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1.
R. Chawla Navendu Goyal Rajneesh Calton Shweta Goyal 《Indian journal of clinical biochemistry : IJCB》2006,21(1):77-82
Early identification of patients with acute myocardial infarction is of prime importance due to the associated very high mortality.
Only 22% of the patients presenting at emergency cardiology care with chest pain have coronary disease. A number of biochemical
tests like CKMB and Troponin-T/I have been introduced for early detection of the coronary syndrome (ACS). Ischemia modified
albumin (IMA) has been recently introduced as a marker of myocardial ischemia. We estimated serum IMA in four sequential samples
from 25 patients admitted to ICCU. Twenty five healthy volunteers formed the control group from which the normal range was
derived. IMA was significantly raised in ischemia patients than in controls as well as compared to the patients who did not
have cardiac ischemia. IMA demonstrated good discrimination between the ischemic and the non-ischemic patients with an Odds
Ratio of 16.9 (6.29–46.87) than CKMB which showed an Odds Ratio of 2.07 (1.18–6.08). Sensitivity and specificity of IMA for
the detection of ACS was 78.0% and 82.7% compared to 58.0% and 60.0%, respectively for the CK-MB assay. The area under the
ROC curve of IMA for ischemic v/s non-ischemic patients was 0.834. IMA appears to be developing into a new and very potent
marker, of cardiac ischemia. 相似文献
2.
The increase in smartphone adoption has been no less than astounding. Unfortunately, the explosive growth has been accompanied by a rash of security problems. A contributing factor to the growing security problem is a lack of education, training, and awareness. In addition, “bring your own device” (BYOD) policies often leave security responsibilities to the competencies of device owners, which compromises security. Today’s students are tomorrow’s employees with responsibilities for protecting their work environment. They need to understand and practice a full-range of mobile security practices so that they can safely access the information assets of their organizations. If students are not engaging in such practices, educational institutions have a responsibility to ensure that students understand how to keep information assets secure. This paper investigates the smartphone security practices of undergraduate college students. Five hundred students in business classes at a regional public university were surveyed to determine their use of recommended smartphone security practices. The study found that many smartphone users did employ some security measures, but a high percentage of them were ignoring potential risks. This suggests a need for increased education, training, and awareness. 相似文献
3.
An analysis of 31,369 bibliographic titles was carried out to obtain statistics on frequently occurring character groups to increase the effective character set with the aim of estimating possible compression factors for text. It was found that a common set could be used to obtain compression ranging between 30 and 53% over a wide variety of original text. 相似文献
4.
Thirty patients with thalassemia major receiving repeated blood transfusion were studied to see their serum parathyroid hormone
(PTH) and calcium status. Serum PTH, serum and 24 h urinary calcium, and serum alkaline phosphatase, phosphorus, and albumin-corrected
calcium levels were determined. Half of these patients, in addition to transfusion, were also supplemented with vitamin D
(60,000 IU for 10d) and calcium (1500 mg/day for 3 months). Serum PTH, and serum and 24 h urinary calcium concentrations of
the patients receiving transfusions were found to be significantly reduced while their serum alkaline phosphatase, phosphorus,
and albumin-corrected calcium levels were not significantly altered when compared to the respective mean values for the control
group. Vitamin D and calcium supplementation significantly increased their serum PTH and calcium levels. Supplementations
also increased urinary excretion of calcium. The results thus suggest that patients with thalassemia have hypoparathyroidism
and reduced serum calcium concentrations that in turn were improved with vitamin D and calcium supplementation. 相似文献
5.
In this paper, a novel neighborhood based document smoothing model for information retrieval has been proposed. Lexical association between terms is used to provide a context sensitive indexing weight to the document terms, i.e. the term weights are redistributed based on the lexical association with the context words. A generalized retrieval framework has been presented and it has been shown that the vector space model (VSM), divergence from randomness (DFR), Okapi Best Matching 25 (BM25) and the language model (LM) based retrieval frameworks are special cases of this generalized framework. Being proposed in the generalized retrieval framework, the neighborhood based document smoothing model is applicable to all the indexing models that use the term-document frequency scheme. The proposed smoothing model is as efficient as the baseline retrieval frameworks at runtime. Experiments over the TREC datasets show that the neighborhood based document smoothing model consistently improves the retrieval performance of VSM, DFR, BM25 and LM and the improvements are statistically significant. 相似文献
6.
Measurement of plasma hemoglobin is useful in variety of clinical conditions. In the present study we have developed a kinetic
method to estimate plasma haemoglobin by using o-tolidine. This method is sensitive, rapid, economical, simple and less influenced
by interfering substances. It measures plasma haemoglobin in the range of 6 to 400 mg/L (normal range < 50 mg/L) in less than
two minutes and can be easily automated. 相似文献
7.
