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Arun Kumar B. S. Dhillon D. N. Rao Geetha Menon Hari Shankar L. K. Dhaliwal Maiti Leema Nomita Chandhiok Neeta Kumar Rohini Sehgal Suneeta Mittal Sumitu Sahdev Kandpal Shobha V. L. Jindal 《Indian journal of clinical biochemistry : IJCB》2012,27(4):405-409
Malondialdehyde (MDA) is widely used as oxidative stress biomarker in biomedical research. Plasma is stored in deep freezers generally till analysis. Effect of such storage on MDA values, which may be variable and prolong, was incidentally observed in the ongoing study which is to estimate oxidative stress with oral iron. Plasma from blood samples of pregnant women (20–30 years age) in third trimester of singleton pregnancy (n = 139), consuming oral iron tablets was stored at −20 °C with intention of MDA estimation, as soon as possible. However logistic problems led this storage for prolonged and variable period (1–708 days). When values of MDA estimated using “Ohkawa” 79 method and readings were plotted against time to check the temporal effect, it showed a hyperbolic curve. Standard deviation (SD) was lowest when samples were tested within 3 weeks time. The samples analyzed within 3 weeks had mean ± SD value of 31.59 ± 26.11 μmol/L, while 123.7 ± 93.97 and 366.5 ± 189.8 μmol/L for samples stored for 1–3 and 4 months to 1 year respectively. Mean ± SD were 539.9 ± 196.8 in the samples store for more than a year. Rate of change in values was also lowest (0.0433 μmol/L/day) in the samples tested within first 3 weeks, which rose to 1.2 μmol/L/day during 3 month’s storage. This rate peaked at storage of 120 days (1.87 μmol/L/day) and fell to 0.502 μmol/L/day in the second year of storage. It is concluded that at −20 °C, only 3 weeks of storage time should be considered valid for fairly acceptable stability in MDA values. 相似文献
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A. S. Sane Shobha A. Chokshi D. P. Barad V. C. Shah V. Mathur S. C. Kukreti 《Indian journal of clinical biochemistry : IJCB》1989,4(1):26-30
To test the concept of intense psychogenic stress manifesting as organic lesion, effect of pre-operative stress on serum lipid peroxide levels in 30 otherwise healthy patients to undergo major abdominal elective surgery has been studied and compared with healthy controls. Significant elevations in serum lipid peroxide levels both on hospitalization and at pre-operative stage were noticed in comparison with healthy controls. However, serum lipid peroxide levels at pre-operative stage did not show significant fluctuations in comparison with those at the time of admission, suggestive of no probable further increment in autoxidation of unsaturated fatty acids of membrane lipids and proper handling by scavenging enzyme system. 相似文献
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In this paper, the principles of Doppler processing to detect and track human movers in indoor environments are presented. The topics discussed include the micro-Doppler characteristics of humans, the azimuth, elevation and range tracking of humans using Doppler, spatial and frequency diversity, the effect of walls, and the characteristics of dynamic clutters from non-humans. The studies are supported by simulation and measurement results. 相似文献
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Shobha Madan 《Resonance》2014,19(4):323-337
George Pólya (1887–1985) was a brilliant Hungarian mathematician; and many of you may have come across his famous (bestseller) book How to Solve it. Elsewhere in this issue you will find a more complete biography of Pólya. Here we will talk about some of his work in complex analysis. Among Pólya’s contemporaries were mathematicians like Leopold (Lipót) Fejér, his thesis advisor, Adolf Hurwitz (1859–1919), G H Hardy (1877–1947), Gábor Szegö (1895–1985). 相似文献
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Associations between Parental Psychological and Behavioral Control and Youth Internalized and Externalized Behaviors 总被引：9，自引：0，他引：9
In this study, psychological control of children was conceptually and empirically distinguished from behavioral control. Further, it was demonstrated as hypothesized that psychological control was more predictive of adolescent internalized problems, and that behavioral control was more predictive of externalized problems. Subjects were 473 fifth-, eighth-, and tenth-grade males and females from a Southern suburb. Control was measured by the Child Report of Parent Behavior Inventory and the Colorado Self-Report of Family Functioning Inventory. Problem behaviors were measured with the Child Behavior Checklist. First- and second-order factor analyses discriminated psychological and behavioral control, and structural equation analyses demonstrated the differential prediction of internalized and externalized problems. These last analyses were conducted using youth-reported data and validated using a subsample of 227 mother-youth pairs. 相似文献
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Maternal and fetal indicators of oxidative stress during intrauterine growth retardation (IUGR) 总被引：1，自引：0，他引：1
Ullas Kamath Guruprasad Rao Shobha U Kamath Lavanya Rai 《Indian journal of clinical biochemistry : IJCB》2006,21(1):111-115
The present study demonstrates the possibility of increased lipid peroxidation and protein oxidation in both maternal and
fetal erythrocytes as markers of oxygen radical activity during intrauterine growth retardation. The erythrocyte MDA levels
were significantly elevated in mothers of IUGR babies when compared to controls (p<0.01). The endogenous protein damage due
to oxidative stress was significantly higher in IUGR mothers when compared to controls (p<0.05). Similarly the proteolytic
activity in erythrocyte lysates against oxidatively damaged hemoglobin was significantly increased in mothers of IUGR babies
compared to controls (p<0.001).
In fetuses born with IUGR, both lipid peroxidation and proteolytic activity were significantly increased when compared to
normal newborns (p<0.01).
The result of this study indicates that oxidative stress was induced both in IUGR babies and their mothers which is manifested
as increased lipid peroxidation and protein oxidant damage. 相似文献
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