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Fadhaa A. Ghafil Bassim I. Mohammad Hussain S. Al-Janabi Najah R. Hadi Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81
Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses. 相似文献
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Zhouchao Wei Amin Yousefpour Hadi Jahanshahi Uǧur Erkin Kocamaz Irene Moroz 《Journal of The Franklin Institute》2021,358(1):814-833
Having found hidden hyperchaos in a 5D self-exciting homopolar disc dynamo, we study the existence of a Hopf bifurcation, which leads to unstable limit cycles bifurcating from a stable equilibrium. Hidden chaos with only stable equilibria can be observed from the Hopf bifurcation: a typical way to enable hidden attractors to be located. We then provide a new fuzzy controller, and a fast fuzzy disturbance observer, based on terminal sliding mode control for synchronization of the hyperchaotic system. Fuzzy inference is considered to weaken the chattering phenomena. Using Lyapunov stability theory, the stability of the closed-loop system is proved. Finally, simulations of synchronization are illustrated to show the efficient performance of the designed control method via external disturbances and dynamic uncertainties. 相似文献
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Demand for and productivity analysis of Turkish public theater 总被引：1，自引：0，他引：1
We estimate a demand function for live theater provided by the General Directorate of State Theaters in Turkey. We show that demand is more elastic in less developed cities, that attendance is not significantly affected by various qualitative variables, and that the government's practice of offering free passes to government officials is an ineffective way of increasing paid attendance. Comedies and musicals both show significantly higher attendance. Having a Turkish author does not significantly affect attendance. Having a known author significantly increases attendance for more developed cities but not for less developed cities. Being the opening season significantly reduces attendance in less developed cities but has no effect in more developed cities. We also present evidence of inefficiency in state theaters in Turkey through a performance of plays equation in which we evaluate the determinants of the number of performances per play. 相似文献
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Hadi Yaghoubinejad Nourollah Zarrinabadi Dariush Nejadansari 《Teachers and Teaching》2017,23(2):127-140
Research has shown that lack of motivation on either students or teachers’ part negatively influences language learning. The latter case is a serious problem in this regard, since an unmotivated teacher will extinguish his learners’ enthusiasm and energy for learning. This study employed a mixed-method approach to investigate the demotivating factors for Iranian junior high school teachers. For the quantitative stage of the study, a questionnaire on demotivation was distributed among 105 participant teachers to find out the dominant demotivating factors. In the qualitative stage, and in order to gain a better picture of the salient demotivating factors and the reasons behind them, a set of semi-structured interviews with 10 volunteer teachers were conducted. The results indicated that lack of social recognition and respect, few adequate rewards, lack of supports or understanding regarding English education, and a large number of students in a single English class were the major demotivating factors for Iranian teachers. In the interviews, it was found that the participants perceived the first two items as specific to Iranian educational context. Finally, the implications for policy-makers and material developers and suggestions for future researchers are discussed. 相似文献
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Dehghani MH Mahvi AH Jahed GR Sheikhi R 《Journal of Zhejiang University. Science. B》2007,8(7):493-497
The objective of the investigation was to study the application of ultrasound reactor technology （USRT） as a disinfectant for reduction of fungi from sewage effluent. Fungi are carbon heterotrophs that require preformed organic compounds as carbon sources. USRT is an attractive means to improve water quality because of the system simplicity and no production of toxic by-products. An ultrasound reactor produces strong cavitation in aqueous solution causing shock waves and reactive free radicals by the violent collapse of the cavitation bubble. These effects should contribute to the physical disruption of microbial structures and inactivation of organisms. There was significant reduction in fungal growth, with decreased fungal growth with increasing USRT. In this study, ultrasound irradiation at a frequency of 42 kHz was used to expose suspensions of fungi to evaluate the disinfection efficacy of the ultrasound reactor. Also, this study showed that in this system more than 99% reduction of sewage fungi was achieved after 60 min. 相似文献
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ALSHOAIBI Abdulnaser M HADI M.S.A ARIFFIN A.K. 《浙江大学学报(A卷英文版)》2007,8(2):228-236
INTRODUCTION The finite element method (FEM) has proved to be very well suited for the study of fracture mechanics. Nevertheless, modelling the propagation of a crack through a finite element mesh turns out to be difficult because of the modification of the mesh topology. Use of crack propagation laws based on stress inten-sity factor range is the most successful engineering application of fracture mechanics. The stress intensity factors are a very important parameter in fracture analys… 相似文献
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Murooj L. Majeed Fadhaa A. Ghafil Ghizal Fatima Najah R. Hadi Hind F. Mahdi 《Indian journal of clinical biochemistry : IJCB》2021,36(1):74
Curcumin has a potent antioxidant and anti-inflammatory properties that may suppress inflammatory component of atherosclerosis. It has been demonstrated that curcumin derivatives can reduce the formation of arterial fatty streaks in cholesterol-fed rabbits. Therefore in this study we evaluated the protective effects of Curcumin on the progression of atherosclerosis. 20 mature rabbits were included for this study; they were randomly divided into four groups each of 5. Group 1: (normal control) were fed corn pellets diet and tab water, group 2: (high cholesterol diet control) were kept on cholesterol rich diet (2% cholesterol) and tab water. Group 3: (cholesterol and rosuvastatin treated group) were kept on cholesterol rich diet (2% cholesterol) and 2.5 mg/kg/day Rosuvastatin dispersed in DW and given orally, group 4: (cholesterol and curcumin treated group) were kept on cholesterol rich diet (2% cholesterol) and 0.2% curcumin added with corn pellets. The study continued for 12 weeks then assessment of serum level of high sensitive C-reactive protein, ICAM1, VCAM1 and PCSK9 was carried out at the end of the study. Total antioxidant activity of curcumin was also determined. Histopathological examination of aortic tissues for atherosclerotic changes was also carried out. Atherogenic (cholesterol rich diet) induced an increment in serum level of TC, LDL, VLDL and TG with concomitant decrement in serum level of HDL and increased atherogenic index. Treatment with curcumin produced substantial reduction in serum TC, LDL, TG with no effect on HDL level thus decreased atherogenic index. Rabbits treated with curcumin showed a significant reduction in the serum level of high sensitive C-reactive protein, ICAM1, VCAM, PCSK9 serum expression and aortic total antioxidant capacity. Curcumin has a potent anti-inflammatory and anti- oxidant effects against atherosclerosis so exerts a protective role by decreasing lipid oxidation and inflammatory markers. 相似文献
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Yousuf Almurtaji John Everatt Nasser S. Almenaye Ahmad S. Alazemi Dalal Abdul Hadi Alradaan 《Emotional and Behavioural Difficulties》2018,23(2):141-153
Previous studies have found significant differences between the classroom behaviour of boys and girls. Most are within a single broad cultural context and little work has been done within an Arabic/Kuwaiti one. The main aim was to investigate the differences in behaviour between boys and girls in Kuwait primary schools. Data were collected that provided comparisons across questionnaires between parent and teacher returns for over 430 students. Separate teacher observations of students (n = 671) and classroom researcher observations were also obtained. Significant differences were found across the scales, indicating higher levels of externalising misbehaviour among boys than girls. A comparison with three studies conducted in other cultural contexts using the same strengths and difficulties instrument as used in this study found similarities and differences in results between the behaviour of boys and girls. 相似文献
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Cultural Studies of Science Education - In this forum, I explore how science teaching and learning as a moral act needs to be based in the context of a local community. I agree with Alaina... 相似文献