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Mohammad Taha Jalali Abdolhosain Mosavi Honomaror Abdolkarim Rekabi Mahmod Latifi 《Indian journal of clinical biochemistry : IJCB》2013,28(3):277-282
Cardiovascular diseases (CVD) are recognized as major mortality causes and imposes tremendously heavy socio-economic burden worldwide. A vast variety of risk factors have been introduced in the literature known to enhance the incidence of CVD, such as hyperlipidemia. Therefore in order to make an accurate clinical decision it is essential to have appropriate reference ranges for lipids and lipoprotein particles in a particular population. Healthy female (n = 601) and male (n = 617) cases were randomly selected according to certain exclusion criteria from individuals visiting the major University hospital clinics situated in different part of Ahvaz city, Iran, from June 2010 to December 2010. Fasting blood samples (10 ml) were collected and analyzed for total cholesterol, total triglyceride and HDL-C employing enzymatic assays of CHOD-PAP, GPO-PAP and homogenous methods respectively. The samples were obtained such to include the ethnic populations of Persian, Arab. Lore leaving in this city. The data were analyzed statistically by SPSS-18 software. The obtained results were analyzed then age ethnic-wise and reference ranges (mean ± 1SD) were calculated. Remarkable differences between the obtained results for our population with other nations were seen. Also ethnic difference for HDL-C among our cases was noted. The observed significant differences among different nations and ethnicities emphasizes the need for nation-specific, local reference ranges for lipids and lipoproteins particles, to be established. 相似文献
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Maryam J. Jalali Madhavi S. Phadke 《Indian journal of clinical biochemistry : IJCB》2011,26(4):407-412
Conditions like hypertension, atherosclerosis and diabetes are known to be the result of endothelial dysfunction which could
begin early in the life of an individual. The markers of endothelial dysfunction studied in the present work are plasma hemoglobin,
serum high sensitivity C-reactive protein (hsCRP) and plasma nitrite and nitrate. We studied the onset of endothelial dysfunction
with increase in age as well as in disease condition like newly detected hypertensives and of hypertensive diabetic patients.
The mean plasma hemoglobin and hsCRP values were found to increase with age. hsCRP and plasma hemoglobin levels were significantly
higher in patient groups as compared to aged-matched controls. On the other hand nitrate and nitrite was significantly higher
in patients who suffered from both diabetes and hypertension together and nitrate values were significantly lower in patients
who suffered from hypertensive alone. Plasma hemoglobin and hsCRP are associated with endothelial dysfunction and increases
both with age as well as in disease condition. 相似文献
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Concerns have been expressed about the long term inclusion of students with social, emotional and mental health difficulties in mainstream education. Often, this results in continuous referrals with alternative provision. Whilst student views have been explored, there has been a lack of research focusing on perspectives within Primary education. The study aimed to examine whether student views change across Primary and Secondary education. A qualitative design and phenomenological investigation were followed. Through purposive sampling, a total of 13 semi-structured interviews were conducted with students aged 7–16 years from 3 Pupil Referral Units. Using phenomenological data analysis, findings reflect stability in external attributions and supportive factors. However, views about reintegration contrasted with Secondary students expressing low self-worth. Findings highlight mutual perspectives, with conclusions indicating that alternative provision may exacerbate mental health difficulties. Implications include the use of cognitive behavioural frameworks as well as improving shared responsibility between education providers. 相似文献
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