasnodębski 《Minerva》2018,56(3):333-355
The initiatives attempting to forge links between the academia and the industry flourished in France after World War I. The so-called “industrial institutes” shared a common goal: to reinvigorate the French economy through science. Because of their focus on applied research, they differed from traditional engineering schools that usually neglected laboratory work and innovation. However, while the industrial institutes were a distinct category that shows broader trends in science-industry relations, from a formal point of view they did not constitute a coherent category. The term “institute” was ambiguous and applied to various legal and administrative arrangements. While the French state attempted to unify terminology by introducing “faculty institutes” through the 1920 Decree on the constitution of universities, the measure was not sufficient to englobe all types of institutions. The diversity of organizational realities behind the industrial institutes is, however, useful for analyzing power structures and hierarchies in a given industrial sector. The legal form of an industrial institute was conditioned by the state and the robustness of the industry that funded it. As such, the history of the French industrial institutes may constitute a fertile ground for broader analyses on the impact of power relations on the legal reality behind the initiatives uniting science and industry. 相似文献
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The article presents the results of a study focusing on the family situation, education and interpersonal relations of adults (26–35 years old) who in their adolescence (16–19 years old) displayed exceptional giftedness. One group of those surveyed were national academic award winners (90). The control group consisted of 90 people of no outstanding academic achievement. The research found many differences between these two groups, both in the family situation and in interpersonal relations. High achievers were raised in families of higher social and professional status, and almost 72.2% of them decided to continue their academic career after they had graduated from university. The national academic award winners showed higher scores in shyness and lower scores in sociability in interpersonal relations. 相似文献
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Witas HW Jedrychowska-Dańska K Zawicki P 《Journal of Zhejiang University. Science. B》2007,8(7):512-514
The precise etiology and reasons for the increase in incidence of autoimmune disorders still remain unclear, and although both genetic and environmental factors have been proven to shape individual predisposition, it is not known which of the factors, if not both, is responsible for the boom observed during the last decades. In order to establish whether a higher frequency of autoimmune-predisposing alleles may explain this increase we took advantage of ancient DNA methodology to establish the genetic predisposition, conferred by cytotoxic T lymphocyte associated antigen-4 （CTLA4） ＋49A/G and human leukocyte antigens （HLA） DQBI^57, in population inhabiting Poland in the Middle Ages. After successful typing of 42 individuals from a 12th-14th＇s century archeological burial site, we found that frequencies of the predisposing alleles in the medieval population were higher than they are at present, suggesting thus that the recently observed incidence increase results most probably from factors of other than genetic nature. 相似文献
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Dorota Kostrzewa-Nowak Robert Nowak Zbigniew Jastrz?bski Aleksandra Zar?bska Marta Bichowska Izabela Drobnik-Kozakiewicz ?ukasz Radzimiński Agata Leońska-Duniec Krzysztof Ficek Pawe? Ci?szczyk 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(1):103-113
Background
Numerous data suggest that aerobic-type exercise improves lipoprotein-lipid profiles, cardiorespiratory fitness and body composition in young women. The aim of this study was to evaluate the biological response to high-low impact aerobic fitness among young women.Materials and methods
Thirty-four young women aged 22 (19-24) years were divided into three groups: underweight (N = 10), normal weight (N = 12) and overweight (N = 12). Aerobic capacity, anthropometry and body composition together with complete blood count and lipid profile were determined before and after completion of a 12-week-long training period.Results
The training programme caused a significant decrease in weight (by 4.3 kg, P = 0.003), body mass index (by 1.3 kg/m2, P = 0.003), free fat mass (by 2.1 kg, P = 0.002), total body water (by 0.4 kg, P = 0.036), percentage of fat (by 3 percent points, P = 0.002), all analyzed skinfolds thicknesses, as well as the lipid profile in overweight group, and no changes in normal weight group. Significant changes in weight (by 4.2 kg, P = 0.005), body mass index (by 0.9 kg/m2, P = 0.005), crus skinfold thickness (by 3.3 mm, P = 0.028), and in maximum oxygen uptake (by 2.49 mL/kg/min; P = 0.047) were observed among underweight women. No change in total blood count was observed in all groups.Conclusion
Twelve-week-long fitness training programme of two alternating styles (low and high impact) has a beneficial effect on overweight young women.Key words: body composition, physical fitness, overweight, women 相似文献7.
This article focuses on the problems of adults who in secondary school were high ability learners. The main point of interest of the research presented here is job satisfaction among gifted people and their temperament structure. The authors are interested whether there exist correlations between the investigated variables both in the entire group of gifted individuals as well as in the subgroup of those gifted in the humanities and in the control group. The research results show that between the group of gifted people and the control group there appear significant differences in vigorousness (VG) and activity (AC). The studied groups differ as to the kind and extent of the fulfilment of expectations concerning professional career. Gifted individuals, in comparison to the control group, are more satisfied with their jobs. 相似文献
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Children's Literature in Education - The article is mainly concerned with philosophical interpretations of Astrid Lindgren’s Karlson books. Inspired by Gaare and Sjaastad’s reading... 相似文献
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Teresa Zwierko Wojciech Jedziniak Beata Florkiewicz Miłosz Stępiński Rafał Buryta Dorota Kostrzewa-Nowak 《European Journal of Sport Science》2019,19(5):612-620
The ability to quickly locate objects within the visual field has a significant influence on athletic performance. Saccades are conjugate eye movements responsible for the rapid shift that brings a new part of the visual field into foveal vision. The aim of this study was to investigate the effects of sport expertise and intense physical effort on saccade dynamics during a free-viewing visual search task in skilled soccer players. Two groups of male subjects participated in this study: 18 soccer players and 18 non-athletes as the control group. Two sessions of visual search tasks without a sport-specific design were employed. Eye movements during the visual search tasks were recorded binocularly. Between pre- and post-test sessions, athletes performed a maximal incremental treadmill test. Cardiorespiratory parameters were measured continuously. Capillary lactate samples were collected. Pre-test findings indicated that athletes, in comparison to non-athletes, achieve higher values of the following characteristics of saccades (1) average acceleration, (2) acceleration peak, (3) deceleration peak, and (4) average velocity. An increase in post-test saccade duration and a decrease in post-test saccade velocity was observed in athletes due to the strenuous physical effort in relation to the pre-test state. Athletes may transfer high saccadic function efficiency to non-specific visual stimuli. The findings partially confirm that physical exertion can reduce oculomotor efficiency in athletes. 相似文献