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Yoshihiro Okamoto Tomoyo Mita Testuri Kodama Yoshimitsu Gotoh Naoya Fujita Takashi Fukui Toshiyuki Masuzawa 《Indian journal of clinical biochemistry : IJCB》2015,30(3):351-356
We measured serum soluble vascular endothelial growth factor receptor 1 (sVEGFR1) and receptor 2 (sVEGFR2) levels in healthy Japanese individuals in order to establish a reference value using a specific ELISA. Significant differences were observed in serum sVEGFR1 and sVEGFR2 levels between children and adults. To demonstrate the usefulness of the reference value for children, we measured serum sVEGFR1 and sVEGFR2 levels in children with diarrhea positive (D+) hemolytic uremic syndrome (HUS) as a preliminary study. Serum sVEGFR2 levels in children with HUS were markedly higher than those in healthy children from the onset of D + HUS. The reference value for healthy children in the present study will allow normal and pathological conditions to be discriminated from each other in future study 相似文献
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Keitaro Kubo Daisuke Miyazaki Shigeharu Tanaka Shozo Shimoju Naoya Tsunoda 《Journal of sports sciences》2015,33(7):665-669
The purpose of this study was to investigate the relationship between Achilles tendon properties and foot strike patterns in long-distance runners. Forty-one highly trained male long-distance runners participated in this study. Elongation of the Achilles tendon and aponeurosis of the medial gastrocnemius muscle were measured using ultrasonography, while the participants performed ramp isometric plantar flexion up to the voluntary maximum. The relationship between the estimated muscle force and tendon elongation during the ascending phase was fit to a linear regression, the slope of which was defined as stiffness. In addition, the cross-sectional area of the Achilles tendon was measured using ultrasonography. Foot strike patterns (forefoot, midfoot and rearfoot) during running were determined at submaximal velocity (18 km · h?1) on a treadmill. The number of each foot strike runner was 12 for the forefoot (29.3%), 12 for the midfoot (29.3%) and 17 for the rearfoot (41.5%). No significant differences were observed in the variables measured for the Achilles tendon among the three groups. These results suggested that the foot strike pattern during running did not affect the morphological or mechanical properties of the Achilles tendon in long-distance runners. 相似文献
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Andreas Karatsolis Suguru Ishizaki Marsha Lovett Stacie Rohrbach Mollie Kaufer 《Technical Communication Quarterly》2016,25(4):244-259
This article presents an experimental pedagogical framework for providing technical professionals with practice on writing skills focusing on the development of their metacognitive rhetorical awareness. The article outlines the theoretical foundation that led to the development of the framework, followed by a report of a pilot study involving information technology professionals in a global setting using an online learning environment that was designed based on the framework. 相似文献
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Naoya Todo 《Structural equation modeling》2016,23(5):695-712
In longitudinal design, investigating interindividual differences of intraindividual changes enables researchers to better understand the potential variety of development and growth. Although latent growth curve mixture models have been widely used, unstructured finite mixture models (uFMMs) are also useful as a preliminary tool and are expected to be more robust in identifying classes under the influence of possible model misspecifications, which are very common in actual practice. In this study, large-scale simulations were performed in which various normal uFMMs and nonnormal uFMMs were fit to evaluate their utility and the performance of each model selection procedure for estimating the number of classes in longitudinal designs. Results show that normal uFMMs assuming invariance of variance–covariance structures among classes perform better on average. Among model selection procedures, the Calinski–Harabasz statistic, which has a nonparametric nature, performed better on average than information criteria, including the Bayesian information criterion. 相似文献
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Masayuki Konishi Masaki Takahashi Naoya Endo Shigeharu Numao Shun Takagi Masashi Miyashita 《Journal of sports sciences》2013,31(3):248-255
Abstract The aim of this study was to investigate the effects of sleep deprivation on autonomic and endocrine functions during the day and on exercise tolerance in the evening. Ten healthy young males completed two, 2-day control and sleep deprivation trials. For the control trial, participants were allowed normal sleep from 23:00 to 07:00 h. For the sleep deprivation trial, participants did not sleep for 34 h. Autonomic activity was measured from 19:00 h on day 1 to 16:00 h on day 2 by frequency-domain measures of heart rate variability. Endocrine function was examined by measuring adrenocorticotropic hormone and cortisol from venous blood samples collected on day 2 at 09:00, 13:00, and 17:00 h and immediately after an exercise tolerance testing. Autonomic regulation, particularly parasympathetic regulation estimated from the high-frequency component of heart rate variability analysis, was significantly higher in the sleep deprivation trial than in the control trial in the morning and afternoon of day 2. Plasma adrenocorticotropic hormone concentrations were significantly higher at 09:00 and 13:00 h of day 2 under sleep deprivation. Heart rate during exercise was significantly lower following sleep deprivation. Therefore, the effects of sleep deprivation on autonomic regulation depend on the time of the day. 相似文献
