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High-resolution magnetic resonance (MR) imaging today allows the in vivo quantification of the surface area of the cortex covering the planum temporale and permits assessment of the direction and degree of individual left-right asymmetry of this structure. This methodologic advance is promoting new studies on the biological mechanisms of anatomic and functional lateralization and on the structural accompaniments of disorders such as developmental dyslexia. It is important to stress that studies must agree on the definition and measurement of planum asymmetry, and we review our definition and its justification in the present article.Data obtained from normal subjects supported the assumption that planum (a)symmetry underlies functional lateralization. Thus, familial sinistrality predicted for symmetry of the planum in all eight left-handers studied. The pattern of planum symmetry in the normals was similar to that found in the post mortem studies of dyslexic individuals. Insofar as hand preference and developmental dyslexia are in part genetically transmitted, we suggest that planum symmetry may represent an inherited condition as well. Further-more, even though planum symmetry is part of the anatomic substrate of developmental dyslexia, it is unlikely that it represents a form of developmental anatomic pathology.  相似文献   
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OBJECTIVE: To determine the prevalence of a history of child sexual abuse (CSA) in a random sample of adult patients presenting for routine health care to family practice clinics in Israel. METHOD: One thousand and five randomly selected patients aged 18 to 55, attending 48 clinics, participated in this questionnaire study. RESULTS: Twenty-five percent indicated that they had been sexually abused as children. More women reported CSA (p < .0001 ) than men, as did women originating from Western countries (p = .02) and those with more than 12 years of education (p = .01). There were no significant associations between CSA and the other socio-demographic variables examined. Fondling was the most common and intercourse the least common activity experienced. Forty-five percent of the perpetrators were previously known. The mean age at which the child sexual abuse began varied between 10 and 14. Only 45% of the subjects had ever told anyone about the experience. CONCLUSIONS: Since no other prevalence study has been reported to date in Israel, these findings suggest that as in other Western countries CSA is a relatively common problem. Family physicians and other health professionals should be aware of this high prevalence and its known potential for initial and long-term deleterious outcomes.  相似文献   
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Delay eye-blink conditioning is an associative learning task that can be utilized to probe the functional integrity of the cerebellum and related neural circuits. Typically, a single interstimulus interval (ISI) is utilized, and the amplitude of the conditioned response (CR) is the primary dependent variable. To study the timing of the CR, an ISI shift can be introduced (e.g., shifting the ISI from 350 to 850 ms). In each phase, a conditioned stimulus (e.g., a 400- or 900-ms tone) coterminates with a 50-ms corneal air puff unconditioned stimulus. The ability of a subject to adjust the CR to the changing ISI constitutes a critical timing shift. The feasibility of this procedure was examined in healthy human participants (N = 58) using a bidirectional ISI shift procedure while cortical event-related brain potentials were measured. CR acquisition was faster and the responses better timed when a short ISI was used. After the ISI shift, additional training was necessary to allow asymptotic responding at the new ISI. Interestingly, auditory event-related potentials to the CR were not associated with conditioning measures at either ISI.  相似文献   
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Classical eyeblink conditioning (EBC) has been widely used to probe cerebellar function in humans and nonhuman mammals. Although the neural pathways governing behavior in this task are well understood and fairly discrete, it remains unclear in the human literature how conditioned stimuli (CSs) of different modalities (e.g., visual and auditory) influence the exhibition of conditioned responses (CRs). In the present study, therefore, CRs to a visual CS and an auditory CS were examined with the single-cue delay EBC procedure. An initial experiment (N=61) was conducted to identify visual and auditory stimuli that had equal perceived intensities. Using these perceptually equivalent stimuli, a second group of 25 subjects completed auditory and visual EBC procedures in two testing sessions 5–8 days apart. Whereas the acquisition of CRs was similar between the CS modality conditions, the timing of the CRs differed such that earlier CR onset and peak latencies were associated with the visual CS. In addition, CR timing improved across testing sessions, as indicated by the later CR peak latencies exhibited during the second testing session, as compared with the first.  相似文献   
