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1.
In this study, freeze-dried water extract from the leaves of Myristica fragrans (Houtt.) was tested for mutagenic and antimutagenic potentials using the Allium cepa assay. Freeze-dried water extract alone and its combination with cyclophosphamide (CP) (50 mg/kg) were separately dissolved in tap water at 500, 1000, 2000, and 4000 mg/kg. Onions (A. cepa) were suspended in the solutions and controls for 48 h in the dark. Root tips were prepared for microscopic evaluation. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radicals’ scavenging power of the extract was tested using butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) as standards. Water extract of Myristica fragrans scavenged free radicals better than BHA, but worse than BHT. The extract alone, as well as in combination with CP suppressed cell division, and induced chromosomal aberrations that were insignificantly different from the negative control (P≤0.05). However, cytotoxic and mutagenic actions of CP were considerably suppressed. The observed effects on cell division and chromosomes of A. cepa may be principally connected to the antioxidant properties of the extract. The obtained results suggest mitodepressive and antimutagenic potentials of water extract of the leaves of M. fragrans as desirable properties of a promising anticancer agent.  相似文献   
2.
Transition services are required by law for students with disabilities in many developed countries. In Malaysia, however, there is still no specific legislation mandating that school‐to‐work transition planning and services be provided to students with disabilities. This study investigated the state of the transition services provided by educational organisations to students with disabilities in Malaysia. A mixed method research design, which utilises both quantitative and qualitative research techniques, was employed to obtain information from 23 government organisations and NGOs involved in the education and training of students with disabilities. This study found that the organisations surveyed were aware of the lack of transition support and call attention to the importance of instituting a national policy on school‐to‐work transition services and supported employment systems for students with disabilities. The legislative and educational implications for Malaysia are discussed.  相似文献   
3.
Litsea elliptica Blume leaves have been traditionally used as medicinal herbs because of its antimutagenicity, che-mopreventative and insecticidal properties. In this study, the toxic effects of L. elliptica essential oil against Sprague-Dawley rat's red blood cells (RBCs) were evaluated. L. elliptica essential oil was given by oral gavage 5 times per week for 3 treated groups in the doses of 125, 250, and 500 mg/(kg body weight), respectively, and the control group received distilled water. Full blood count, RBC osmotic fragility, RBC morphological changes, and RBC membrane lipid were analyzed 28 d after the treatment. Although L. elliptica essential oil administration had significantly different effects on hemoglobin (Hb), mean cell hemoglobin concentration (MCHC), mean cell volume (MCV), and mean cell hemoglobin (MCH) in the experimental groups as compared to the control group (P<0.05), the values were still within the normal range. L. elliptica induced morphological changes of RBC into the form of echinoeyte. The percentage of echinocyte increased significantly among the treated groups in a dose-response manner (P<0.001). The concentrations of RBC membrane phospholipids and cholesterol of all treated groups were significantly lower than those of control group (P<0.001). However, the RBC membrane osmotic fragility and total proteins of RBC membrane findings did not differ significantly between control and treated groups (P>0.05). It is concluded that structural changes in the RBC membrane due to L. elliptica essential oil administration did not cause severe membrane damage.  相似文献   
4.
With numerous benefits of utilising mobile social network sites (SNSs) for learning purposes, limited studies have been conducted to determine the factors that influence the adoption of mobile SNSs in facilitating learning. Accordingly, the main purpose of this study is to explore the determinants of students’ behavioural intention to use mobile SNSs for their pedagogical purposes by utilising an extended version of Technology Acceptance Model. Furthermore, the moderating effect of users’ experience on their behavioural intention was investigated. Using a structured questionnaire, data were collected from 600 students from top-five public universities of Malaysia. The results revealed perceived task-technology fit as the great predictor of users’ intention and perceived usefulness. Although the moderating impact of students’ experience on the model found to be positive, it was not supported in this study. The contributions of this study both to the literature and practice are discussed.  相似文献   
5.
The book describes a five‐year teacher education programme at US's University of New Hampshire (unh ). It includes several research articles about what supports the programme, especially the internship (teaching practice) component, which is a full year long. The book is useful for educators especially those involved in teacher training and preparation. If the content of this book is likely to be relevant to you, I recommend that you arrange to borrow a copy for a while. Othman N Alsawaie  相似文献   
6.
本建立了一维数值模型来模拟顺直冲积渠道的冲刷过程.模型考虑了床沙的非均匀性、床面形态变化,应用该模型预测计算了冲刷过程中的床沙级配变化.模型计算结果表明床沙粗化过程不仅与水流的水力特性有关,还与床沙的颗粒大小及分布有关.模型计算结果与2组非均匀床沙水槽试验结果进行了比较,结果表明模型计算结果与试验结果符合得较好.  相似文献   
7.
In this paper the results of a study conducted to determine the perception of counselling needs by primary school teachers in Malaysia and Lesotho are reported. To this end, teachers were asked about the special needs of students they teach, how they cope with these students, what assistance they would like to have in teaching, and the best approach for dealing with student concerns. Teachers in Lesotho are dealing with larger numbers of special needs students and thus are having more difficulties than Malaysian teachers. Malaysian teachers appeared to be more interested in improving their teaching effectiveness. There was some variation in the perceptions of how to best deal with student concerns.  相似文献   
8.
The book describes a five‐year teacher education programme at the University of New Hampshire. It includes several research articles about what supports the programme, especially the internship (teaching practice) component, which is a full year long. The book is useful for educators, especially those involved in teacher training and preparation. If its content is likely to be relevant to you, I recommend you borrow a copy for a while. Othman N Alsawaie  相似文献   
9.
A thorough understanding of chemical bonding requires familiarity with the particulate nature of matter. In this study, a two‐tier multiple‐choice diagnostic instrument consisting of ten items (five items involving each of the two concepts) was developed to assess students’ understanding of the particulate nature of matter and chemical bonding so as to identify possible associations between students’ understandings of the two concepts. The instrument was administered to 260 Grades 9 and 10 students (15–16 years old) from a secondary school in Singapore. Analysis of students’ responses revealed several alternative conceptions about the two concepts. In addition, analysis of six pairs of items suggested that students’ limited understanding of the particulate nature of matter influenced their understanding of chemical bonding. The findings provide useful information for challenging students’ alternative conceptions about the particulate nature of matter during classroom instruction in order to enable them to achieve better understanding of chemical bonding.  相似文献   
10.
This is an intervention study that explored the effect of using video lesson analysis methodology (VLAM) on the ability of prospective middle/high school mathematics teachers to analyze mathematics teaching. The sample of the study consisted of 26 female prospective mathematics teachers enrolled in a methods course at the United Arab Emirates University. The participants were divided equally into two groups, experimental and control. The experimental group was involved in video lesson analysis where they analyzed ten video lessons throughout the semester. The group members interacted via discussion forums through Blackboard technology. Both groups wrote analyses of two video lessons, one before the intervention program and another at the end of it. It was found that the intervention remarkably improved the ability to analyze mathematics teaching of the experimental group while little improvement occurred to the control group. Implications for teacher education programs are discussed.  相似文献   
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