Science education for empowerment and social change: A case study of a teacher educator in urban Pakistan     

Rubina Zahur  Angela Calabrese Barton  Bhaskar Raj Upadhyay 《International Journal of Science Education》2013,35(9):899-917

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Electrolyte excretion on prolonged fasting     

Raj Kiran  P. P. Singh 《Indian journal of clinical biochemistry : IJCB》1993,8(1):76-77

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Lipid peroxide levels and antioxidant status in alcoholic liver disease     

Seema Gupta  Rajesh Pandey  Ranjan Katyal  H. K. Aggarwal  R. P. Aggarwal  S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71

The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20 male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT), glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased oxidative stress and compromised antioxidant defense system in patients with ALD.  相似文献   

Effect of low-dose omega-3 fatty acids substitution on blood pressure, hyperinsulinemia and dyslipidemia in Indians with essential hypertension: A pilot study     

A. Bhise  P. V. Krishnan  R. Aggarwal  M. Gaiha  J. Bhattacharjee 《Indian journal of clinical biochemistry : IJCB》2005,20(2):4-9

The present study comprised 100 patients of essential hypertension who were screened for fasting hyperinsulinemia, which was detected in 77% cases. Twenty such hyperinsulinemic cases were subjected to 4 weeks of dietary control phase followed by 6 weeks of omega-3 fatty acids substitution [either 0.6 g/d (group 1) or 1.2 g/d (group 2)]. The mean basal fasting plasma insulin levels were significantly higher (p<0.001) in patients of hypertension when compared to normal controls (126.51±80.36 and 19.35±12.61 μU/ml respectively). At the end of 4 weeks of diet control only, no significant change was observed in any parameter. After substitution of omega-3 fatty acid, a significant reduction of fasting plasma insulin levels in both group 1 (29%) and group 2 (22.8%) was observed (p<0.001). Significant reduction of systolic and diastolic blood pressure (16.4% and 25% respectively), serum cholesterol, triglycerides and low density lipoprotein was also noted in both groups (p<0.001), while high density lipoprotein increased by ∼8 mg% in both groups. Thus omega-3 fatty acid substituion in low dose along-with curtailment of dietary omega-6 fatty acid may be used as an adjunctive measure in the management of essential hypertension.  相似文献   

An institutional theory investigation of U.S. technology development trends since the mid-19th century     

Jason M. Pattit  S.P. Raj  David Wilemon 《Research Policy》2012,41(2):306-318

Drawing on institutional theory, we examine how institutions have influenced technology development trends in the U.S. since the mid-19th century. Based on an inductive analysis of the history of technology development and corporate R&D, we show that both formal and informal institutional rules and constraints played a role in the initial rise of markets for technology, their decline during the early-20th century, and their eventual return at the end of the 20th century. We also find that formal and informal institutions influenced the widespread adoption of in-house R&D labs during the mid-20th century. Our study integrates insights from both the economics and sociology branches of institutional theory. This perspective is particularly useful to analyze historical phenomenon and shifts in trends across long time periods.  相似文献   

Virtual Dissection: An Interactive Anatomy Learning Tool     

Bruce Wainman  Akanksha Aggarwal  Sapriya K. Birk  Jaskaran S. Gill  Katrina S. Hass  Barbara Fenesi 《Anatomical sciences education》2021,14(6):788-798

The novelty of three-dimensional visualization technology (3DVT), such as virtual reality (VR), has captured the interest of many educational institutions. This study’s objectives were to (1) assess how VR and physical models impact anatomy learning, (2) determine the effect of visuospatial ability on anatomy learning from VR and physical models, and (3) evaluate the impact of a VR familiarization phase on learning. This within-subjects, crossover study recruited 78 undergraduate students who studied anatomical structures at both physical and VR models and were tested on their knowledge immediately and 48 hours after learning. There were no significant differences in test scores between the two modalities on both testing days. After grouping participants on visuospatial ability, low visuospatial ability learners performed significantly worse on anatomy knowledge tests compared to their high visuospatial ability counterparts when learning from VR immediately (P = 0.001, d = 1.515) and over the long-term (P = 0.003, d = 1.279). In contrast, both low and high visuospatial ability groups performed similarly well when learning from the physical model and tested immediately after learning (P = 0.067) and over the long-term (P = 0.107). These results differ from current literature which indicates that learners with low visuospatial ability are aided by 3DVT. Familiarizing participants with VR before the learning phase had no impact on learning (P = 0.967). This study demonstrated that VR may be detrimental to low visuospatial ability students, whereas physical models may allow all students, regardless of their visuospatial abilities, to learn similarly well.  相似文献   