Bineeta Kashyap Nisha Goyal N. P. Singh Iqbal R. Kaur 《Indian journal of clinical biochemistry : IJCB》2018,33(3):334-340
Pleural tuberculosis accounts for nearly 20% of Extra pulmonary tuberculosis. Adenosine deaminase, commonly used biomarker for the diagnosis, is non specific and there is paucity of literature on its correlation with conventional or newer methods for the diagnosis of extra pulmonary forms of TB. The aim of the study was to assess diagnostic potential of T cell function markers [interferon (IFN-γ), interleukin (IL-2) and IFN-γ/IL-2 ratio]; macrophage activation marker [neopterin]; and oxidative stress markers [protein carbonyl and malondialdehyde (MDA)] in pleural tuberculosis. 26 pleural TB cases diagnosed on the basis of suggestive chest X-ray and raised serum ADA levels and healthy controls were included in the study. Pleural fluid specimens were subjected to Zeihl Neelsen staining and culture on Lowenstein Jensen medium. Serum IFN-γ, IL-2, neopterin and protein carbonyl levels detection were done by ELISA and MDA levels were determined by measuring the thiobarbituric acid reactive substances. Median serum levels of IFN-γ, IL-2, IFN-γ/IL-2 ratio, neopterin, protein carbonyl and MDA were significantly different between cases and controls. Levels of all biomarkers except IL-2 were significantly higher in cases with contact history. Mean levels of ADA and ESR were 46.27 U/L and 46.62 mm/hr in PTB cases. AUC for IFN-γ, IL-2, IFN-γ/IL-2 ratio, neopterin, protein carbonyl and MDA were significantly discriminative for cases and controls. IFN-γ/IL-2 ratio was best discriminatory biomarker with highest area under ROC curve. Though no correlation was seen between ADA and any of the six biomarkers, ESR levels correlated significantly with all biomarkers except IL-2 by spearman’s correlation coefficient. Though all the circulating biomarkers under study provide useful supportive evidence for the diagnosis of PTB, further studies involving diverse control groups particularly non-PTB effusion are needed to validate these results. 相似文献
8.
P. Goyal 《Information processing & management》1983,19(2):83-85
This paper presents an entropy based technique for the abbreviation of text strings for use as a control code. Tests were performed using titles from machine readable bibliographic files. Greater than 94% of the titles have been found to generate a unique seven character code. 相似文献
9.
Study on Relation of Metabolic Syndrome with Menopause 总被引：1，自引：0，他引：1
Sapna Goyal Mriganka Baruah Runi Devi Kalpana Jain 《Indian journal of clinical biochemistry : IJCB》2013,28(1):55-60
This study is carried out to determine the prevalence of metabolic syndrome (MS) in 148 women between 36 to 65 years using the International Diabetes Federation criteria in the North-Eastern part of India. The prevalence of MS and all its individual components were found to be significantly higher among postmenopausal as compared to premenopausal and perimenopausal women. Various components of MS except waist circumference shows a significant increase and homeostasis model assessment index for insulin resistance also showed significant differences between the three groups. All the MS diagnostic markers (except serum high density lipoprotein) showed a strong positive correlation with MS score among the groups. Further MS score correlated with indicators of insulin resistance evaluated. This study concluded that MS is highly prevalent among North-East Indian postmenopausal women seeking primary health care and its determinant factors related to age and sedentary habits. Thus recognizing and treating MS early with proper intervention can minimize complication. 相似文献
10.
Bineeta Kashyap Nisha Goyal G. K. Das N. P Singh I. R. Kaur 《Indian journal of clinical biochemistry : IJCB》2018,33(4):483-486
TB as the cause of uveitis varies from 0.5 to 10.5%; low sensitivity of confirmatory laboratory investigations and inconsistency of diagnostic criteria leads to paucity of data. Diagnosis requires a high level of suspicion and is often presumptive based on indirect evidences. Interferon gamma, Interleukin-2 and Neopterin are key biomarkers in immuno-regulation of Mycobacterium tuberculosis infection. The relative shift from Interleukin-2 towards Interferon gamma (Interferon gamma/Interleukin-2) is more discriminatory for active tuberculosis. Protein carbonyl and Malondialdehyde, as oxidative stress markers, characterize active tuberculosis. A case of disseminated TB presenting with acute uveitis had a recurrent tubercular lymphadenitis after completing category I treatment under revised national tuberculosis control programme. The present study evaluates the potential utility of above mentioned biomarkers to predict atypical presentation in difficult cases of tuberculosis. Though tuberculous uveitis is amenable to treatment in early course of disease, the delay in diagnosis can have serious consequences for the patient. 相似文献