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Jyotsna A. Patil Mandakini S. Kshirsagar Arun J. Patil 《Indian journal of clinical biochemistry : IJCB》2021,36(1):94
Activated carbon fabrics (ACF) mask prevents the absorption of lead and reduce its adverse effects of human health. Aim of this study to know the blood lead level and its effects on heme biosynthesis and hematological parameters after using 2 months activated carbon fabric mask of battery manufacturing workers (BMW). Blood lead level, heme biosynthesis and hematological parameters were measured by using standard method. Blood lead level (P < 0.001, − 13.5%) was significantly decreased, activated δ-aminolevulinic acid dehydratase (P < 0.001, 11.97%) and non-activated δ- aminolevulinic acid dehydratase (P < 0.001, 23.17%) enzyme activity were significantly increased, however, the ratio of activated to Non-activated δ- ALAD (P < 0.001, − 10.13%) was significantly decreased, urinary excretion of δ- aminolevulinic acid (P < 0.001, − 10.49%) and porphobilinogen (P < 0.001, − 7.38%) were significantly decreased after using 2 months ACF mask as compared to before using mask of BMW. Hematological parameters i.e Hb (P < 0.05, 13.42%), PCV (P < 0.05, 7.23%), MCV (P < 0.05, 1.9%) were significantly increased and total WBC count (P < 0.05, − 5.18%) was significantly decreased after using 2 months ACF mask as compared to before using mask of BMW. Two months using ACF mask reduces the blood lead level and improves the δ-ALDH activity and hematological parameters, decreases the urinary excretion of δ-ALA, PBG of battery manufacturing workers. Therefore, the regular using of ACF mask is beneficial to prevent the lead absorption and its adverse effects on human health. 相似文献
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Murali Krishna Madisetty Konda Kumaraswami Shivakrishna Katkam Kankanala Saumya Y. Satyanarayana Raju Naval Chandra Maddury Jyotsna Sujatha Patnaik Vijay Kumar Kutala 《Indian journal of clinical biochemistry : IJCB》2016,31(3):278-285
We aimed to assess whether measuring carotid intima-media thickness (CIMT) and oxidative stress markers such as protein carbonyls, malondialdehyde, nitrate and glutathione in plasma of elderly patients without and with coronary artery disease (CAD) identifies early risk for CAD. A total of 50 cases with cardiovascular risk factors over the age of 60 years without CAD, and 50 patients with angiographically documented CAD over the age of 60 years were included in the study. Control group consists of 200 healthy individuals without the risk factors. Demographic details were obtained from all the subjects and CIMT measured by high frequency ultrasound and oxidative stress markers such protein carbonyls, malondialdehyde and total glutathione were determined in plasma by spectrophotometric methods. The distribution of cardiovascular risk factors in without CAD and CAD cases were smokers (16 vs 56 %), hypertension (26 vs 64 %), diabetes (16 vs 56 %) and dyslipidemia (18 vs 58 %) and positive family history (4 vs 38 %). None of the control group had any cardiovascular risk factors. Among the CAD cases, 16 % had single vessel disease, 44 % had double vessel disease and 40 % had triple vessel disease. The CIMT was significantly increased in CAD cases as compared to cases without CAD and healthy controls. On the other hand, CIMT was significantly increased in cases without CAD as compared to healthy controls. CIMT also increased with the duration of diabetes in patients without CAD and severity of disease in CAD cases. The levels of oxidants like plasma malondialdehyde, protein carbonyls, were significantly elevated and antioxidant glutathione levels and nitrate levels were significantly reduced in cases with and without CAD as compared to healthy controls. Oxidative stress markers and CIMT was found to be significantly increased in patients with cardiovascular risk factors like diabetes, family history of CAD, dyslipidemia, hypertension and smoking when compared to patients without risk factors. In patients with diabetes, CIMT increased as duration of disease increases and also in poorly controlled diabetes. In CAD group, when number of vessel involvement (severity of coronary disease) increases, the CIMT also increases confirming that CIMT is a quantifiable risk factor for CAD. 相似文献
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Few will disagree that teleteaching or teaching using computers and telecommunications technology is becoming increasingly popular among educators. There is much more uncertainty, however, about whether technology is as effective a mode of teaching as its proponents claim. This hesitation in endorsing technology is undoubtedly a result of the inconclusive results of teaching experiments using technology with out an adequate pedagogical base. This paper proposes guidelines for the effective use of technology. These may help the educator to avoid frustrating and stultifying practices that may prejudice the educator and student against using a rich educational resource. While the golden rule urges a two-way constructivist approach to teaching, the ten commandments draw the educator's attention to issues of access, hardware and software selection, learner and teacher preparedness for technology, and human factors in the use of technology 相似文献
