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Gholamhossein Mehralian Hamid Reza Rasekh Peyman Akhavan Ali Rajabzadeh Ghatari 《International Journal of Information Management》2013
During the last decade, intellectual capital (IC) and intangible assets have been widely considered as critical tool to deliver successful business in an intensive-knowledge environment. Accordingly, the main goal of this paper is therefore to develop and prioritize the most important indicators of intellectual capital in knowledge-based industries. Based on an extensive literature review, a valid and reliable questionnaire was designed. In order to data gathering, it was sent out to participants from both academic and university who qualified well in pharmaceutical practice. In order to exact prioritization of indicators, fuzzy TOPSIS technique as a MADM model was used. The fuzzy TOPSIS results revealed participants remark high concerns especially about knowledge and skills of managers and employees regarding to human capital, high concerns particularly about positive climate, ratio of investment in R&D and numbers of R&D projects according to structural capital, while considering the relational capital, more attention was paid to customers and strategic cooperation such as alliances and licensing. 相似文献
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Abdolmotalleb Rezaei Ali Asadi Ahmad Rezvanfar Hajar Hassanshahi 《International Information and Library Review》2009,41(3):163-172
Information system success has been widely discussed in the past two decades. As systems and technologies are being improved and developed, discussions on their effectiveness and evaluation on their success have been continuously debated by researchers, scholars and practitioners throughout the years. Besides the major concern of IS effectiveness, factors influencing IS effectiveness are also important. One of these factors is the organizational factor. Using perceptual measures, this study aims to investigate the influence of organizational factors on MIS success. Survey questionnaires were gathered from 132 Extension Managers from Iran's Agricultural Extension Providers. Seven items were identified to influence MIS success. They are IS department structure, top management support, management style, managerial IT knowledge, goal alignment, resources allocation and IS infrastructure. The study also identified five MIS success dimensions; systems quality, information quality, perceived Ease of use, organizational impact and individual impact. The study found that the MIS success variables are significantly and highly correlated. The study also found all the organizational factors are significantly correlated to the five IS success factors investigated; the system quality, information quality, perceived ease of use, organizational impact and individual impact. Multiple regression analyses also found goal alignment as the highest predictor of IS success, followed by IS department structure, IS infrastructure and management style. 相似文献
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Seyed Ebrahim Alavi Maedeh Koohi Moftakhari Esfahani Soheil Ghassemi Azim Akbarzadeh Gholamhossein Hassanshahi 《Indian journal of clinical biochemistry : IJCB》2014,29(1):84-88
Breast cancer is one of the most frequent cancer types within women population. Hydroxyurea (HU) is a chemotherapy compound for treatment of patients with cancer diagnosis, including breast cancer associated with several adverse effects. In this study, we applied nanotechnology to decreased drug side effects along with improvement of therapeutic index. Liposomation is widely used in modern pharmacological developments in order to enhance the effects of the drugs. To achieve this, in this study a mixture of phosphatidylcholine and cholesterol was made up and HU was added to the resultant mixture, was then pegylated using Polyethylene Glycol 2000 to increase resistance, applicability and solubility. The mean diameters of nanoliposomal and pegylated nanoliposomal HU were measured by Zeta sizer device and obtained about 402.5 and 338.2 nm. The efficiency of non-pegylated and pegylated liposomal HU was 70.8 and 64.2, respectively. Releasing HU in both formulations was estimated about 25.8 and 21.7 %. Also, this study investigated the cytotoxicity effect of nanoliposomal and pegylated nanoliposomal HU using MTT assay. Results of this investigation showed that the cytotoxic properties of pegylated HU was 3.6 % more than those non-pegylated form, while was 38.93 % more than ordinary from of HU. This study showed that the stability, releasing pattern and cytotoxicity of the pegylated nanoliposomal HU is better than that of nanoliposomal HU. 相似文献
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