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More women are now entering male-dominated fields, yet, science, technology, engineering, and mathematics (STEM) remain dominated by men. We examined the association between boys’ and girls’ STEM choices after secondary education and friends’ gender norms, and whether pressure to conform to traditional gender norms differs depending on the gender composition of the friend group. Drawing on 3 waves of longitudinal data (N?=?744) from the Netherlands, our sample consists of adolescents in STEM trajectories in secondary education. Their retention in STEM after secondary education gives us a better understanding of gender-specific “leakage” from the STEM pipeline. We found that girls’ likelihood of choosing STEM decreased drastically when friends had more traditional gender norms. Friends with traditional gender norms had less effect on boys. Nonetheless, boys with only same-sex friends were more likely to enter STEM. Our findings indicate that an environment with gender-normative ideas pushes girls out of the STEM pipeline.  相似文献   
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Designing collaborative multiplayer serious games   总被引:1,自引:0,他引:1  
The idea of Computer Supported Collaborative Learning (CSCL) is being investigated for more than twenty years. Since a few years, game-based approaches like video games for learning (Serious Games) offer new fields of application. The combination of game-based learning concepts and collaborative learning may enable new, game-based application areas of CSCL, like collaborative multiplayer Serious Games. Designing such games, however, is very challenging as it requires to take into account traditional single player game design concepts, concepts for multiplayer game design, and concepts for Serious Game design simultaneously. Only very few examples of such games exist today. In this paper we describe an approach for the design of game-based collaborative learning scenarios using multiplayer Serious Games. Our approach aims at combining design concepts from the fields of collaborative learning and (multiplayer) game design. Our approach takes into account the requirements of traditional single player games (fun, narration, immersion, graphics, sound), challenges of multiplayer games (concurrent gaming, interaction) and Serious Game design (seamless inclusion of learning content, adaptation and personalization). Furthermore, requirements of collaborative learning are considered, like group goals, positive interdependence, and individual accountability. Our design concept was used to create a collaborative 3D multiplayer game fostering collaborative behavior as a foundation for game-based collaborative learning in small teams. We performed a user study with eight gaming sessions and a total of 23 participants. Results showed that the game enables a collaborative gameplay and fosters collaborative behavior. This may allow us to use a game-based CSCL approach to combine the advantages of game-based learning with those of collaborative learning in future.  相似文献   
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The aim of this study was to compare the somatotype and size of elite female basketball players in terms of playing position and team performance. Anthropometry and somatotype data were collected on 168 players from 14 countries before the Women's World Basketball Championship, Australia, 1994. There were 64 guards (mean?±?s: age 25.4?±?3.3 years, height 1.72?±?0.06?m, mass 66.1?±?6.2?kg, somatotype?=?2.9?–?3.9?–?2.6), 57 forwards (age 25.2?±?3.8 years, height 1.81?±?0.06?m, mass 73.3?±?5.9?kg, somatotype?=?2.8?–?3.5?–?3.2) and 47 centres (age 24.1?±?3.1 years, height 1.90?±?0.06?m, mass 82.6?±?8.2?kg, somatotype?=?3.2?–?3.1?–?3.4). Mean somatotypes by position were significantly different (F?=?7.73, P?<?0.01). Guards had greater mesomorphy than centres and less ectomorphy than forwards and centres. When discriminant function analysis was applied to endomorphy, mesomorphy, ectomorphy, age, height and mass, only height, mass and ectomorphy entered (Wilks' λ?=?0.351, F?=?31.40, P?<?0.000), 70% of the variance was accounted for, and 72% of players were correctly classified. In the four top versus four bottom teams, guards were taller and more ectomorphic, forwards were taller, with lower mesomorphy and higher ectomorphy, and centres did not differ. Thus there are some differences in somatotypes by position and team placing, but the combination of height, mass and ectomorphy provide the best differentiation by position.  相似文献   
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Cart.  AB 《科学中国》1989,(11):1-8
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