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N. Unni C. Sumithra R. Lakshman Lakshmi N. Leela Menon K. N. Subhakumari V. S. Sheejamol 《Indian journal of clinical biochemistry : IJCB》2015,30(2):161-166
PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular disease. Our aim is to evaluate the oxidant status and hsCRP levels in PCOS. The study involved 61 cases and 61 controls in the age group of 18–40 years diagnosed with PCOS. Erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), serum hsCRP, gonadotrophins, thyroid stimulating hormone, prolactin, glycemic status and lipid profile were estimated. Erythrocyte MDA (p < 0.001), SOD (p = 0.007) and serum hsCRP (p < 0.001) were significantly elevated in PCOS patients than controls. Oxidative stress is present in women with PCOS along with elevated hsCRP. 相似文献
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This paper investigates changes in bullying behaviour among pupils in 72 Norwegian compulsory schools two years after the schools completed an anti‐bullying program. A sample of 22 schools received eight lesson plans with material for staff to use to focus on the challenges of anti‐bullying during this period of two years. Another sample of 22 schools received the same lessons, and also received regular phone calls from a researcher between the lessons. A sample of 28 schools received no other attention than the surveys. We assumed that bullying would be lower in the schools which received follow‐up procedures than in the control schools. Results showed no overall change in mean victimisation scores (i.e., being the victim of bullying), although there was a slight but significant overall decrease in bullying scores (i.e., bullying others) (F = 12.58, p < .001). Our predictions of differences between the samples were not supported. One possible conclusion is that the follow‐up procedures offered were not sufficient to decrease bullying any further. Further research is needed to determine whether the lack of effect is due to the type of follow‐up measure or to implementation within schools. 相似文献
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P. Rani K. Meena Unni J. Karthikeyan 《Indian journal of clinical biochemistry : IJCB》2004,19(2):103-110
The present paper focuses on assessing the levels of various enzymatic and non-enzymatic antioxidants in selected berries
of Indian sub-continent viz., gooseberry, grapes, orange and tomato. This study has revealed that orange, tomato and grapes
possess predominant quantities of enzymatic antioxidants namely SOD, catalase and glutathione peroxidase respectively. The
levels of antioxidants analyzed namely reduced glutathione, vitamin C and vitamin A were maximal in grapes, orange and tomato
respectively. All the extracts of berries included in the present study inhibited iron inducedin vitro lipid peroxidation in erythrocytes, the extend of inhibition being highest for gooseberry and orange compared to tomato and
grapes which could be attributed to their in-built antioxidant system. 相似文献
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Product design is the convergence point for engineering and design thinking and practices. Until recently, product design has been taught either as a component of mechanical engineering or as a subject within design schools but increasingly there is global recognition of the need for greater synergies between industrial design and engineering training. Product design engineering (PDE) is a new interdisciplinary programme combining the strengths of the industrial design and engineering. This paper examines the emergence of PDE in an environment of critique of conventional engineering education and exemplifies the current spread of programmes endorsing a hybrid programme of design and engineering skills. The paper exemplifies PDE with the analysis of the programme offered at Swinburne University of Technology (Australia), showing how the teaching of ‘designerly’ thinking to engineers produces a new graduate particularly suited to the current and future environment of produce design practice. The paper concludes with reflections on the significance of this innovative curriculum model for the field of product design and for engineering design in general. 相似文献
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The current popular case against the use of standardised ability tests in bilingual assessment is not as unequivocal as may be commonly assumed. Evidence currently available indicates that such tests generally measure the same constructs, with equal accuracy, regardless of language backgrounds. The purpose of this paper is to contribute to this debate by presenting a detailed comparison of the Illinois Test of Psycholinguistic Ability (ITPA) profiles of monolingual language‐impaired children who have received the diagnosis ‘specifically language‐impaired’ (SLI) (N = 95) and ITPA profiles of bilingual children who are referred for assessment of their language problems (N = 43). It is concluded that most bilingual children suffer from a ‘knowledge‐based’ problem, while most monolingual children suffer from a more fundamental ‘processing‐based’ problem. By presenting this analysis, we hope to contribute to the general debate about whether this commonly used test can be used in the assessment of bilingual children. 相似文献
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Characterization and separation of Cryptosporidium and Giardia cells using on-chip dielectrophoresis
Narayanan Unni H Hartono D Yue Lanry Yung L Mah-Lee Ng M Pueh Lee H Cheong Khoo B Lim KM 《Biomicrofluidics》2012,6(1):12805-1280514
Dielectrophoresis (DEP) has been shown to have significant potential for the characterization of cells and could become an efficient tool for rapid identification and assessment of microorganisms. The present work is focused on the trapping, characterization, and separation of two species of Cryptosporidium (C. parvum and C. muris) and Giardia lambia (G. lambia) using a microfluidic experimental setup. Cryptosporidium oocysts, which are 2-4 μm in size and nearly spherical in shape, are used for the preliminary stage of prototype development and testing. G. lambia cysts are 8–12 μm in size. In order to facilitate effective trapping, simulations were performed to study the effects of buffer conductivity and applied voltage on the flow and cell transport inside the DEP chip. Microscopic experiments were performed using the fabricated device and the real part of Clausius—Mossotti factor of the cells was estimated from critical voltages for particle trapping at the electrodes under steady fluid flow. The dielectric properties of the cell compartments (cytoplasm and membrane) were calculated based on a single shell model of the cells. The separation of C. muris and G. lambia is achieved successfully at a frequency of 10 MHz and a voltage of 3 Vpp (peak to peak voltage). 相似文献
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The focus of this article is to explore the role of the principal in promoting school development activity (SDA) in Norwegian compulsory schools. The sample included 81 schools from 42 randomly selected municipalities. Results suggest that the principal can promote SDA among the teaching staff by playing an active role in creating an innovative culture at school. Moreover, results suggest that the principal may have a more important role in promoting SDA in secondary than in primary schools. Finally, results indicate that support from local authorities was related to SDA involvement among secondary school principals, whereas it was unrelated to such involvement among primary school principals. 相似文献
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In 2002 the Prime Minister of Norway initiated a central Manifesto against bullying and invited all schools to participate
in anti-bullying programs. Two programs were supported by the central authorities. This paper draws on a Norwegian project
where six compulsory schools participated in one of those programs. Our focus was on the implementation process in the schools.
We wanted to see how the schools’ readiness for the program influenced the implementation. Group interviews with the project
groups at the schools and telephone interviews with the headteachers were used to collect data. Results indicate that the
headteacher’s role is important, during both initiation and implementation of the program. The schools that were familiar
with anti-bullying work and had firm leadership seem to have implemented the program most successfully. One lesson from this
study is the need to investigate differentiated implementation support for different schools depending on their readiness. 相似文献
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Jarmund Veland Unni Vere Midthassel Thormod Idsoe 《Scandinavian Journal of Educational Research》2013,57(6):515-531
This paper is based on a study of 7,372 students in grades 5–10 (aged 11–16) in a representative sample of Norwegian compulsory schools. The aim of the study was to examine the relationship between students' reported socio‐economic status (SES) and their perceived social inclusion (SI) in school in the whole sample. We also considered separately a sub‐sample of students with additional social background disadvantages, i.e. children taken into public care and placed in a foster home or children's home, those whose parents have alcohol‐ or drug‐related problems, or students who are refugees and belonging to ethnic minority groups. For the sample as a whole, results showed a weak but significant relationship between SES and SI. In the disadvantaged sample, this relationship is stronger. These results suggest that additional social background disadvantages intensify the effects of SES on perceived social inclusion in school. 相似文献
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