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Patricija Bankovic Radovanovic Marija Kocijancic 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(2):230-236
Introduction
Preanalytical errors still constitute the largest source of errors in laboratory work. Proper patient preparation and patient’s knowledge about a particular procedure affects its accuracy and reliability. We hypothesized that most of pregnant women are not well enough informed about the proper procedure for the OGTT. The aims of this study were to investigate: (i) how well pregnant women are informed about the OGTT; (ii) the most common way to inform pregnant women about OGTT and (iii) whether pregnant women’s level of knowledge about the OGTT differ regarding source of information.Materials and methods
The anonymous questionnaire was conducted across the country in 23 Croatian primary and secondary healthcare centres. The questionnaire contained 9 questions on certain demographic data and familiarity with OGTT procedure. All 343 participants filled the questionnaire before the first blood draw.Results
42% of the participants demonstrated high and 38% adequate level of knowledge about the OGTT procedure. Majority of participants were informed about the procedure by gynaecologist (56%). The level of knowledge differed among participants with different sources of information (P = 0.030). Further analysis showed that the level of knowledge was lower in pregnant women having received information from their gynaecologist compared to pregnant women who received information from the laboratory staff.Conclusions
In general, pregnant women are familiar with OGTT procedure, main source of information about the OGTT procedure is their gynaecologist, but the level of knowledge was higher in women who received information about the OGTT procedure from the laboratory staff.Key words: preanalytical phase, oral glucose tolerance test, survey, patient education, gestational diabetes 相似文献2.
Kasum M Oreskovic S Zec I Jezek D Tomic V Gall V Adzic G 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(2):171-179
Hypersecretion of prolactin by lactotroph cells of the anterior pituitary may lead to hyperprolactinemia in physiological, pathological and idiopathic conditions. Most patients with idiopathic hyperprolactinemia may have radiologically undetected microprolactinomas, but some may present other causes of hyperprolactinemia described as macroprolactinemia. This condition corresponds to the predominance of higher molecular mass prolactin forms (big-big prolactin, MW > 150 kDa), that have been postulated to represent prolactin monomer complexed with anti-prolactin immunoglobulins or autoantibodies. The prevalence of macroprolactinemia in hyperprolactinemic populations between 15-46% has been reported. In the pathophysiology of macroprolactinemia it seems that pituitary prolactin has antigenicity, leading to the production of anti-prolactin autoantibodies, and these antibodies reduce prolactin bioactivity and delay prolactin clearance. Antibody-bound prolactin is big enough to be confined to vascular spaces, and therefore macroprolactinemia develops due to the delayed clearance of prolactin rather than increased production. Although the clinical symptoms are less frequent in macroprolactinemic patients, they could not be differentiated from true hyperprolactinemic patients, on the basis of clinical features alone. Although gel filtration chromatography (GFC) is known to be the gold standard for detecting macroprolactin, the polyethylene glycol precipitation (PEG) method has offered a simple, cheap, and highly suitable alternative. In conclusion, macroprolactinemia can be considered a benign condition with low incidence of clinical symptoms and therefore hormonal and imaging investigations as well as medical or surgical treatment and prolonged follow-up are not necessary. 相似文献
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Slavko Cvetek 《欧洲师范教育杂志》2008,31(3):247-256
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Gregor Cerinsek Tina Hribar Natasa Glodez Slavko Dolinsek 《International Journal of Science Education》2013,35(17):2999-3025
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Marija Kocijancic Jelena Cargonja Alma Delic-Knezevic 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(3):368-375
Introduction:
Preanalytical variables account for most of laboratory errors. There is a wide range of factors that affect the reliability of laboratory report. Most convenient sample type for routine laboratory analysis is serum. BD Vacutainer® Rapid Serum Tube (RST) (Becton, Dickinson and Company, Franklin Lakes, NJ, USA) blood collection tube provides rapid clotting time allowing fast serum separation. Our aim was to evaluate the comparability of routine chemistry parameters in BD Vacutainer® RST blood collection tube in reference with the BD Vacutainer® Serum Separating Tubes II Advance Tube (SST) (Becton, Dickinson and Company, Franklin Lakes, NJ, USA).Materials and methods:
Blood specimens were collected from 90 participants for evaluation on its results, clotting time and stability study of six routine biochemistry parameters: glucose (Glu), aspartate aminotransferase (AST), alanine aminotransferase (ALT), calcium (Ca), lactate dehidrogenase (LD) and potassium (K) measured with Olympus AU2700 analyzer (Beckman Coulter, Tokyo, Japan). The significance of the differences between samples was assessed by paired t-test or Wilcoxon Matched-Pairs Rank test after checking for normality.Results:
Clotting process was significantly shorter in the RSTs compared to SSTs (2.49 min vs. 19.47 min, respectively; P < 0.001). There was a statistically significant difference between the RST and SST II tubes for glucose, calcium and LD (P < 0.001). Differences for glucose and LD were also clinically significant. Analyte stability studies showed that all analytes were stable for 24 h at 4 °C.Conclusions:
Most results (except LD and glucose) from RST are comparable with those from SST. In addition, RST tube provides shorter clotting time. 相似文献7.
Due to the broad acceptance of the Programme for International Student Assessment (PISA) and other comparative studies as instruments of policymaking, its accuracy is essential. This article attempts to demonstrate omissions in the conceptualisation, and consequently in calculation and interpretation, of one of the central points of PISA 2006 and 2009. The authors point to the danger of such omissions for possible evidence-based education policymaking. With regard to the reproduction of social inequalities through education, we focus on variance in student performance between schools and within schools on the science scale (PISA 2006) and in the mother tongue (PISA 2009). The thesis of the PISA study is that there are countries (Finland, Iceland and Norway) where between only 14 and 29% of the average OECD variance (33%) is attributed to between-school variance – which is good – and there are countries (Germany, Bulgaria, Austria, Hungary, Belgium, Slovenia, the Netherlands, etc.), where the variance between schools is at least ‘one-and-a-half times that of the OECD’ – which is bad. For Slovenia, we demonstrate a significantly different share of variance explained by between-school variance of the same or similar cohort if we move the point of research by only nine months. Our main argument is that such a difference in the share of variance is not the result of a substantial change in the results (grooving difference in the performance) but the result of formal organisational change – the transition of the cohort to upper secondary education. The difference in calculations also radically changes policy implications, which is crucial. While PISA data suggest the necessity of policy measures to reduce between-school variance, our calculations suggest the need for reconsideration of policy measures aimed at the reduction of within-school variance, gender differences, and differences in performance between native and immigrant students. 相似文献
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Slavko Splichal 《传播与批判/文化研究》2013,10(2):95-115
The paper develops the argument of two faces of censorship as a form of symbolic violence over individuals directed either inward or outward. In both instances, the resistance to disclosure and an effort to keep things hidden are normally complemented by strategic control over the process of making things visible. Silence is usually considered a sign of censorship, but in reality it can indicate not only the suppression of, but also a resistance to, communication. Despite the changes leading toward the “structural censorship” in modern complex societies, the essential questions remain: What are the strategies to confront the (hidden) forces of censorship, and how successful can they be? 相似文献
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