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In the application of 2-D adaptive filters, a large amount of data must be processed and real-time processing is often required. In this paper, a new parallel-form realization of 2-D adaptive separable-denominator state-space filters suitable for high-speed processing is proposed. First, the 2-D local state-space model suitable for parallel processing is introduced. Next, the adaptive algorithm for this model is developed. This algorithm is based on the delayed least mean square (DLMS) method. In addition, the computation time required for the update of the coefficients is investigated. Finally, the proposed technique is applied to the design of 2-D digital filters in the spatial domain. 相似文献
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Kubo K Ohgo K Takeishi R Yoshinaga K Tsunoda N Kanehisa H Fukunaga T 《Research quarterly for exercise and sport》2006,77(4):408-416
The purpose of this study was to investigate the effects of series elasticity on the torque-angle relationship of the knee extensors in vivo. Forty-two men volunteered to take part in the present study. The participants performed maximal voluntary isometric contractions at eight knee-joint angles (40, 50, 60, 70, 80, 90, 100, 110 degrees). The elongation of the tendon and aponeurosis of the vastus lateralis muscle was directly measured by ultrasonography, while the participants performed ramp isometric knee extensions to the voluntary maximum at 800 of knee angle. There was no significant difference in the torque value between 50 degrees and 100 degrees, although there was variation in the shape of the "torque-angle" relationship. The variability in the torque-angle curve was not affected by the activation level of agonist and antagonist muscles and the moment arm length. The ratio of torque at 1000 compared to that at 50 degrees was significantly (r(2) = 18-23 %) correlated to the maximal elongation and strain (to initial length) of the tendon structures. These results suggest that increased compliance of tendon structures of the knee extensors may contribute to variations in the torque-angle curves of the knee extensors. 相似文献
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Yoshihiro Okamoto Mayuri Tanaka Asami Kasahara Takazumi Hara Yoshimitsu Gotoh Naoya Fujita Takashi Fukui Toshiyuki Masuzawa 《Indian journal of clinical biochemistry : IJCB》2012,27(4):400-404
Most cytokine receptors including interleukin (IL)-9 have soluble counterparts in body fluids. We planned to investigate the pathophysiological significance of the serum soluble IL-9 receptor (sIL-9R) level. We determined the serum sIL-9Rα chain (sIL-9Rα) levels in 96 healthy Japanese individuals to establish a control value by means of specific human sIL-9Rα ELISA, followed by a preliminary application in a patient with diarrhea positive hemolytic uremic syndrome. Age was negatively correlated with the sIL-9Rα level (Spearman r = −0.241, n = 96, p = 0.0180). The serum sIL-9Rα level showed a progressive decline to the normal adult level by the age of 30. The serum sIL-9Rα level of the patient with HUS was markedly higher than those of the age-matched control from the onset of the disease. Because of the remarkable age-dependent variability of sIL-9Rα in healthy subjects, disease-related changes, as well as therapy-dependent alterations, should be considered with caution. Thus, it is recommended that when the serum sIL-9Rα levels of patients are evaluated, the values should be compared with those of age-matched controls. The established control value will be used to discriminate between normal and the pathological conditions in our future studies. 相似文献
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Keitaro Kubo Daisuke Miyazaki Toshihiro Ikebukuro Hideaki Yata Masaji Okada Naoya Tsunoda 《Journal of sports sciences》2017,35(8):742-748
The aim of the present study was to investigate and compare muscle and tendon stiffness under active conditions in sprinters and untrained participants. In total, 14 sprinters and 24 untrained men participated in this study. Active muscle stiffness in the medial gastrocnemius muscle was calculated based on changes in estimated muscle force and fascicle length during fast stretching after submaximal isometric contractions. Tendon stiffness was determined during isometric plantar flexion using ultrasonography. No significant differences were observed in active muscle stiffness between sprinters and untrained men at any torque levels. Furthermore, no significant difference was noted in tendon stiffness between the two groups. These results suggest that muscle and tendon mechanical properties in the plantar flexors under active conditions are similar in sprinters and untrained participants. 相似文献
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