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Manorama Swain Preetam Nath Prasant Kumar Parida Jimmy Narayan Pradeep Kumar Padhi Girish Kumar Pati Ayaskanta Singh Bijay Misra Debasis Misra Sanjib Kumar Kar Manas Kumar Panigrahi Chudamani Meher Omprakash Agrawal Niranjan Rout Kaumudee Pattnaik Pallavi Bhuyan Pramila Kumari Mishra Shivaram Prasad Singh 《Indian journal of clinical biochemistry : IJCB》2017,32(3):306-314
Aminotransferase assay is often used as a screening test as well as an endpoint for resolution of disease in nonalcoholic fatty liver disease (NAFLD). Aim of the study was to evaluate the relationship of transaminase level with metabolic variables and histology in NAFLD. Single center observational study was conducted in a gastroenterology clinic at Cuttack in coastal Odisha. Subjects were consecutive patients presenting with functional bowel disease and undergoing abdominal sonography. All participants were evaluated for the presence of metabolic syndrome (MS), insulin resistance, liver function test and lipid profile. Various parameters were compared between NAFLD subjects and controls. 53.5 % of NAFLD had normal serum transaminases, whereas 20.8 % of healthy controls had transaminitis. NAFLD patients had significantly higher BMI, fasting plasma glucose, serum transaminases, serum triglycerides, serum insulin and homeostatic model assessment (HOMA) IR than controls. NAFLD patients who had transaminitis had significantly higher incidence of MS and higher mean HOMA IR than those without. There was no significant difference in histopathological features between NAFLD with and without transaminitis. To conclude, over half of NAFLD subjects do not have transaminitis while transaminitis is present in a fifth of healthy people without fatty liver. Hence serum transaminase should not be used as screening test for NAFLD. NAFLD patients with transaminitis had a higher incidence of MS and insulin resistance than those without. However, there was no significant difference in histopathological features between these two groups. 相似文献
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Mary Renck Jalongo Beatrice S. Fennimore Jyotsna Pattnaik DeAnna M. Laverick Jeffrey Brewster Moses Mutuku 《Early Childhood Education Journal》2004,32(3):143-155
What are the attributes of a high-quality early childhood education program worldwide? An group of experienced early childhood educators that represent diverse international backgrounds attempts to respond to this question by examining six dimensions of quality set forth by the Association for Childhood Education International: (1) philosophies and goals, (2) high-quality physical environments, (3) developmentally appropriate and effective pedagogy and curriculum, (4) attention to basic and special needs, (5) respect for families and communities, (6) professionally prepared teachers and staff, and (7) rigorous program evaluation. The article concludes with an annotated list of references, both in professional publications and online, that examine early childhood education from an international perspective. 相似文献
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Jyotsna Pattnaik 《Early Childhood Education Journal》1996,24(1):11-16
The changes in the social and economic structure of India have intensified the need for universal early childhood education.
The formidable challenges before the Indian Government are: to provide high quality early childhood education programs; to
preserve indigenous practices such as multilinguality, family/community involvement, participation of older children as caretakers
of their younger siblings; and to provide early childhood education to all children despite serious financial constraints.
This article presents a brief overview of the traditional childrearing practices in India, chronicles government initiatives
in early childhood education, describes the range of programs available in India, and identifies goals that will shape the
future of early childhood programs in India.
Portions of this article will appear in Isenberg, J.P., & Jalongo, M.R. (Eds.). (1997, in press).Trends and issues in early childhood: Challenges, controversies, and insights. New York: Teachers College Press. 相似文献
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Early Childhood Education Journal - 相似文献
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Teachers' questions in the inquiry classroom not only explore and make student thinking explicit in the class but also serve to guide and scaffold it. Several studies analysing teachers' questions and their categories have been reported; however the need for a fine-grained analysis has been felt, especially in the inquiry setting. This study attempts a fine-grained analysis of the rich variety of teachers' questions and their roles in an inquiry science classroom, which are illustrated with vignettes from our classes. We present a sequential typology of teachers' questions that emerged from this empirical study, one that brings out their progression in an inquiry class. We juxtapose them with the ones asked during traditional teaching. We also examine, through teachers' self-reports, their motivations for questioning. This work leads towards a characterisation of the complex process of teaching science as an inquiry that teachers interested in moving towards more constructivist teaching practices in their classrooms may find helpful. 相似文献