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1.
The objective of this study was to evaluate acrosin activity in spermatozoa of infertile Nigerian men and to compare with those of the fertile men. The acrosin activity was evaluated using the Acroscreen reagent kit. The acrosin activity of the fertile men was 40.7±5.2 mIU/106 sperm (range 30.1–51.3) and those of the infertile men was 22.4±8.33 mIU/106 sperm (range 5.7–39.1). The difference in the mean was statistically significant (P<0.001). There was a subpopulation of the infertile men who had their acrosin activity within normal range of the fertile men, 32.9±1.57 mIU/106 sperm. But the difference in the mean was statistically significant (P<0.001). Acrosin activity decreased with increased morphological changes in the spermatozoa. It is concluded that acrosin activity in the infertile Nigerian men is significantly lower than that in the fertile men. Acrosin activity may also be affected by morphological changes in the spermatozoa.  相似文献   
2.
U.S. federal websites are required to be accessible for people with impairments. However, despite the existing regulations and guidelines, many federal websites continue to be inaccessible, and accessibility policy statements available on federal websites often do not provide any useful information. This paper provides three contributions to the research literature: (1) an accessibility evaluation of 100 federal home pages using both human and automated methods, (2) a content analysis of existing website accessibility policy statements, and (3) a discussion of the relationship between actual Section 508 compliance and the existing accessibility policy statements on a website. The paper concludes with recommendations for improving policy related to Section 508 compliance for websites.  相似文献   
3.
The HIV/AIDS pandemic is recognized globally as the greatest health challenge of the present generation. It is widely acknowledged to be the foremost killer disease in Africa. Since the first Aids case was publicly announced in 1986, the astronomical increase in victims has been a matter of concern. The rates of HIV/AIDS infection indicate that Nigeria currently has the third largest rate of HIV/AIDS patients. The UNAIDS (2008) reported that as at 2007, the population of children and adults with HIV/AIDS in Nigeria was 2.6 million. Due to the fact that there is no cure for the virus, HIV/AIDS, counselling is an important aspect of its management. Counsellors in Nigeria have provided pre- and post-test counselling, preventive education seminars, and referrals to other health professionals. However, counsellors’ efforts have only yielded limited success because of a number of major challenges. This paper examines some of the challenges involved in meeting the HIV/AIDS counselling needs of Nigerians. Specifically, it addresses challenges faced by government, potential clients, and the Counselling Association of Nigeria, as well as challenges associated with existing cultural practices (indigenous counselling practices). It concludes with specific recommendations for various stakeholders.  相似文献   
4.
Proteinuria in subjects with sickle cell anaemia (SCA) is an indication of an ongoing renal insufficiency and it’s prevalence varies between sexes. We evaluated sex differences in the activities of Lecithin: cholesterol acyltransferase (LCAT), Lipoprotein lipase (LPL) and the levels of lipoproteins in SCA patients with proteinuria. Fifty SCA patients (30 males aged: 26.4 ± 7.3 years and 20 females, aged 25.4 ± 2.6 years) and 50 age and sex matched control SCA patients were recruited for the study. Random urine specimens were collected and tested for the presence of albumin by urine dipstick technique. A 24 h urinary protein was quantitated using sulphosalicylic acid technique. Fasting serum total cholesterol, triglyceride, urea and creatinine were determined using enzymes catalyzed colorimetric methods. HDL cholesterol was determined in the supernatant after precipitation with manganese chloride–phosphotungstic acid solution. LCAT was measured using the Anasolv LCAT assay with proteoliposome as substrate. LPL was determined by incubating the serum in glyceryl trioleate substrate, the glycerol liberated was measured in an aliquot of the incubating mixture. In male SCA controls there was 18.2 and 6.9% increase in the activities of LPL and LCAT respectively when compared with females but in SCA patients with proteinuria there was 8.4 and 5.2% decreases in the male SCA patients compared with females. The concentration of 24 h urine protein in the SCA male subjects with proteinuria was significantly higher (0.25 g/day; P < 0.001) compared with the SCA female patients with proteinuria (0.09 g/day). There are sex differences in the activities of LCAT and LPL in SCA patients with proteinuria. Metabolism of these lipolytic enzymes may be modulated differently in SCA patients with proteinuria.  相似文献   
5.
