Age related changes in lipid peroxidation and antioxidants in elderly people     

Akila V. Prashant  H. Harishchandra  Vivian D'souza  Benedicta D'souza 《Indian journal of clinical biochemistry : IJCB》2007,22(1):131-134

Advanced age is associated with an accumulation of free radical damage, which leads to physiological and clinical modifications. Age related changes resulting from free radical reactions include increasing levels of lipid peroxides, alterations in enzyme activities and greater osmotic fragility. The present study was conducted to estimate the level of lipid peroxidation product-Malondialdehyde and antioxidants Catalase and Glutathione in elderly people. An increase in lipid peroxidation and decrease in antioxidants was observed in normal elderly people. Highly significant increase in MDA and decrease in antioxidants was observed in elderly people when complicated with diabetes and hypertension. Supplementation of antioxidants may prevent further oxidative injury in elderly people.  相似文献   

Comparative Study of Serum Amylase and Lipase in Acute Pancreatitis Patients     

HS Batra  Ashwini Kumar  TK Saha  Pratibha Misra  Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2015,30(2):230-233

To establish utility of single enzymatic marker for the diagnosis of acute pancreatitis. This is a cohort study. Tertiary care centre proven cases of acute pancreatitis (n = 50) admitted in surgery ward between December 2011 and May 2013 were included in the study. Serum amylase and lipase were performed along with many analytes. All relevant data including serum lab values and imaging were collected. All 50 patients included in the study had raised serum lipase, 42 patients had both amylase and lipase raised, 8 patients had amylase normal but lipase raised. In smaller hospitals where limited lab and radiological facilities are available, estimation of serum lipase will be a better choice over serum amylase in diagnosis of acute pancreatitis.  相似文献   

An interdisciplinary and application-oriented approach to teach microfluidics     

M. Mehdi Salek  Vicente Fernandez  Glen D'souza  Josep Puigmartí-Luis  Roman Stocker  Eleonora Secchi 《Biomicrofluidics》2021,15(1)

Microfluidics is a relatively novel interdisciplinary research area with broad applications in chemistry, physics, material science, and biology. Despite the rapid growth of the field, students'' exposure to microfluidic technologies is still limited and often insufficient to appreciate the advantages over other commonly used technologies. To this end, we designed a five-day course, “Microfluidics for microbial ecology,” in which students with very different backgrounds learn the basics of microfluidic technologies and sample a range of applications in microbial ecology. The course was created for Master and Ph.D. students interested in applying microfluidics to their research and, therefore, followed an application-oriented approach. The presentation of critical aspects of fluid flow phenomena at the microscale and an outline of the advantages and constraints of the technology provide students with the background to design and perform microfluidics-based experiments. In order to improve the effectiveness of learning in a class with diverse interests and backgrounds, two active learning exercises were implemented. The first comprised the design of an individualized microfluidics experiment in parallel with the lectures: students were guided to apply each module to their personalized application and discuss it in groups. The second was a group experimental activity, in which students jointly set up, performed, analyzed, and presented a microfluidics-based experiment. Given the multidisciplinary teaching context, the course was able to foster common conceptual ground and promote discussion among students. This application-oriented approach built upon experimental activities and in-class discussion is well suited to promote learning in a technology-related subject such as microfluidics.  相似文献   

Philosophy,philosophy of education,and the education of teachers     

Mario O. D'souza 《Interchange》1992,23(3):255-264

The role of philosophy of education has become seriously blurred with constant cries for practical and immediate answers. The nature of the discipline is such that when practical solutions are demanded of it, it loses its vitality. Philosophy is an intellectual and contemplative exercise; it is a true activity of leisure, one which needs to be enjoyed for its own sake. This intellectual and contemplative activity is of service to the practical concerns of education because choice, action, and judgment — the concerns of the practical realm —depend upon intellectual knowledge. Philosophy of education is, therefore, an essential discipline in the education of the student-teacher.  相似文献