Antioxidant and lipid lowering activities of Indian black tea     

Ramesh Chander  A. K. Khanna  Kanwal Raj  A. K. Rastogi 《Indian journal of clinical biochemistry : IJCB》2005,20(1):153-159

Indian black tea; CTC leaf and dust, produced by Tata Tea Limited, Kolkata, (India) was studiedin vitro as potential scavenger of oxygen free radicals. Super oxide anions were generated in a system containing xanthine—xanthine oxidase (enzymic system) and by NADH- phenozine methosulphate (non enzymic system). Anions were assayed in terms of uric acid formation and reduction of nitroblue tetrazolium salt, which were shown to be suppressed by tea extracts. Extracts from both leaf and dust also inhibted the formation of hydroxyl radicalsin vitro in the enzymic system comprising hypoxanthine—Cu⁺²—sodium ascorbate and xanthine oxidase and in non enzymic system of deoxyribose—Cu⁺²—sodium ascorbate and H₂O₂ as well as the Cu⁺² induced lipid peroxidation in human low density lipoprotein. Feeding with black tea in normal rats for sixty days increased their antioxidant activity and their liver microsomes were shown to be protected against peroxidation of lipids as stimulated by metal ions with enzymic or non enzymic reactants. Furthermore feeding with tea extracts in normal as well as triton WR—1339 induced hyperlipidemic rats caused decrease in their plasma levels of total cholesterol, phospholipids and triglycerides. The antioxidant and lipid lowering activities of both extracts from CTC leaf and dust tea was comparable and may be due to the presence of natural products like catechin and others.  相似文献   

Polymorphonuclear leukocytic sialic acid and sialidase activity in obesity     

Raj K. Das  M. G. Muddeshwar 《Indian journal of clinical biochemistry : IJCB》1997,12(2):114-118

The level of sialic acid in the obese polymorphonuclear leukocytes (PMNL) was found to be significantly reduced as compared to normal. Activity of sialic acid degrading enzyme, sialidase, was found to be increased in the obese state. Restoration in both sialic acid content and sialidase activity was also evidenced in the PMNL of treated obese patients.  相似文献   

School Management Teams’ Instructional Leadership Role in Closing the Achievement Gap in Impoverished Schools     

Raj Mestry 《Africa Education Review》2019,16(6):94-110

Abstract

Although the South African government has made numerous strides in addressing equity and social justice in education, significant inequalities still exist in learner performance, especially in many impoverished schools. One of the reasons cited for poor learner achievement is the ineffective leadership role of school management teams (SMTs). This article reports on a study that explored the instructional leadership role of SMTs of public schools with the view to closing the achievement gap in poor performing schools. To gain better insights into the SMTs’ realities and experiences of their work as curriculum leaders, qualitative research located within the interpretivist paradigm was undertaken. The findings revealed that SMTs of impoverished schools exhibit consistently low to moderate instructional leadership competencies which ultimately affect student learning. In order to close the achievement gap in poor performing schools, SMTs should play a more pronounced instructional leadership role by leading and managing core curriculum matters and educational resources effectively and efficiently.  相似文献   

Systematic strategic planning at a State University: A case study of adapting corporate planning techniques     

Raj Aggarwal 《Innovative Higher Education》1987,11(2):123-135

This paper is a study of the adaption of a typical corporate strategic planning process to a university setting. This midwestern state university with over 22,000 students and a number of doctoral, masters, and baccalaureate programs, found that an ongoing planning process with a yearly cycle offers it a number of advantages not avail-able with its prior approaches. It also found that strategic planning is a culture that takes time before it becomes pervasive in any organization.The views expressed in this paper are solely those of the author and do not necessarily represent the viewpoints of any organization.  相似文献