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1.
Roland Izuagbe Nurudeen Ademola Ibrahim Lilofa Osamienfa Ogiamien Olajumoke Rebecca Olawoyin Nwanne Mary Nwokeoma Promise Ifeoma Ilo Odaro Osayande 《Library & information science research》2019,41(3):100969
Despite the widespread application of technology in the 21st century, making informed decisions regarding its acceptance in organisations is a function of several factors, particularly in developing countries, due to factors such as rising cost of the information technology infrastructure and low technological exposure. A model that incorporated perceived ease of use (PEOU) and e-Skills to examine librarians' intention for actual library technology acceptance was tested. The correlational research design, along with a multistage sampling procedure, was applied to select samples to reduce the sample to a manageable proportion. Professional librarians and library officers in four university libraries provided the data for the study. Results showed that e-Skill is the model's strongest determinant of technology acceptance intention among librarians. Also, PEOU will significantly moderate librarians' intention towards library technology acceptance when e-Skills are insufficient. From these outcomes, the understanding of the determinants of behavioural intention captured in the Technology Acceptance Model (TAM) and the Unified Theory of Acceptance and Use of Technology (UTAT) is extended and refined. 相似文献
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Paul Berry Peter Mathams Beulah Middleton 《International Journal of Disability, Development & Education》1977,24(3):156-164
The study reports the analysis of a mother/child interaction sequence. Its focus is on the mother's teaching strategies. The child was presented with two tasks. The first task was new and not previously experienced by the child; the second task was one that had been experienced. The mother's teaching of the tasks was videotaped and analysed. The material was analysed according to ‘on task’ behaviours. The results indicated that:
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(a) both the mother and child were able to maintain a continuous communication sequence;
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(b) the mother structured both tasks, but structured the new task more, and allowed some flexibility in the old task;
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(c) the language used by the mother was ‘restricted';
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(d) in responding to her child's behaviour, the mother made more use of verbal cues and used fewer non‐verbal cues
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A section of the secondary chemistry curriculum was analyzed to determine the level of cognitive demand of the various aspects of the selected topic. Piagetian levels of thinking of 71 pupils were initially assessed by two group tests, a unit on the mole was taught, and guidelines were used to estimate the level of cognitive operations required by each concept and problem type in the unit. Results of a 23-item test were used to compare the estimated level of cognitive demand of each test item with the Piagetian cognitive level of pupils who were able to answer the item correctly. It was found that pupil cognitive level was positively associated with overall unit test score and with percent success on all test items. Predicted levels of cognitive demand were confirmed for eight items and were within one level for nine additional items. 相似文献
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Beulah F Rohrlich 《Int J Intercult Relat》1979,3(4):487-496
The article presents an overview of the status of women in Western and Eastern Europe during the last decade. Relevant research in English is reviewed. Four indicators of women's status are treated: (1) equality before the law, (2) educational opportunities for women, (3) position in the labor force, and (4) level of leadership in social institutions. Successes and shortcomings in each division are cited; problem areas with presently incomplete information are indicated. The paper makes several recommendations for further research and better dissemination of information. 相似文献
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Kabiru Dauda Zulaikha Busari Olajumoke Morenikeji Funmilayo Afolayan Oyetunde Oyeyemi Jairam Meena Debasis Sahu Amulya Panda 《Journal of Zhejiang University. Science. B》2017,18(11):977-985
Objective
The aim of this study was to formulate polymer-based artesunate nanoparticles for malaria treatment.Methods
Artesunate was loaded with poly(D,L-lactic-co-glycolic acid) (PLGA) by solvent evaporation from an oil-in-water single emulsion. Nanoparticles were characterized by X-ray diffraction and differential scanning calorimetry analyses. In vivo antimalarial studies at 4 mg/kg were performed on Swiss male albino mice infected with Plasmodium berghei. Hematological and hepatic toxicity assays were performed. In vitro cytotoxicity of free and encapsulated artesunate (Art-PLGA) to cell line RAW 264.7 was determined at concentrations of 7.8–1000 μg/ml.Results
The particle size of the formulated drug was (329.3±21.7) nm and the entrapment efficiency was (38.4±10.1)%. Art-PLGA nanoparticles showed higher parasite suppression (62.6%) compared to free artesunate (58.2%, P<0.05). Platelet counts were significantly higher in controls (305 000.00±148 492.40) than in mice treated with free artesunate (139 500.00±20 506.10) or Art-PLGA (163 500.00±3535.53) (P<0.05). There was no sign of hepatic toxicity following use of the tested drugs. The half maximal inhibitory concentration (IC50) of Art-PLGA (468.0 μg/ml) was significantly higher (P<0.05) than that of free artesunate (7.3 μg/ml) in the in vitro cytotoxicity assay.Conclusions
A simple treatment of PLGA-entrapped artesunate nanoparticles with dual advantages of low toxicity and better antiplasmodial efficacy has been developed.7.
AbstractWe present adaptable activities for models of drug movement in the human body – pharmacokinetics – that motivate the learning of ordinary differential equations with an interdisciplinary topic. Specifically, we model aspirin, caffeine, and digoxin. We discuss the pedagogy of guiding students to understand, develop, and analyze models, progressing in complexity to a system of differential equations. We investigate the effects of parameter values that distinguish various health levels, and dosing that may have toxic effects. Our assignments include modeling in a student-centered, active, and increasingly inquiry-oriented setting through which the mathematics and biology inform and reinforce each other. We include supplemental information regarding inquiry methods, student learning outcomes, a student’s commentary about our activities, and support through mathematical communities such as POGIL and SIMIODE. 相似文献
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The article presents an overview of the status of women in Western and Eastern Europe during the last decade. Relevant research in English is reviewed. Four indicators of women's status are treated: (1) equality before the law, (2) educational opportunities for women, (3) position in the labor force, and (4) level of leadership in social institutions. Successes and shortcomings in each division are cited; problem areas with presently incomplete information are indicated. The paper makes several recommendations for further research and better dissemination of information. 相似文献
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A teaching strategy based on the use of manipulative materials as models and analogs of chemical entities, combined with structured peer interaction, was found to enhance learning of two chemistry concepts for both formal and nonformal operational students. Instruction in the control class was based on lectures, CHEM Study laboratories, and individual work. Both cognitive and affective outcomes were more positive in the experimental class. 相似文献
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