排序方式： 共有7条查询结果，搜索用时 62 毫秒
1
1.
Nicolaas J. Moolenijzer 《Quest (Human Kinetics)》2013,65(1):32-43
Many contemporary social commentators claim that we are now living in “New Times.” Other labels used for the same period (by different commentators) are postmodeenity, the information age, late-modernity, high-modernity, the age of uncertainty. In defining these times, it is common to read of the information explosion, the increased pace of material and institutional change, globalization, information technologies, increaed reliance on experts and abstract systems, the end of permanent structures or knowledge or meaning, reflexive modernization, the risk society, and a heightened level of increased anxiety. This paper discusses the evolving relationship between identity, knowledge, change, and uncertainty in the context of new times and explores the issue of the possible consequences of new times for physical education in higher education. 相似文献
2.
3.
4.
Arthur James Swart Nicolaas Luwes Lienie Olwagen Cameron Greyling Carel Korff 《European Journal of Engineering Education》2017,42(6):653-667
Academics must be encouraged to reflect on their teaching, to apply new pedagogies to support student learning and to report on the results of these actions, which really forms part of programmes relating to Scholarship of Teaching and Learning (SoTL). However, there seems to be resistance among some academics to get involved in these programmes due to fear of change or discrimination. The purpose of this article is to highlight the perceptions of four academics from different engineering fields towards such a programme from a University of Technology in South Africa. A qualitative study is employed where a focus group interview was used to gather data which are correlated to the SoTL unicycle detailed in the article. A benefit of joining an SoTL programme includes ‘developing a teaching action plan’ while a key challenge relates to time concerns. An implication may be to stimulate awareness among non-participating academics about what an SoTL programme really engenders. 相似文献
5.
Tijl Vermassen Charles Van Praet Filip Poelaert Nicolaas Lumen Karel Decaestecker Piet Hoebeke Simon Van Belle Sylvie Rottey Joris Delanghe 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(3):439-449
Introduction
Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in asparagine-linked-(N-)-glycosylation were observed between healthy volunteers (HV), patients with benign prostate hyperplasia and prostate cancer patients, a difference could exist in biochemical parameters and urinary N-glycosylation between HV and prostatitis patients. We therefore investigated if prostatic protein glycosylation could improve the diagnosis of prostatitis.Materials and methods
Differences in serum and urine biochemical markers and in total urine N-glycosylation profile of prostatic proteins were determined between HV (N = 66) and prostatitis patients (N = 36). Additionally, diagnostic accuracy of significant biochemical markers and changes in N-glycosylation was assessed.Results
Urinary white blood cell (WBC) count enabled discrimination of HV from prostatitis patients (P < 0.001). Urinary bacteria count allowed for discriminating prostatitis patients from HV (P < 0.001). Total amount of biantennary structures (urinary 2A/MA marker) was significantly lower in prostatitis patients compared to HV (P < 0.001). Combining the urinary 2A/MA marker and urinary WBC count resulted in an AUC of 0.79, 95% confidence interval (CI) = (0.70–0.89) which was significantly better than urinary WBC count (AUC = 0.70, 95% CI = [0.59–0.82], P = 0.042) as isolated test.Conclusions
We have demonstrated the diagnostic value of urinary N-glycosylation profiling, which shows great potential as biomarker for prostatitis. Further research is required to unravel the developmental course of prostatic inflammation.Key words: diagnostic marker, prostatitis, urinary asparagine-linked glycosylation 相似文献6.
Julianne D. van der Berg Paul J. B. Willems Jeroen H. P. M. van der Velde Hans H. C. M. Savelberg Nicolaas C. Schaper Miranda T. Schram 《Journal of sports sciences》2016,34(19):1867-1873
As accelerometers are commonly used for 24-h measurements of daily activity, methods for separating waking from sleeping time are necessary for correct estimations of total daily activity levels accumulated during the waking period. Therefore, an algorithm to determine wake and bed times in 24-h accelerometry data was developed and the agreement of this algorithm with self-report was examined. One hundred seventy-seven participants (aged 40–75 years) of The Maastricht Study who completed a diary and who wore the activPAL3? 24 h/day, on average 6 consecutive days were included. Intraclass correlation coefficient (ICC) was calculated and the Bland–Altman method was used to examine associations between the self-reported and algorithm-calculated waking hours. Mean self-reported waking hours was 15.8 h/day, which was significantly correlated with the algorithm-calculated waking hours (15.8 h/day, ICC = 0.79, P = < 0.001). The Bland–Altman plot indicated good agreement in waking hours as the mean difference was 0.02 h (95% limits of agreement (LoA) = ?1.1 to 1.2 h). The median of the absolute difference was 15.6 min (Q1–Q3 = 7.6–33.2 min), and 71% of absolute differences was less than 30 min. The newly developed automated algorithm to determine wake and bed times was highly associated with self-reported times, and can therefore be used to identify waking time in 24-h accelerometry data in large-scale epidemiological studies. 相似文献
7.
David Turnbull Henry Krips Val Dusek Steve Fuller Alan Sokal Jean Bricmont Alan Frost Alan Chalmers Anna Salleh Alfred I. Tauber Yvonne Luxford Nicolaas Rupke Steven French Peter G. Brown Hugh LaFollette Peter Machamer Nicolas Rasmussen Andy J. Miller Marya Schechtman Ross S. West John Forge David Oldroyd Nancy Demand Darrin W. Belousek Warren Schmaus Sungook Hong Alan Chalmers Rachel A. Ankeny Peter Anstey Jeremy Butterfield Harshi Gunawardena 《Metascience》2000,9(3):347-498
1