This article examines the practical ways of handling Internet connectivity challenges in a typical university academic library setting in Nigeria, using Kenneth Dike Library (KDL), University of Ibadan, as a case study. Both internal and external factors are responsible for the challenges being experienced in terms of Internet connectivity in KDL. The current state of Internet connectivity within the KDL is presented. Also discussed are an overview of the previous model of Local Area Network (LAN) within the KDL, the challenges associated with the previous model, an overview of the new LAN model and discussion/way forward. Finally, conclusion and recommendations are presented.  相似文献   
6.
Education and Information Technologies - The Almajiri children in Nigeria are deserving of special interventions to reduce the life-long divide in educational achievement, social status, and...  相似文献   
7.
This study was conducted to investigate the diagnostic performance characteristics of prostate specific antigen (PSA) by comparing serum PSA value with histological findings in patients suspevted of having prostate cancer in Aminu Kano Teaching Hospital. Nigeria. Clinical and Laboratory records were examined and collated for serum PSA values, together with histological findings of biopsy specimen, clinical diagnosis, age of patients, and mode of presentation. The serum PSA values were determined by ELECSYS 1010 autoanalysers Roche, Germany based on electrochemiluminescence immunoassay technique. The results show that serum PSA values increase with age in the assymptomatic non-cancer patients who came for medical check up but were within normal limit. In prostatic disease conditions PSA values were raised in benign prostatic hyperplasia 35.957± 4.0315ng/ml, in undifferentiated carcinoma 56.22±4.295ng/ml and adenocarcinoma >100ng/ml as compared to the normal range (0–4ng/ml). These cases were confirmed by histological diagnosis. It is concluded that PSA evaluations is a sensitive marker for prostate cancer but because of various other conditions that affect serum PSA concentration, other methods of investigations such as Digital Rectal examination, Trans Urethral Ultra-Sonography and histological examination should be combined to confirm diagnosis. Prognosis of patients will be better if early diagnosis is made.  相似文献   
8.
Abstract

Retrospective conversion of bibliographic records is not a recent practice among Nigerian academic libraries. However, the end product of this process, which is a functional Online Pubic Access Catalog (OPAC) has been underwhelming. This is due to various challenges that have hindered the libraries from achieving a successful retrospective conversion. Some of these challenges include unreliable software, lack of a union catalog, and sheer absence of exchange of information among the libraries. This study therefore measures the practices and experiences of twenty Nigerian University Libraries in the course of carrying out retrospective conversion of their resources using the KOHA library software. The study adopted a survey method of research with a self-developed questionnaire as the instrument of data collection. Data analysis was with the aid of the SPSS software and the presentation was done using simple frequency and percentage. Findings show that erratic power supply and low Internet bandwidth are the major challenges facing Nigerian libraries in the course of retrospective conversion.  相似文献   
9.
New information communication technologies, such as the Internet and electronic publishing, not only enhance the range of publications that libraries can provide for their users but also increase the speed with which such requests can be met. This article describes the development of electronic document delivery (EDD) at the Kenneth Dike Library at the University of Ibadan, Nigeria. A successful EDD program depends upon good intranet and Internet network systems, document availability, user awareness and training, and ease of use. The major challenge to this service is inconsistent power supply, which the university is addressing with the aid of a grant from the MacArthur Foundation for backup electric generators and a university solar energy project. It is hoped that this will assure better and more reliable power service in support of EDD in future. New information delivery regulations and laws guiding adequate service will also emerge but must be properly applied for effective and positive results.  相似文献   
10.
This article reports on a survey study on the adoption and implementation of automation projects in federal university libraries in the south-west of Nigeria (SWN). The objectives are to ascertain the implementation status of automation projects, discuss the accruable benefits, investigate the library management system software being used, determine the modules already activated and fully implemented and their web presence, highlight the challenges encountered, draw conclusions and recommendations on enhancing successful implementation of library automation projects in Nigeria. The method used for gathering data for the study is questionnaire-based survey, using google form template. The findings of the study are that all the six federal university libraries in the SWN have adopted and implemented automation; two out of them are using open source integrated library automation software (Koha), one library uses in-house built integrated library system (ILS), while the remaining three use different proprietary software for their automation projects; and all the ILSs being used for automation projects are interoperable. The conclusion from the study is that the effective performance of libraries lies in the ability to access research materials and other relevant information contents with remarkable ease. This becomes achievable when libraries adopt and implement automation in their respective domains.  相似文献   
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